Epithelial Cell Plasticity in Development and Tumor Progression (original) (raw)
References
Lengauer C, Kinzler KW, Vogelstein B: Genetic instabilities in human cancers. Nature 396: 643–649, 1998 Google Scholar
Shackney SE, Shankey TV: Common patterns of genetic evolution in human solid tumors. Cytometry 29: 1–27, 1997 Google Scholar
Fagnou C, Michon J, Peter M, Oberlin O, Zucker JM, Magdelenat H, Delattre O: Presence of tumor cells in bone marrow but not in blood is associated with adverse prognosis in patients with Ewing's tumor. J Clin Invest 16: 1707–1711, 1998 Google Scholar
Thibodeau SN, Bren G, Shaid D: Micro satellite instability in cancer of the proximal colon. Science 260: 816–819, 1993 Google Scholar
Lothe A, Peltomäki P, Meling GI, Aaltonen LA, Nyström-Lahti M et al.: Genomic instability in colorectal cancer: relationship to clinicopathological variables and family history. Cancer Res 53: 5849–5852, 1993 Google Scholar
Kochhar R, Hailing KC, McDonnell S, Shaid DJ, French AM, O'Connell MJ, Nagorney DM, Thibodeau SN: Allelic imbalance and microsatellite instability in resected Duke's colorectal cancer. Diagnost Mol Pathol 6: 78–84, 1997 Google Scholar
Ogunbiyi OA, Goodfellow PJ, Herfarth K, Gagliardi G, Swanson PE, Binbaum EH, Read TE, Fleshman JW, Kodner IJ, Moley JF: Confirmation that chromosome 18q allelic loss in colon cancer is a prognostic indicator. J Clin Onc 16: 427–433, 1998 Google Scholar
Carethers JM, Hawn MT, Greenson JK, Hitchcock CL, Boland CR: Prognostic significance of allelic loss at chromosome 18q21 for stage II colorectal cancer. Gastroenterology 114: 1188–1195, 1998 Google Scholar
Folkman J: New perspectives in clinical oncology from angiogenesis research. Eur J Cancer 32A: 2534–2539, 1996 Google Scholar
Fox SB: Tumor angiogenesis and prognosis. Histopathology 30: 294–301, 1997 Google Scholar
Viens P, Pernault-Llorca F, Jacquemier J, Gravis C, Cowen D, Bertucci F, Houvenaeghel G, Blaise D, Maraninchi D: High dose chemotherapy and haematopoietic stem cell transplantation for inflammmatory breast cancer: pathologic response and outcome. Bone Marrow Transplantation 21: 249–254, 1998 Google Scholar
Kinzler KW, Vogelstein B: Landscaping the cancer terrain. Science 280: 1036–1037, 1998 Google Scholar
Watson KL, Justice RW, Bryant P: Drosophila in cancer research: the first fifty tumor suppressor genes. Development 18: 19–33, 1994 Google Scholar
Gilbert SF: Developmental Biology. Fifth edition. Massachusetts Sinauer Associates Inc. Publishers, Sunderland, 1997 Google Scholar
Jouanneau J, Tucker GC, Boyer B, Valleś AM, Thiery JP: Epithelial cell plasticity in neoplasia. Cancer Cells 3: 525–529, 1991 Google Scholar
Savagner P, Boyer B, Valles AM, Jouanneau J, Thiery IP: Modulations of the epithelial phenotype during embryogenesis and cancer progression. In: Dickson R, Lipmann M (eds) Mammary tumorigenesis and malignant progression. Kluwer Academic Publishers, Dordrecht, The Netherlands, 1994, pp 229–249 Google Scholar
Birchmeier C, Birchmeier W, Brand-Saberi B: Epithelial-mesenchymal transitions in cancer progression. Acta Anat 156: 217–226, 1996 Google Scholar
Leptin M, Casal J, Grunewald B, Reuter R: Mechanisms of early Drosophila mesoderm formation. In: Stern CD, Ingham PW (eds) Gastrulation. The Company of Biologists, 1992, pp 23–31
Morize P, Christiansen AE, Costa M, Parks S, Wieschaus E: Hyperactivation of the folded gastrulation pathway induces specific cell shape changes. Development 125: 589–597, 1998 Google Scholar
Hacker U, Perrimon N: DRhoGEF2 encodes a member of the Dbl family of oncogenes and controls cell shape changes during gastrulation in Drosophila. Genes & Development 12: 274–284, 1998 Google Scholar
Keller R: Early embryonic development of Xenopus laevis. In: Kay KB, Peng BH (eds) Methods in Cell Biology. Xenopus laevis: practical uses in Cell and Molecular Biology. Academic Press, 1991, pp 61–113
Niehrs C, Keller R, Cho KWY, De Robertis EM: The homeobox gene goosecoid controls cell migration in xenopus embryos. Cell 72: 491–503, 1993 Google Scholar
Pannese M, Polo C, Andreazzoli M, Vignali R, Kablar B, Barsacchi G, Boncinelli E: The Xenopus homologue of Otx2 is a maternal homeobox gene that demarcates and specifies anterior body regions. Development 121: 707–720, 1995 Google Scholar
Broders F, Thiery JP: Contribution of cadherins to directional cell migration and histogenesis in xenopus embryos. Cell Adh Com 3: 419–440, 1995 Google Scholar
Kim S-H, Yamamoto A, Bouwmeester T, Agius E, De Robertis EM: The role of paraxial protocadherin in selective adhesion and cell movements of the mesoderm during Xenopus gastrulation. Development 125: 4681–4691, 1998 Google Scholar
Le Douarin N: The Neural Crest. Cambridge University Press, 1982.
Thiery JP, Duband JL, Dufour S: Adhesion systems in morphogenesis and cell migration during avian embryogenesis. In: Morphoregulatory Molecules. John Wiley and Sons, New York, 1990, pp 597–625 Google Scholar
Duband JL, Monier F, Delannet M, Newgreen D: Epithelium-mesenchyme transition during neural crest development. Acta Anat 154: 63–78, 1996 Google Scholar
Nieto AM, Sargent MC, Wilkinson DG, Cooke J: Control of cell behavior during vertebrate development by Slug, a zinc finger gene. Science 264: 835–839, 1994 Google Scholar
Mancilla A, Mayor R: Neural crest formation in Xenopus laevis: mechanisms of Xslug induction. Dev Biol 177: 580–589, 1996 Google Scholar
Glazer L, Shilo B-Z: The Drosophila FGF-R homolog is expressed in the embryonic tracheal system and appears to be required for directed tracheal cell expension. Gene Dev 5: 697–705, 1991 Google Scholar
Hacohen N, Kramer S, Sutherland D, Hiromi Y, Krasnow D: Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways. Cell 92: 253–263, 1998 Google Scholar
Bellusci S, Grindley J, Emoto H, Itoh N, Hogan BL: Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung. Development 124: 4867–4878, 1997 Google Scholar
Peters K, Werner S, Liao X, Wert S, Whitsett J, Williams L: Targeted expression of a dominant negative FGF receptor blocks branching morphogenesis and epithelial differentiation of the mouse lung. EMBO J 13: 3296–3301, 1994 Google Scholar
Niemann C, Brinkmann V, Spitzer E, Hartmann G, Sachs M, Naundorf H, Birchmeier W: Reconstitution of mammary gland development in vitro: requirement of c-met and c-erbB2 signaling for branching and alveolar morphogenesis. J Cell Biol 143: 533–545, 1998 Google Scholar
Boccaccio C, Ando M, Tamagnone L, Bardelli A, Michieli P, Battistini C, Comoglio PM: Induction of epithelial tubules by growth factor HGF depends on the STAT pathway. Nature 391: 285–288, 1998 Google Scholar
Tchao R: Novel forms of epithelial cell motility on collagen and on glass surfaces. Cell Motil 4: 333–341, 1982 Google Scholar
Boyer B, Tucker GC, Vallés AM, Gavrilovic J, Thiery JP: Reversible transition towards a fibroblastic phenotype in a rat carcinoma cell line. Int J Cancer 4: 69–75, 1989 Google Scholar
Vallés AM, Tucker G, Thiery JP, Boyer B: Alternative patterns of mitogenesis and cell scattering induced by acidic FGF as a function of cell density in a rat bladder carcinoma cell line. Cell Regulation 4: 975–988, 1990 Google Scholar
Vallés AM, Boyer B, Tucker GC, Badet J, Barritault D, Thiery JP: Acidic fibroblast growth factor is a modulator of epithelial plasticity in a rat bladder carcinoma cell line. Proc Natl Acad Sci USA 87: 1124–1128, 1990 Google Scholar
Gavrilovic J, Moens G, Thiery JP, Jouanneau J: Expression of TGF_α_ induces a motile fibroblast-like phenotype with extracellular matrix-degrading potential in a rat bladder carcinoma cell line. Cell Regulation 1: 1003–1014, 1990 Google Scholar
Bellusci S, Moens G, Gaudino G, Comoglio P, Nakamura T, Thiery JP, Jouanneau J: Creation of an hepatocyte growth factor/scatter factor autocrine loop in carcinoma cells induces invasive properties associated with increased oncogenic potential. Oncogene 9: 1091–1099, 1994 Google Scholar
Boyer B, Valles AM, Thiery JP: Model systems of epithelium-mesenchyme transition. Acta Anat 156: 227–239, 1996 Google Scholar
Savagner P, Vallés AM, Jouanneau J, Yamada K, Thiery JP: Alternative splicing in Fibroblast Growth Factor receptor 2 is associated with induced epithelial-mesenchymal transition in rat bladder carcinoma cells. Mol Biol Cell 5: 851–862, 1994 Google Scholar
Boyer B, Dufour S, Thiery JP: E-cadherin expression during the acidic FGF-induced dispersion of a rat bladder carcinoma cell line. Exp Cell Res 201: 347–357, 1992 Google Scholar
Boyer B, Thiery JP: Cyclic AMP Distinguishes between two functions of acidic FGF in a rat bladder carcinoma cell line. J Cell Biol 120: 767–776, 1993 Google Scholar
Rodier JM, Valles AM, Denoyelle M, Thiery JP, Boyer B: pp60c-Src is a positive regulator of growth factor-induced cell scattering in a rat bladder carcinoma cell line. J Cell Biol 131: 761–773, 1995 Google Scholar
Boyer B, Roche S, Denoyelle M, Thiery JP: Src and ras are involved in separate pathways in epithelial cell scattering. EMBO J 16: 5904–5943, 1997 Google Scholar
Savagner P, Yamada KM, Thiery JP: The zinc-finger protein slug causes desmosome dissociation, an initial and necessary step for growth factor-induced epithelial-mesenchymal transition. J Cell Biol 137: 1403–1419, 1997 Google Scholar
Tucker GC, Delouvée A, Jouanneau J, Gavrilovic J, Moens G, Vallés AM, Thiery JP: Amplification of invasiveness in organotypic cultures after NBT-II rat bladder carcinoma stimulation with in vitro scattering factors. Cell Adh Com 11: 297–309, 1991 Google Scholar
Jouanneau J, Moens G, Bourgeois Y, Poupon MF, Thiery JP: A minority of carcinoma cells producing acidic fibroblast growth factor induces a community effect for tumor progression. Proc Natl Acad Sci USA 91: 286–290, 1994 Google Scholar
Gurdon JB, Lemaire P, Kato K: Community effects in related phenomena in development. Cell 75: 831–834, 1993 Google Scholar
Jouanneau J, Plouet J, Moens G, Thiery JP: FGF-2 and FGF-1 expressed in rat bladder carcinoma cells have similar angiogenic potential but different tumorigenic properties in vivo. Oncogene 14: 671–676, 1997 Google Scholar
Bellusci S, Moens G, Thiery JP, Jouanneau J: A scatter factor-like factor is produced by a metastatic variant of a bladder carcinoma line. J Cell Science 107: 1277–1287, 1994 Google Scholar
Aaronson SA: Growth factors and cancer. Science 254: 1146–1152, 1991 Google Scholar
Fan Z, Mendelsohn J: Therapeutic application of antigrowth factor receptor antibodies. Curr Op Oncology 10: 67–73, 1998 Google Scholar
Chodak GW, Hospelhorn V, Judge SM, Mayforth R, Koeppen H, Sasse J: Increased levels of fibroblast growth factor-like activity in urine from patients with bladder or kidney cancer. Cancer Res 48: 2083–2088, 1988 Google Scholar
Chopin DK, Caruelle JP, Colombel M, Palcy S, Ravery V, Caruelle D, Abbou C, Barritault D: Increased immunodetection of acidic fibroblast growth factor in bladder cancer, detectable in urine. J Urol 150: 1126–1130, 1993 Google Scholar
Nguyen M, Watanabe H, Budson AE, Richie JP, Folkman J: Elevated levels of the angiogenic peptide basic fibroblast growth factor in urine of bladder cancer patients. J Natl Cancer Inst 85: 241–242, 1993 Google Scholar
Yan G, Fukabori Y, McBride G, Nikolaropolous S, McKeehan WL: Exon switching and activation of stromal and embryonic fibroblast growth factor (FGF)-FGF receptor genes in prostate epithelial cells accompany stromal independance and malignancy. Mol Cell Biol 13: 4513–4522, 1993 Google Scholar
Yamaguchi F, Saya H, Bruner JM, Morrison RS: Differential expression of two fibroblast growth factor-receptor genes is associated with malignant progression in human astrocytomas. Proc Natl Acad Sci USA 91: 484–488, 1994 Google Scholar
Nakagawara A, Arima-Nakagawara M, Azar CG, Scavarda NJ, Brodeur GM: Clinical significance of expression of neurotrophic factors and their receptors in neuroblastoma. Progress of clinical and biological research 385: 155–161, 1994 Google Scholar
Kim IY, Ahn HJ, Lang S, Oefelein MG, Osyasu R, Kolowski KM, Lee C: Loss of expression of transforming growth factor beta receptors is associated with poor prognosis in prostate cancer patients. Clin Cancer Res 4: 1625–1630, 1998 Google Scholar
Werner S, Weinberg W, Liao X, Peters KG, Blessing M, Yuspa SH, Weiner RL, Williams LT: Targeted expression of a dominant-negative FGF receptor mutant in the epidermis of transgenic mice reveals arole of FGF in keratinocyte organization and differentiation. EMBO J 12: 2635–2643, 1993 Google Scholar
Werner S, Smola H, Liao X, Longaker MT, Krieg T, Hofschneider PH, Williams LT: The function of KGF in morphogenesis of epithelium and reepitheliasation of wounds. Science 266: 819–822, 1994 Google Scholar
Itoh H, Hattori Y, Sakamoto H, Ishii H, Kishi T, Sasaki H, Yoshida T, Koono M, Sugimura T, Terada M: Preferential alternative splicing in cancer generates a K-sam messenger RNA with higher transforming activity. Cancer Res 54: 3237–3241, 1994 Google Scholar
Chesi M et al.: Frequent translocation t(4;14)(p16.3; q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3. Nature Genet 16: 260–264, 1997 Google Scholar
Ornitz DM, Leder P: Ligand specificity and heparin dependence of fibroblast growth factor receptors 1 and 3. J Biol Chem 267: 16305–16311, 1992 Google Scholar
Kanai M, Goke M, Tsunekawa S, Podolsky D: Signal transduction pathway of human fibroblast growth factor receptor 3. Identification of anovel 66-kDaphosphoprotein. J Biol Chem 272: 6621–6628, 1997 Google Scholar
Naski MC, Wang Q, Xu J, Ornitz DM: Graded activation of fibroblast growth factor receptor 3 by mutations causing achondroplasia and thanatophoric dysplasia. Nature Genet 13: 233–237, 1996 Google Scholar
Webster M, D'Avis PY, Robertson SC, Donhogue DJ: Profound ligand-independent kinase activation of fibroblast growth factor receptor 3 by the activation loop mutation responsible for a lethal skeletal dysplasia, thanatophoric dysplasia type II. Mol Cell Biol 16: 4081–4087, 1996a Google Scholar
Webster M, Donhogue DJ: Consitutive activation of fibroblast growth factor receptor 3 by the transmembrane domain mutation found in achondroplasia. EMBO J 15: 520–527, 1996b Google Scholar
Colvin JS, Bohne BA, Harding GW, McEwen DG, Ornitz DM: Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3. Nature Genet 12: 390–397, 1996 Google Scholar
Deng C, Wynshaw-Boris A, Zhou F, Kuo A, Leder P: Fibroblast growth factor receptor 3 is a negative regulator of bone growth. Cell 84: 911–921, 1996 Google Scholar
Ricol D, Cappellen D, El Marjou A, Gil-Diez de Medina S, Girault J-M, Ferry G, Tucker G, Poupon M-F, Chopin D, Thiery JP, Radvanyi F: Tumour suppressive properties of fibroblast growth factor receptor 2-IIIb in human bladder cancer. Oncogene (in press) 1999
Birchmeier W, Behrens J: Cadherin expression in carcinomas: role in the formation of cell junction and the prevention of invasiveness. Biochem Biophys Acta 1198: 11–26, 1994 Google Scholar
Gil-Diez de Medina S, Popov Z, Chopin DK, Southgate J, Tucker G, Delouvée A, Thiery JP, Radvanyi F: Relationship between E-cadherin and Fibroblast Growth Factor Receptor 2b expression in bladder carcinomas. Oncogene (in press) 1999
Schmidt L et al.: Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas. Nature Genet 16: 68–73, 1997 Google Scholar
Kolibaba KS, Druker BJ: Protein tyrosine kinases and cancer. Biochimica et Biophysica Acta 1333: 217–248, 1997 Google Scholar
Ravery V, Colombel M, Popov Z, Bastuji S, Patard JJ, Bellot J, Abbou CC, Fradet Y, Chopin DK: Prognostic value of epidermal growth factor-receptor, T138 and T43 expression in bladder cancer. Br J Cancer 71: 196–200, 1995 Google Scholar
Kobrin MS, Yamanaka Y, Friess H, Lopez ME, Korc M: Aberrant expression of type I fibroblast growth factor receptor in human pancreatic adenocarcinomas. Cancer Res 53: 4741–4744, 1993 Google Scholar
Jacquemier J, Adelaide J, Parc P, Penault-Llorca F, Planche J, DeLapeyriere O, Birnbaum D: Expression of the FGFR1 gene in human breast carcinoma cells. Int J Cancer 59: 373–378, 1994 Google Scholar
Xiao S et al.: FGFR1 is fused with a novel zinc-finger gene, ZNF198, in the t(8;13) leukaemia/lymphoma syndrome. Nature Genet 18: 84–87, 1998 Google Scholar
Feng S, Wang F, Matsubara A, Kan M, McKeehan WL: Fibroblast growth factor receptor 2 limits and receptor 1 accelerates tumorigenicity of prostate epithelial cells. Cancer Res 57: 5369–5378, 1997 Google Scholar
El Marjou A, Delouvee A, Thiery JP, Radvanyi F: A positive autocrine loop EGF-R/ligands is involved in chemically-inducedmousebladder tumourprogression. Submitted 1999
Boyer B, Thiery JP: Epithelium-mesenchyme interconversion as example of epithelial plasticity. Apmis 101: 257–268, 1993 Google Scholar