Recycling of H1N1 influenza A virus in man — a haemagglutinin antibody study | Epidemiology & Infection | Cambridge Core (original) (raw)

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Sera from people born between 1883 and 1930 and collected in 1977 were tested for the presence of HI antibodies to A/FM/1/47 (H1N1) virus and three recently (1977 and 1978) isolated influenza A-H1N1 viruses. The highest frequency of high-titred antibody to the four H1N1 viruses was detected in sera from people born in 1903–4, i.e. 42,54,38, and 22% had antibody against A/FM/1/47, A/Hong Kong/117/77, A/Brazil/11/78, and A/Fukushima/103/78 respectively. The birthdate groups 1896–1907 showed a higher percentage of HI antibody titres ≥18, ≥50, ≥100 or ≥1600 against the four H1N1 viruses than the birthdate groups 1907–30. This indicates the existence of an era, 1908–18, in which, apart from the H3N2 virus (1900–18), the H1N1 virus was epidemic among the human population.

Type

Research Article

Copyright

Copyright © Cambridge University Press 1983

References

Davenport, F. M., Minuse, E., Hennessy, A. V. & Francis, T. Jr. (1969). Interpretations of influenza antibody patterns of man. Bulletin of the World Health Organization 41, 453–460.Google Scholar

Francis, T. Jr., Davenport, F. M. & Hennessy, A. V. (1953). A serologic recapitulation of human infection with different strains of influenza virus. Transactions of the Association of American Physicians 66, 231–239.Google Scholar

Fukumi, H. (1969). Interpretation of influenza antibody patterns in man. Existence and significance of Hong Kong antibody in old people prior to the Hong-Kong influenza epidemic. Bulletin of the World Health Organzation 41, 469–473.Google Scholar

Masurel, N. (1962). Studies on the Content of Haemagglutination Inhibiting Antibody for Swine Influenza Virus A in Sera from People Living in The Netherlands in 1957–1958. Thesis, University of Leyden.Google Scholar

Masurel, N. (1969 a). Serological characteristics of a ‘new’ serotype of influenza A virus: the Hong Kong strain. Bulletin of the World Health Organization 41, 461–468.Google Scholar

Masurel, N. (1969 b). Relation between Hong Kong virus and former human A2 isolates and the A/Equi 2 virus in human sera collected before 1957. Lancet i, 907–910.CrossRefGoogle Scholar

Masurel, N. (1976). Swine influenza virus and the recycling of influenza-A viruses in man Lancet ii, 244–247.CrossRefGoogle Scholar

Masurel, N. & André, F. E. (1978). Antibody response against current H1N1 influenza virus after vaccination with last season's trivalent vaccine. Lancet i, 144–145.CrossRefGoogle Scholar

Masurel, N. & Marine, W. M. (1973). Recycling of Asian and Hong Kong influenza A virus hemagglutinins in man. American Journal of Epidemiology 97, 44–49.Google Scholar

Monto, A. S. & Maassab, H. F. (1981). Serologic responses to non-prevalent influenza A viruses during intercyclic periods. American Journal of Epidemiology 112, 236–244.CrossRefGoogle Scholar

Mulder, J. & Masurel, N. (1958). Pre-epidemic antibody against 1957 strain of Asiatic influenza in serum of older people living in The Netherlands. Lancet i, 810–814.CrossRefGoogle Scholar

Rekart, M., Rupnik, K., Cesario, T. C. & Tilles, J. G.. (1982). Prevalence of hemagglutination inhibition antibody to current strains of the H3N2 and H1N1 subtypes of influenza A virus in sera collected from the elderly in 1976. American Journal of Epidemiology 115,587–597.CrossRefGoogle ScholarPubMed