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References

Aarons, V. (Ed.) (2016). Third-generation holocaust narratives: Memory in memoir and fiction. Lanham, MD: Lexington Books.Google Scholar

Abrams, M. S. (1999). Intergenerational transmission of trauma: Recent contributions from the literature of family systems approaches to treatment. American Journal of Psychotherapy, 53, 225–231. doi:10.1176/appi.psychotherapy.1999.53.2.225Google Scholar

Alexander, J. C. (2004). Toward a theory of cultural trauma. Cultural Trauma and Collective Identity, 76, 620–639. doi:10.1525/california/9780520235946.003.0001Google Scholar

American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington, DC: Author.Google Scholar

Anway, M. D., Cupp, A. S., Uzumcu, M., & Skinner, M. K. (2005). Epigenetic transgenerational actions of endocrine disruptors and male fertility. Science, 308, 1466–1469. doi:10.1126/science.1108190Google Scholar

Argenti, N., & Schramm, K. (2009). Remembering violence: Anthropological perspectives on intergenerational transmission. New York: Berghahn Books.Google Scholar

Azarian-Ceccato, N. (2010). Reverberations of the Armenian genocide: Narrative's intergenerational transmission and the task of not forgetting. Narrative Inquiry, 20, 106–123. doi:10.1075/ni.20.1.06azaGoogle Scholar

Bader, H. N., Bierer, L. M., Lehrner, A., Makotkine, I., Daskalakis, N. P., & Yehuda, R. (2014). Maternal age at Holocaust exposure and maternal PTSD independently influence urinary cortisol levels in adult offspring. Frontiers in Endocrinology, 5, 1–8. doi:10.3389/fendo.2014.00103Google Scholar

Bale, T. L. (2014). Lifetime stress experience: Transgenerational epigenetics and germ cell programming. Dialogues in Clinical Neuroscience, 16, 297–305.Google Scholar

Barocas, H. A., & Barocas, C. B. (1980). Separation-individuation conflicts in children of Holocaust survivors. Journal of Contemporary Psychotherapy, 11, 6–14. doi:10.1007/BF00946270Google Scholar

Barron, I. G., & Abdallah, G. (2015). Intergenerational trauma in the occupied Palestinian territories: Effect on children and promotion of healing. Journal of Child & Adolescent Trauma, 8, 103–110. doi:10.1007/s40653-015-0046-zGoogle Scholar

Betancourt, T. S., McBain, R. K., Newnham, E. A., & Brennan, R. T. (2015). The intergenerational impact of war: Longitudinal relationships between caregiver and child mental health in postconflict Sierra Leone. Journal of Child Psychology and Psychiatry, 56, 1101–1107. doi:10.1111/jcpp.12389Google Scholar

Bezo, B., & Maggi, S. (2015). Living in “survival mode”: Intergenerational transmission of trauma from the Holodomor genocide of 1932–1933 in Ukraine. Social Science & Medicine, 134, 87–94. doi:10.1016/j.socscimed.2015.04.009Google Scholar

Brach, C., & Fraserirector, I. (2000). Can cultural competency reduce racial and ethnic health disparities? A review and conceptual model. Medical Care Research and Review, 57(Suppl. 2), 181–217. doi:10.1177/1077558700057001S09Google Scholar

Brave Heart, M. Y. H. (1998). The return to the sacred path: Healing the historical trauma and historical unresolved grief response among the Lakota through a psychoeducational group intervention. Smith College Studies in Social Work, 68, 287–305. doi:10.1080/00377319809517532Google Scholar

Breslau, N. (2009). The epidemiology of trauma, PTSD, and other posttrauma disorders. Trauma, Violence & Abuse, 10, 198–210. doi:10.1177/1524838009334448Google Scholar

Bronfenbrenner, U. (1977). Toward an experimental ecology of human development. American Psychologist, 32, 513–531. doi:10.1037/0003-066X.32.7.513Google Scholar

Bronfenbrenner, U. (2009). The ecology of human development: Experiments by nature and design. Cambridge, MA: Harvard University Press.Google Scholar

Calhoun, L. G., & Tedeschi, R. G. (Eds.) (2014). Handbook of posttraumatic growth: Research and practice. New York: Routledge.Google Scholar

Carpenter, T., Grecian, S., & Reynolds, R. (2015). Sex differences in early life programming of the hypothalamic-pituitary-adrenal axis in humans suggest increased vulnerability in females. Psychoneuroendocrinology, 61, 32. doi:10.1016/j.psyneuen.2015.07.476Google Scholar

Chaitin, J., & Steinberg, S. (2008). “You should know better”: Expressions of empathy and disregard among victims of massive social trauma. Journal of Aggression, Maltreatment & Trauma, 17, 197–226. doi:10.1080/10926770802344851Google Scholar

Champagne, D. L., Bagot, R. C., van Hasselt, F., Ramakers, G., Meaney, M. J., De Kloet, E. R., … Krugers, H. (2008). Maternal care and hippocampal plasticity: Evidence for experience-dependent structural plasticity, altered synaptic functioning, and differential responsiveness to glucocorticoids and stress. Journal of Neuroscience, 28, 6037–6045. doi:10.1523/JNEUROSCI.0526-08.2008Google Scholar

Chodoff, P. (1963). Late effects of the concentration camp syndrome. Archives of General Psychiatry, 8, 323–333. doi:10.1001/archpsyc.1963.01720100013002Google Scholar

Chorbov, V. M., Todorov, A. A., Lynskey, M. T., & Cicero, T. J. (2011). Elevated levels of DNA methylation at the OPRM1 promoter in blood and sperm from male opioid addicts. Journal of Opioid Management, 7, 258. doi:10.5055/jom.2011.0067Google Scholar

Chrousos, G. P. (2009). Stress and disorders of the stress system. Nature Reviews Endocrinology, 5, 374–381. doi:10.1038/nrendo.2009.106Google Scholar

Cortessis, V. K., Thomas, D. C., Levine, A. J., Breton, C. V., Mack, T. M., Siegmund, K. D., … Laird, P. W. (2012). Environmental epigenetics: Prospects for studying epigenetic mediation of exposure–response relationships. Human Genetics, 131, 1565–1589. doi:10.1007/s00439-012-1189-8Google Scholar

Danieli, Y. (1985). The treatment and prevention of long-term effects and intergenerational transmission of victimization: A lesson from Holocaust survivors and their children. In Figley, C. R. (Ed.), Trauma and its wake (pp. 295–313). New York: Brunner/Mazel.Google Scholar

Danieli, Y. (Ed.) (1998). International handbook of multigenerational legacies of trauma. New York: Plenun Press.Google Scholar

Daskalakis, N. P., Cohen, H., Cai, G., Buxbaum, J. D., & Yehuda, R. (2014). Expression profiling associates blood and brain glucocorticoid receptor signaling with trauma-related individual differences in both sexes. Proceedings of the National Academy of Sciences, 111, 13529–13534. doi:10.1073/pnas.1401660111Google Scholar

Daskalakis, N. P., Oitzl, M. S., Schächinger, H., Champagne, D. L., & de Kloet, E. R. (2012). Testing the cumulative stress and mismatch hypotheses of psychopathology in a rat model of early-life adversity. Physiology & Behavior, 106, 707–721. doi:10.1016/j.physbeh.2012.01.015Google Scholar

Daxinger, L., & Whitelaw, E. (2012). Understanding transgenerational epigenetic inheritance via the gametes in mammals. Nature Reviews Genetics, 13, 153–164. doi:10.1038/nrg3188Google Scholar

DeGruy, J. (2017). Post traumatic slave syndrome: America's legacy of enduring injury and healing: Milwaukee, WI: Uptone Press.Google Scholar

de Jong, J. (Ed.) (2006). Trauma, war, and violence: Public mental health in socio-cultural context: New York: Kluwer Academic.Google Scholar

De Kloet, C., Vermetten, E., Geuze, E., Kavelaars, A., Heijnen, C., & Westenberg, H. (2006). Assessment of HPA-axis function in posttraumatic stress disorder: Pharmacological and non-pharmacological challenge tests, a review. Journal of Psychiatric Research, 40, 550–567. doi:10.1016/j.jpsychires.2005.08.002Google Scholar

De Kloet, E. R., Joëls, M., & Holsboer, F. (2005). Stress and the brain: From adaptation to disease. Nature Reviews Neuroscience, 6, 463–475. doi:10.1038/nrn1683Google Scholar

Desai, N., Ludgin, J., Sharma, R., Anirudh, R. K., & Agarwal, A. (2017). Female and male gametogenesis. In Falcone, T. & Hurd, W.W. (Eds.), Clinical reproductive medicine and surgery (pp. 43–62). New York: Springer.Google Scholar

de Tubert, R. H. (2006). Social trauma: The pathogenic effects of untoward social conditions. International Forum of Psychoanalysis, 15, 151–156. doi:10.1080/08037060500526037Google Scholar

Dias, B. G., & Ressler, K. J. (2014). Experimental evidence needed to demonstrate inter- and trans-generational effects of ancestral experiences in mammals. Bioessays, 36, 919–923. doi:10.1002/bies.201400105Google Scholar

Dietz, D. M., LaPlant, Q., Watts, E. L., Hodes, G. E., Russo, S. J., Feng, J., … Nestler, E. J. (2011). Paternal transmission of stress-induced pathologies. Biological Psychiatry, 70, 408–414. doi:10.1016/j.biopsych.2011.05.005Google Scholar

Dimsdale, J. E. (1974). The coping behavior of Nazi concentration camp survivors. American Journal of Psychiatry, 131, 792–797. doi:10.1176/ajp.131.7.792Google Scholar

Dor-Shav, N. K. (1978). On the long-range effects of concentration camp internment on Nazi victims: 25 years later. Journal of Consulting and Clinical Psychology, 46, 1–11. doi:10.1037/0022-006X.46.1.1Google Scholar

Doucet, M., & Rovers, M. (2010). Generational trauma, attachment, and spiritual/religious interventions. Journal of Loss and Trauma, 15, 93–105. doi:10.1080/15325020903373078Google Scholar

Eitinger, L. (1961). Pathology of the concentration camp syndrome: Preliminary report. Archives of General Psychiatry, 5, 371–379. doi:10.1001/archpsyc.1961.01710160051006Google Scholar

Esmaeili, S. (2011). Intergenerational transmission of trauma: Traumatic impact on second-generation Armenian genocide survivors and its effects on parenting. San Francisco: Alliant International University, California School of Professional Psychology.Google Scholar

Evans-Campbell, T. (2008). Historical trauma in American Indian/Native Alaska communities: A multilevel framework for exploring impacts on individuals, families, and communities. Journal of Interpersonal Violence, 23, 316–338. doi:10.1177/0886260507312290Google Scholar

Eyerman, R. (2001). Cultural trauma: Slavery and the formation of African American identity. Cambridge: Cambridge University Press.Google Scholar

Faulk, C., & Dolinoy, D. C. (2011). Timing is everything: The when and how of environmentally induced changes in the epigenome of animals. Epigenetics, 6, 791–797. doi:10.4161/epi.6.7.16209Google Scholar

Field, N. P., Muong, S., & Sochanvimean, V. (2013). Parental styles in the intergenerational transmission of trauma stemming from the Khmer Rouge regime in Cambodia. American Journal of Orthopsychiatry, 83, 483–494. doi:10.1111/ajop.12057Google Scholar

Fowler, P. J., Tompsett, C. J., Braciszewski, J. M., Jacques-Tiura, A. J., & Baltes, B. B. (2009). Community violence: A meta-analysis on the effect of exposure and mental health outcomes of children and adolescents. Development and Psychopathology, 21, 227–259. doi:10.1017/S0954579409000145Google Scholar

Franklin, T. B., Russig, H., Weiss, I. C., Gräff, J., Linder, N., Michalon, A., … Mansuy, I. M. (2010). Epigenetic transmission of the impact of early stress across generations. Biological Psychiatry, 68, 408–415. doi:10.1016/j.biopsych.2010.05.036Google Scholar

Friedler, G. (1996). Paternal exposures: Impact on reproductive and developmental outcome. Pharmacology Biochemistry and Behavior, 55, 691–700. doi:10.1016/S0091-3057(96)00286-9Google Scholar

Galea, S., Nandi, A., & Vlahov, D. (2005). The epidemiology of post-traumatic stress disorder after disasters. Epidemiologic Reviews, 27, 78–91. doi:10.1093/epirev/mxi003Google Scholar

Galtung, J. (1990). Cultural violence. Journal of Peace Research, 27, 291–305. doi:10.1177/0022343390027003005Google Scholar

Gapp, K., Bohacek, J., Grossmann, J., Brunner, A. M., Manuella, F., Nanni, P., & Mansuy, I. M. (2016). Potential of environmental enrichment to prevent transgenerational effects of paternal trauma. Neuropsychopharmacology, 41, 2749–2758. doi:10.1038/npp.2016.87Google Scholar

Gapp, K., von Ziegler, L., Tweedie-Cullen, R. Y., & Mansuy, I. M. (2014). Early life epigenetic programming and transmission of stress-induced traits in mammals. Bioessays, 36, 491–502. doi:10.1002/bies.201300116Google Scholar

Gillman, M. W. (2005). Developmental origins of health and disease. New England Journal of Medicine, 353, 1848–1850. doi:10.1056/NEJMe058187Google Scholar

Glover, D. A., & Poland, R. E. (2002). Urinary cortisol and catecholamines in mothers of child cancer survivors with and without PTSD. Psychoneuroendocrinology, 27, 805–819. doi:10.1016/S0306-4530(01)00081-6Google Scholar

Goldberg, A. D., Allis, C. D., & Bernstein, E. (2007). Epigenetics: A landscape takes shape. Cell, 128, 635–638. doi:10.1016/j.cell.2007.02.006Google Scholar

Goldberg, R. (2015). Motherland: Growing up with the Holocaust: New York: New Press.Google Scholar

Gone, J. P. (2013). Redressing First Nations historical trauma: Theorizing mechanisms for indigenous culture as mental health treatment. Transcultural Psychiatry, 50, 683–706. doi:10.1177/1363461513487669Google Scholar

Gone, J. P., & Kirmayer, L. J. (2010). On the wisdom of considering culture and context in psychopathology. In Millon, T., Krueger, R. F., & Simonsen, E. (Eds.), Contemporary directions in psychopathology: Scientific foundations of the DSM-V and ICD-11 (pp. 72–96). New York: Guilford Press.Google Scholar

Hamad, M., Shelko, N., Kartarius, S., Montenarh, M., & Hammadeh, M. (2014). Impact of cigarette smoking on histone (H2B) to protamine ratio in human spermatozoa and its relation to sperm parameters. Andrology, 2, 666–677. doi:10.1111/j.2047-2927.2014.00245.xGoogle Scholar

Harper, L. (2005). Epigenetic inheritance and the intergenerational transfer of experience. Psychological Bulletin, 131, 340–360. doi:10.1037/0033-2909.131.3.340Google Scholar

Heard, E., & Martienssen, R. A. (2014). Transgenerational epigenetic inheritance: Myths and mechanisms. Cell, 157, 95–109. doi:10.1016/j.cell.2014.02.045Google Scholar

Heijmans, B. T., Tobi, E. W., Stein, A. D., Putter, H., Blauw, G. J., Susser, E. S., … Lumey, L. (2008). Persistent epigenetic differences associated with prenatal exposure to famine in humans. Proceedings of the National Academy of Sciences, 105, 17046–17049. doi:10.1073/pnas.0806560105Google Scholar

Hooker, D. A., & Czajkowski, A.P. (n.d.). Transforming historical harms. Manual published by Coming to the Table, a project of Eastern Mennonite University's Center for Justice and Peacebuilding. Harrisonburg, VA: Eastern Mennonite University.Google Scholar

Jablonka, E., & Raz, G. (2009). Transgenerational epigenetic inheritance: Prevalence, mechanisms, and implications for the study of heredity and evolution. Quarterly Review of Biology, 84, 131–176. doi:10.1086/598822Google Scholar

Jaenisch, R., & Bird, A. (2003). Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals. Nature Genetics, 33, 245–250. doi:10.1038/ng1089Google Scholar

Juster, R.-P., McEwen, B. S., & Lupien, S. J. (2010). Allostatic load biomarkers of chronic stress and impact on health and cognition. Neuroscience & Biobehavioral Reviews, 35, 2–16. doi:10.1016/j.neubiorev.2009.10.002.Google Scholar

Kaati, G., Bygren, L. O., Pembrey, M., & Sjöström, M. (2007). Transgenerational response to nutrition, early life circumstances and longevity. European Journal of Human Genetics, 15, 784–790. doi:10.1038/sj.ejhg.5201832Google Scholar

Karenian, H., Livaditis, M., Karenian, S., Zafiriadis, K., Bochtsou, V., & Xenitidis, K. (2011). Collective trauma transmission and traumatic reactions among descendants of Armenian refugees. International Journal of Social Psychiatry, 57, 327–337. doi:10.1177/0020764009354840Google Scholar

Kessler, R. C., Berglund, P., Demler, O., Jin, R., Merikangas, K. R., & Walters, E. E. (2005). Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Archives of General Psychiatry, 62, 593–602. doi:10.1001/archpsyc.62.6.593Google Scholar

Kessler, R. C., Sonnega, A., Bromet, E., Hughes, M., & Nelson, C. B. (1995). Posttraumatic stress disorder in the National Comorbidity Survey. Archives of General Psychiatry, 52, 1048–1060. doi:10.1001/archpsyc.1995.03950240066012Google Scholar

Kosten, T. R., Mason, J. W., Giller, E. L., Ostroff, R. B., & Harkness, L. (1987). Sustained urinary norepinephrine and epinephrine elevation in post-traumatic stress disorder. Psychoneuroendocrinology, 12, 13–20. doi:10.1016/0306-4530(87)90017-5Google Scholar

Leacock, E. B. (Ed.) (1971). The culture of poverty: A critique. New York: Simon and Schuster.Google Scholar

Lehrner, A., Bierer, L. M., Passarelli, V., Pratchett, L. C., Flory, J. D., Bader, H. N., … Makotkine, I. (2014). Maternal PTSD associates with greater glucocorticoid sensitivity in offspring of Holocaust survivors. Psychoneuroendocrinology, 40, 213–220. doi:10.1016/j.psyneuen.2013.11.019Google Scholar

Leon, G. R., Butcher, J. N., Kleinman, M., Goldberg, A., & Almagor, M. (1981). Survivors of the Holocaust and their children: Current status and adjustment. Journal of Personality and Social Psychology, 41, 503–516. doi:10.1037//0022-3514.41.3.503Google Scholar

Liberzon, I., Abelson, J. L., Flagel, S. B., Raz, J., & Young, E. A. (1999). Neuroendocrine and psychophysiologic responses in PTSD: A symptom provocation study. Neuropsychopharmacology, 21, 40–50. doi:10.1016/S0893-133X(98)00128-6Google Scholar

Lim, J. P., & Brunet, A. (2013). Bridging the transgenerational gap with epigenetic memory. Trends in Genetics, 29, 176–186. doi:10.1016/j.tig.2012.12.008Google Scholar

Linden, M., Baumann, K., Lieberei, B., Lorenz, C., & Rotter, M. (2011). Treatment of posttraumatic embitterment disorder with cognitive behaviour therapy based on wisdom psychology and hedonia strategies. Psychotherapy and Psychosomatics, 80, 199–205. doi:10.1159/000321580Google Scholar

Linden, M., & Rutkowski, K. (2013). Hurting memories and beneficial forgetting: Posttraumatic stress disorders, biographical developments, and social conflicts. London: Elsevier.Google Scholar

Martino, J. (1980). Collective memory of cultural trauma in Peru: Efforts to move from blame to reconciliation. In Yovanovich, G. & Huras, A. (Eds.), Latin American identities after 1980 (pp. 235–255). Waterloo: Wilfrid Laurier University Press.Google Scholar

Mason, J. W., Giller, E. L., Kosten, T. R., & Harkness, L. (1988). Elevation of urinary norepinephrine/cortisol ratio in posttraumatic stress disorder. Journal of Nervous and Mental Disease, 176, 498–502. doi:10.1097/00005053-198808000-00008Google Scholar

Mason, J. W., Giller, E. L., Kosten, T. R., Ostroff, R. B., & Podd, L. (1986). Urinary free-cortisol levels in posttraumatic stress disorder patients. Journal of Nervous and Mental Disease, 174, 145–149. doi:10.1097/00005053-198603000-00003Google Scholar

McEwen, B. S. (1998). Stress, adaptation, and disease: Allostasis and allostatic load. Annals of the New York Academy of Sciences, 840, 33–44. doi:10.1111/j.1749-6632.1998.tb09546.xGoogle Scholar

McEwen, B. S. (2012). Brain on stress: How the social environment gets under the skin. Proceedings of the National Academy of Sciences, 109(Suppl. 2), 17180–17185. doi:10.1073/pnas.1121254109Google Scholar

McEwen, B. S., & Wingfield, J. C. (2003). The concept of allostasis in biology and biomedicine. Hormones and Behavior, 43, 2–15. doi:10.1016/s0018-506x(02)00024-7Google Scholar

McGlothlin, E. H. (2006). Second-generation Holocaust literature: Legacies of survival and perpetration. Boston: Camden House.Google Scholar

McGowan, P. O., Sasaki, A., D'alessio, A. C., Dymov, S., Labonté, B., Szyf, M., … Meaney, M. J. (2009). Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nature Neuroscience, 12, 342–348. doi:10.1038/nn.2270Google Scholar

Meaney, M. J., Aitken, D. H., Bodnoff, S. R., Iny, L. J., & Sapolsky, R. M. (1985). The effects of postnatal handling on the development of the glucocorticoid receptor systems and stress recovery in the rat. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 9, 731–734. doi:10.1016/0278-5846(85)90050-8Google Scholar

Meaney, M. J., Aitken, D. H., Bodnoff, S. R., Iny, L. J., Tatarewicz, J. E., & Sapolsky, R. M. (1985). Early postnatal handling alters glucocorticoid receptor concentrations in selected brain regions. Behavioral Neuroscience, 99, 765–770. doi:10.1037/0735-7044.99.4.765Google Scholar

Meaney, M. J., Aitken, D. H., van Berkel, C., Bhatnagar, S., & Sapolsky, R. M. (1988). Effect of neonatal handling on age-related impairments associated with the hippocampus. Science, 239(4841, Pt. 1), 766–768. doi:10.1126/science.3340858Google Scholar

Mendeloff, D. (2009). Trauma and vengeance: Assessing the psychological and emotional effects of post-conflict justice. Human Rights Quarterly, 31, 592–623. doi:10.1353/hrq.0.0100Google Scholar

Miller, G. (2010). The seductive allure of behavioral epigenetics. Science, 329, 24–27. doi:10.1126/science.329.5987.24Google Scholar

Mohatt, N. V., Thompson, A. B., Thai, N. D., & Tebes, J. K. (2014). Historical trauma as public narrative: A conceptual review of how history impacts present-day health. Social Science & Medicine, 106, 128–136. doi:10.1016/j.socscimed.2014.01.043Google Scholar

Moon, C. (2009). Healing past violence: Traumatic assumptions and therapeutic interventions in war and reconciliation. Journal of Human Rights, 8, 71–91. doi:10.1080/14754830902717726Google Scholar

Morris, M. C., Compas, B. E., & Garber, J. (2012). Relations among posttraumatic stress disorder, comorbid major depression, and HPA function: A systematic review and meta-analysis. Clinical Psychology Review, 32, 301–315. doi:10.1016/j.cpr.2012.02.002Google Scholar

Mulligan, C., D'Errico, N., Stees, J., & Hughes, D. (2012). Methylation changes at NR3C1 in newborns associate with maternal prenatal stress exposure and newborn birth weight. Epigenetics, 7, 853–857. doi:10.4161/epi.21180Google Scholar

Münyas, B. (2008). Genocide in the minds of Cambodian youth: Transmitting (hi) stories of genocide to second and third generations in Cambodia. Journal of Genocide Research, 10, 413–439. doi:10.1080/14623520802305768Google Scholar

Niederland, W. G. (1981). The survivor syndrome: Further observations and dimensions. Journal of the American Psychoanalytic Association, 29, 413–425. doi:10.1177/000306518102900207Google Scholar

Nugent, B. M., & Bale, T. L. (2015). The omniscient placenta: Metabolic and epigenetic regulation of fetal programming. Frontiers in Neuroendocrinology, 39, 28–37. doi:10.1016/j.yfrne.2015.09.001Google Scholar

Oberlander, T. F., Weinberg, J., Papsdorf, M., Grunau, R., Misri, S., & Devlin, A. M. (2008). Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses. Epigenetics, 3, 97–106. doi:10.4161/epi.3.2.6034Google Scholar

O'Nell, T. D. (1996). Disciplined hearts: History, identity, and depression in an American Indian community. Berkeley, CA: University of California Press.Google Scholar

Ouko, L. A., Shantikumar, K., Knezovich, J., Haycock, P., Schnugh, D. J., & Ramsay, M. (2009). Effect of alcohol consumption on CpG methylation in the differentially methylated regions of H19 and IG-DMR in male gametes—Implications for fetal alcohol spectrum disorders. Alcoholism: Clinical and Experimental Research, 33, 1615–1627. doi:10.1111/j.1530-0277.2009.00993.xGoogle Scholar

Painter, R. C., Osmond, C., Gluckman, P., Hanson, M., Phillips, D. I., & Roseboom, T. J. (2008). Transgenerational effects of prenatal exposure to the Dutch famine on neonatal adiposity and health in later life. British Journal of Obstetrics and Gynaecology, 115, 1243–1249. doi:10.1111/j.1471-0528.2008.01822.xGoogle Scholar

Pembrey, M. E., Bygren, L. O., Kaati, G., Edvinsson, S., Northstone, K., Sjöström, M., & Golding, J. (2006). Sex-specific, male-line transgenerational responses in humans. European Journal of Human Genetics, 14, 159–166. doi:10.3109/14647273.2010.524721Google Scholar

Perroud, N., Rutembesa, E., Paoloni-Giacobino, A., Mutabaruka, J., Mutesa, L., Stenz, L., … Karege, F. (2014). The Tutsi genocide and transgenerational transmission of maternal stress: Epigenetics and biology of the HPA axis. World Journal of Biological Psychiatry, 15, 334–345. doi:10.3109/15622975.2013.866693Google Scholar

Pihama, L., Reynolds, P., Smith, C., Reid, J., Smith, L. T., & Nana, R. T. (2014). Positioning historical trauma theory within Aotearoa New Zealand. AlterNative, 10, 248–262. doi:10.1177/117718011401000304Google Scholar

Prager, J. (2003). Lost childhood, lost generations: The intergenerational transmission of trauma. Journal of Human Rights, 2, 173–181. doi:10.1080/1475483032000078161Google Scholar

Radomislensky, I., & Shemesh, A. A. (2007). Psychopathology and other health dimensions among the offspring of Holocaust survivors: Results from the Israel National Health Survey. Israel Journal of Psychiatry and Related Sciences, 44, 144–151.Google Scholar

Radtke, K. M., Ruf, M., Gunter, H. M., Dohrmann, K., Schauer, M., Meyer, A., & Elbert, T. (2011). Transgenerational impact of intimate partner violence on methylation in the promoter of the glucocorticoid receptor. Translational Psychiatry, 1, e21. doi:10.1038/tp.2011.21Google Scholar

Raphael, B., Swan, P., & Martinek, N. (1998). Intergenerational aspects of trauma for Australian Aboriginal people. In Danieli, Y. (Ed.), International handbook of multigenerational legacies of trauma (pp. 327–339). New York: Plenun Press.Google Scholar

Ravelli, G.-P., Stein, Z. A., & Susser, M. W. (1976). Obesity in young men after famine exposure in utero and early infancy. New England Journal of Medicine, 295, 349–353. doi:10.1056/NEJM197608122950701Google Scholar

Rodgers, A. B., Morgan, C. P., Bronson, S. L., Revello, S., & Bale, T. L. (2013). Paternal stress exposure alters sperm microRNA content and reprograms offspring HPA stress axis regulation. Journal of Neuroscience, 33, 9003–9012. doi:10.1523/JNEUROSCI.0914-13.2013Google Scholar

Rosenheck, R. (1986). Impact of posttraumatic stress disorder of World War II on the next generation. Journal of Nervous and Mental Disease, 174, 319–327. doi:10.1097/00005053-198606000-00001Google Scholar

Roth, M., Neuner, F., & Elbert, T. (2014). Transgenerational consequences of PTSD: Risk factors for the mental health of children whose mothers have been exposed to the Rwandan genocide. International Journal of Mental Health Systems, 8, 12. doi:10.1186/1752-4458-8-12Google Scholar

Ryan, W. (1976). Blaming the victim. New York: Random House.Google Scholar

Santarelli, S., Lesuis, S. L., Wang, X.-D., Wagner, K. V., Hartmann, J., Labermaier, C., … Schmidt, M. V. (2014). Evidence supporting the match/mismatch hypothesis of psychiatric disorders. European Neuropsychopharmacology, 24, 907–918. doi:10.1016/j.euroneuro.2014.02.002Google Scholar

Schagdarsurengin, U., & Steger, K. (2016). Epigenetics in male reproduction: Effect of paternal diet on sperm quality and offspring health. Nature Reviews Urology, 13, 584–595. doi:10.1038/nrurol.2016.157Google Scholar

Schmidt, M. V. (2011). Animal models for depression and the mismatch hypothesis of disease. Psychoneuroendocrinology, 36, 330–338. doi:10.1016/j.psyneuen.2010.07.001Google Scholar

Schwab, G. (2010). Haunting legacies: Violent histories and transgenerational trauma. New York: Columbia University Press.Google Scholar

Shrira, A., Palgi, Y., Ben-Ezra, M., & Shmotkin, D. (2011). Transgenerational effects of trauma in midlife: Evidence for resilience and vulnerability in offspring of Holocaust survivors. Psychological Trauma: Theory, Research, Practice, and Policy, 3, 394–402. doi:10.1037/a0020608Google Scholar

Smith, S. M., & Vale, W. W. (2006). The role of the hypothalamic-pituitary-adrenal axis in neuroendocrine responses to stress. Dialogues in Clinical Neuroscience, 8, 383–395.Google Scholar

Solkoff, N. (1981). Children of survivors of the Nazi Holocaust: A critical review of the literature. American Journal of Orthopsychiatry, 51, 29–42. doi:10.1111/j.1939-0025.1981.tb01345.xGoogle Scholar

Solomon, Z., Kotler, M., & Mikulincer, M. (1988). Combat-related posttraumatic stress disorder among second-generation Holocaust survivors: Preliminary findings. American Journal of Psychiatry, 145, 865–868. doi:10.1176/ajp.145.7.865Google Scholar

Sorel, E. (2010). The WHO World Mental Health Surveys: Global perspectives on the epidemiology of mental disorders: American Psychiatric Association, 167, 354–355. doi:10.1176/appi.ajp.2009.09081218Google Scholar

Spiegelman, A. (2003). The complete maus. London: Penguin Books Limited.Google Scholar

Steel, Z., Silove, D., Phan, T., & Bauman, A. (2002). Long-term effect of psychological trauma on the mental health of Vietnamese refugees resettled in Australia: A population-based study. Lancet, 360, 1056–1062. doi:10.1016/s0140-6736(02)11142-1Google Scholar

Steinitz, L. Y. (1982). Psycho-social effects of the Holocaust on aging survivors and their families. Journal of Gerontological Social Work, 4, 145–152. doi:10.1300/j083v04n03_13Google Scholar

Sullivan, P. (1986). The generation of cultural trauma: What are anthropologists for? Australian Aboriginal Studies, 1, 13–23.Google Scholar

Svob, C., Brown, N. R., Takšić, V., Katulić, K., & Žauhar, V. (2016). Intergenerational transmission of historical memories and social-distance attitudes in post-war second-generation Croatians. Memory & Cognition, 44, 846–855. doi:10.3758/s13421-016-0607-xGoogle Scholar

Tedeschi, R. G., & Calhoun, L. G. (2004). Posttraumatic growth: Conceptual foundations and empirical evidence. Psychological Inquiry, 15, 1–18. doi:10.1207/s15327965pli1501_01Google Scholar

Tobi, E. W., Slieker, R. C., Luijk, R., Dekkers, K. F., Stein, A. D., Xu, K. M., … Heijmans, B. T. (2018). DNA methylation as a mediator of the association between prenatal adversity and risk factors for metabolic disease in adulthood. Science Advances, 4, 1–10. doi:10.1126/sciadv.aao4364Google Scholar

Tyrka, A. R., Parade, S. H., Eslinger, N. M., Marsit, C. J., Lesseur, C., Armstrong, D. A., … Seifer, R. (2015). Methylation of exons 1D, 1F, and 1H of the glucocorticoid receptor gene promoter and exposure to adversity in preschool-aged children. Development and Psychopathology, 27, 577–585. doi:10.1017/S095457941500017Google Scholar

Tyrka, A. R., Parade, S. H., Welch, E. S., Ridout, K. K., Price, L. H., Marsit, C., … Carpenter, L. L. (2016). Methylation of the leukocyte glucocorticoid receptor gene promoter in adults: Associations with early adversity and depressive, anxiety and substance-use disorders. Translational Psychiatry, 6, e848. doi:10.1038/tp.2016.112Google Scholar

Tyrka, A. R., Price, L. H., Marsit, C., Walters, O. C., & Carpenter, L. L. (2012). Childhood adversity and epigenetic modulation of the leukocyte glucocorticoid receptor: Preliminary findings in healthy adults. PLOS ONE, 7, e30148. doi:10.1371/journal.pone.0030148Google Scholar

van IJzendoorn, M. H., Bakermans-Kranenburg, M. J., & Sagi-Schwartz, A. (2003). Are children of Holocaust survivors less well-adapted? A meta-analytic investigation of secondary traumatization. Journal of Traumatic Stress, 16, 459–469. doi:10.1023/A:1025706427300Google Scholar

Veenendaal, M. V., Painter, R. C., Rooij, S., Bossuyt, P. M., Post, J., Gluckman, P. D., … Roseboom, T. J. (2013). Transgenerational effects of prenatal exposure to the 1944–45 Dutch famine. BJOG: International Journal of Obstetrics & Gynaecology, 120, 548–554. doi:10.1111/j.1471-0528.2009.02108.xGoogle Scholar

Volkan, V. D. (2001). Transgenerational transmissions and chosen traumas: An aspect of large-group identity. Group Analysis, 34, 79–97. doi:10.1177/05333160122077730Google Scholar

Weaver, I. C. (2007). Epigenetic programming by maternal behavior and pharmacological intervention. Nature versus nurture: Let's call the whole thing off. Epigenetics, 2, 22–28. doi:10.4161/epi.2.1.3881Google Scholar

Weaver, I. C., Cervoni, N., Champagne, F. A., D'Alessio, A. C., Sharma, S., Seckl, J. R., … Meaney, M. J. (2004). Epigenetic programming by maternal behavior. Nature Neuroscience, 7, 847–854. doi:10.1038/nn1276Google Scholar

Widom, C. S. (1989). Does violence beget violence? A critical examination of the literature. Psychological Bulletin, 106, 3–28. doi:10.1037//0033-2909.106.1.3Google Scholar

Wright, S. E. (1993). Blaming the victim, blaming society or blaming the discipline: Fixing responsibility for poverty and homelessness. Sociological Quarterly, 34, 1–16. doi:10.1111/j.1533-8525.1993.tb00127.xGoogle Scholar

Yahyavi, S. T., Zarghami, M., Naghshvar, F., & Danesh, A. (2015). Relationship of cortisol, norepinephrine, and epinephrine levels with war-induced posttraumatic stress disorder in fathers and their offspring. Revista Brasileira de Psiquiatria, 37, 93–98. doi:10.1590/1516-4446-2014-1414Google Scholar

Yehuda, R. (2009). Status of glucocorticoid alterations in post-traumatic stress disorder. Annals of the New York Academy of Sciences, 1179, 56–69. doi:10.1111/j.1749-6632.2009.04979.xGoogle Scholar

Yehuda, R., Bierer, L. M., Andrew, R., Schmeidler, J., & Seckl, J. R. (2009). Enduring effects of severe developmental adversity, including nutritional deprivation, on cortisol metabolism in aging Holocaust survivors. Journal of Psychiatric Research, 43, 877–883. doi:10.1016/j.jpsychires.2008.12.003Google Scholar

Yehuda, R., Bierer, L. M., Schmeidler, J., Aferiat, D. H., Breslau, I., & Dolan, S. (2000). Low cortisol and risk for PTSD in adult offspring of holocaust survivors. American Journal of Psychiatry, 157, 1252–1259. doi:10.1176/appi.ajp.157.8.1252Google Scholar

Yehuda, R., Blair, W., Labinsky, E., & Bierer, L. M. (2007). Effects of parental PTSD on the cortisol response to dexamethasone administration in their adult offspring. American Journal of Psychiatry, 164, 163–166. doi:10.1176/ajp.2007.164.1.163Google Scholar

Yehuda, R., Boisoneau, D., Mason, J. W., & Giller, E. L. (1993). Glucocorticoid receptor number and cortisol excretion in mood, anxiety, and psychotic disorders. Biological Psychiatry, 34, 18–25. doi:10.1016/0006-3223(93)90252-9Google Scholar

Yehuda, R., Daskalakis, N. P., Lehrner, A., Desarnaud, F., Bader, H. N., Makotkine, I., … Meaney, M. J. (2014). Influences of maternal and paternal PTSD on epigenetic regulation of the glucocorticoid receptor gene in Holocaust survivor offspring. American Journal of Psychiatry, 171, 872–880. doi:10.1176/appi.ajp.2014.13121571Google Scholar

Yehuda, R., Engel, S. M., Brand, S. R., Seckl, J., Marcus, S. M., & Berkowitz, G. S. (2005). Transgenerational effects of posttraumatic stress disorder in babies of mothers exposed to the World Trade Center attacks during pregnancy. Journal of Clinical Endocrinology & Metabolism, 90, 4115–4118. doi:10.1210/jc.2005-0550Google Scholar

Yehuda, R., Flory, J. D., Bierer, L. M., Henn-Haase, C., Lehrner, A., Desarnaud, F., … Meaney, M. J. (2015). Lower methylation of glucocorticoid receptor gene promoter 1F in peripheral blood of veterans with posttraumatic stress disorder. Biological Psychiatry, 77, 356–364. doi:10.1016/j.biopsych.2014.02.006Google Scholar

Yehuda, R., Golier, J. A., Yang, R.-K., & Tischler, L. (2004). Enhanced sensitivity to glucocorticoids in peripheral mononuclear leukocytes in posttraumatic stress disorder. Biological Psychiatry, 55, 1110–1116. doi:10.1016/s0006-3223(04)00188-xGoogle Scholar

Yehuda, R., Halligan, S. L., & Bierer, L. M. (2002). Cortisol levels in adult offspring of Holocaust survivors: Relation to PTSD symptom severity in the parent and child. Psychoneuroendocrinology, 27, 171–180. doi:10.1016/s0306-4530(01)00043-9Google Scholar

Yehuda, R., Halligan, S. L., Grossman, R., Golier, J. A., & Wong, C. (2002). The cortisol and glucocorticoid receptor response to low dose dexamethasone administration in aging combat veterans and holocaust survivors with and without posttraumatic stress disorder. Biological Psychiatry, 52, 393–403. doi:10.1016/s0006-3223(02)01357-4Google Scholar

Yehuda, R., Kahana, B., Binder-Brynes, K., & Southwick, S. M. (1995). Low urinary cortisol excretion in Holocaust survivors with posttraumatic stress disorder. American Journal of Psychiatry, 152, 982. doi:10.1176/ajp.152.7.982Google Scholar

Yehuda, R., Kahana, B., Schmeidler, J., & Southwick, S. M. (1995). Impact of cumulative lifetime trauma and recent stress on current posttraumatic stress disorder symptoms in Holocaust survivors. American Journal of Psychiatry, 152, 1815–1818. doi:10.1176/ajp.152.12.1815Google Scholar

Yehuda, R., & Lehrner, A. (2018). Intergenerational transmission of trauma effects: Putative role of epigenetic mechanisms. World Psychiatry, 17, 243–257. doi:10.1002/wps.20568.Google Scholar

Yehuda, R., Lehrner, A., & Bierer, L. M. (2018). The public reception of putative epigenetic mechanisms in the transgenerational effects of trauma. Environmental Epigenetics, 4, 1–7. doi:10.1093/eep/dvy018.Google Scholar

Yehuda, R., Lowy, M. T., Southwick, S. M., Shaffer, D., & Giller, E. L. Jr. (1991). Lymphocyte glucocorticoid receptor number in posttraumatic stress disorder. American Journal of Psychiatry, 148, 499–504. doi:10.1176/ajp.148.4.499Google Scholar

Yehuda, R., & McFarlane, A. (1995). Conflict between current knowledge about posttraumatic stress disorder and its original conceptual basis. American Journal of Psychiatry, 152, 1705–1713. doi:10.1176/ajp.152.12.1705Google Scholar

Yehuda, R., McFarlane, A., & Shalev, A. (1998). Predicting the development of posttraumatic stress disorder from the acute response to a traumatic event. Biological Psychiatry, 44, 1305–1313. doi:10.1016/s0006-3223(98)00276-5Google Scholar

Yehuda, R., Morris, A., Labinsky, E., Zemelman, S., & Schmeidler, J. (2007). Ten-year follow-up study of cortisol levels in aging holocaust survivors with and without PTSD. Journal of Traumatic Stress, 20, 757–761. doi:10.1002/jts.20228Google Scholar

Yehuda, R., Schmeidler, J., Siever, L. J., Binder-Brynes, K., & Elkin, A. (1997). Individual differences in posttraumatic stress disorder symptom profiles in Holocaust survivors in concentration camps or in hiding. Journal of Traumatic Stress, 10, 453–463. doi:10.1002/jts.2490100310Google Scholar

Yehuda, R., Schmeidler, J., Wainberg, M., Binder-Brynes, K., & Duvdevani, T. (1998). Vulnerability to posttraumatic stress disorder in adult offspring of Holocaust survivors. American Journal of Psychiatry, 155, 1163–1171. doi:10.1176/ajp.155.9.1163Google Scholar

Yehuda, R., Siever, L. J., Teicher, M. H., Levengood, R. A., Gerber, D. K., Schmeidler, J., & Yang, R.-K. (1998). Plasma norepinephrine and 3-methoxy-4-hydroxyphenylglycol concentrations and severity of depression in combat posttraumatic stress disorder and major depressive disorder. Biological Psychiatry, 44, 56–63. doi:10.1016/s0006-3223(98)80007-3Google Scholar

Yehuda, R., Southwick, S. M., Giller, E. L., Ma, X., & Mason, J. W. (1992). Urinary catecholamine excretion and severity of PTSD symptoms in Vietnam combat veterans. Journal of Nervous and Mental Disease, 180, 321–325. doi:10.1097/00005053-199205000-00006Google Scholar

Yehuda, R., Southwick, S. M., Krystal, J. H., Bremner, D., Charney, D. S., & Mason, J. W. (1993). Enhanced suppression of cortisol following dexamethasone administration in posttraumatic stress disorder. American Journal of Psychiatry, 150, 83. doi:10.1176/ajp.150.1.83Google Scholar

Yehuda, R., Southwick, S. M., Nussbaum, G., Wahby, V. S., Giller, E. L., & Mason, J. W. (1990). Low urinary cortisol excretion in patients with posttraumatic stress disorder. Journal of Nervous and Mental Disease, 35, 710–711. doi:10.1016/0006-3223(94)91000-6Google Scholar

Yehuda, R., Teicher, M. H., Seckl, J. R., Grossman, R. A., Morris, A., & Bierer, L. M. (2007). Parental posttraumatic stress disorder as a vulnerability factor for low cortisol trait in offspring of holocaust survivors. Archives of General Psychiatry, 64, 1040–1048. doi:10.1001/archpsyc.64.9.1040Google Scholar

Yehuda, R., Teicher, M. H., Trestman, R. L., Levengood, R. A., & Siever, L. J. (1996). Cortisol regulation in posttraumatic stress disorder and major depression: A chronobiological analysis. Biological Psychiatry, 40, 79–88. doi:10.1016/0006-3223(95)00451-3Google Scholar

Young, E. A., & Breslau, N. (2004). Cortisol and catecholamines in posttraumatic stress disorder: An epidemiologic community study. Archives of General Psychiatry, 61, 394–401. doi:10.1001/archpsyc.61.4.394Google Scholar