Molecular Analysis of the PTEN, TP53 and CDKN2A Tumor Suppressor Genes in Long-term Survivors of Glioblastoma Multiforme (original) (raw)
References
Lantos PL, VandenBerg SR, Kleihues P: Tumours of the nervous system. In: Graham DI, Lantos PL (eds) Greenfield's Neuropathology. 6th edn. Arnold, 1997, pp 600-626
Imperato JP, Paleologos NA, Vick NA: Effects of treatment on long-term survivors with malignant astrocytomas. Ann Neurol 28: 818-822, 1990 Google Scholar
Forsyth PA, Cairncross JG: Treatment of malignant glioma in adults. Curr Opin Neurol 8: 414-418, 1995 Google Scholar
Salford L, Brun A, Nirfalk S: Ten-year survival among patients with supratentorial astrocytomas grade III and IV. J Neurosurg 69: 506-509, 1988 Google Scholar
Chandler KL, Prados MD, Malec M, Wilson CB: Long-term survival in patients with glioblastoma multiforme. Neurosurgery 32: 716-720, 1993 Google Scholar
Morita M, Rosenblum MK, Bilsky MH, Fraser RAR, Rosenfeld MR: Long-term survivors of glioblastoma multiforme: clinical and molecular characteristics. J Neuro-Oncol 27: 259-266, 1996 Google Scholar
Scott JN, Rewcastle NB, Brasher PM, Fulton D, Hagen NA, MacKinnon JA, Sutherland G, Cairncross JG, Forsyth P: Long-term glioblastoma multiforme survivors: a population-based study. Can J Neurol Sci 25: 197-201, 1998 Google Scholar
Curran Jr WJ, Scott CB, Horton J, Nelson JS, Weinstein AS, Fischbach AJ, Chang CH, Rotman M, Asbell SO, Krisch RE, Nelson DF: Recursive partitioning analysis of prognostic factors in three radiation therapy oncology group malignant glioma trials. J Natl Cancer Inst 85: 704-710, 1993 Google Scholar
Devaux BC, O'Fallon JR, Kelly PJ: Resection, biopsy, and survival in malignant glial neoplasms. A retrospective study of clinical parameters, therapy, and outcome. J Neurosurg 78: 767-775, 1993 Google Scholar
Collins VP: Progression as exemplified by human astrocytic tumors. Semin Cancer Biol 9: 267-276, 1999 Google Scholar
Levine AJ: p53, the cellular gatekeeper for growth and division. Cell 88: 323-331, 1997 Google Scholar
Freedman DA, Wu L, Levine AJ: Functions of the MDM2 oncoprotein. Cell Mol Life Sci 55: 96-107, 1999 Google Scholar
Reifenberger G, Liu L, Ichimura K, Schmidt EE, Collins VP: Amplification and overexpression of the MDM2 gene in a subset of human malignant gliomas without p53 mutations. Cancer Res 53: 2736-2739, 1993 Google Scholar
Duerr E-M, Rollbrocker B, Hayashi Y, Peters N, Meyer-Puttlitz B, Louis DN, Schramm J, Wiestler OD, Parsons R, Eng C, von Deimling A: PTEN mutations in gliomas and glioneuronal tumors. Oncogene 16: 2259-2264, 1998 Google Scholar
Lin H, Bondy ML, Langford LA, Hess KR, Delclos GL, Wu X, Chan W, Pershouse MA, Yung WKA, Steck PA: Allelic deletion analyses of MMAC/PTEN and DMBT1 loci in gliomas: relationship to prognostic significance. Clin Cancer Res 4: 2447-2454, 1998 Google Scholar
Ono Y, Tamiya T, Ichikawa T, Kunishio K, Matsumoto K, Furuta T, Ohmoto T, Ueki K, Louis DN: Malignant astrocytomas with homozygousCDKN2gene deletions have higher Ki-67 proliferation indices. J Neuropathol Exp Neurol 55: 1026-1031, 1996 Google Scholar
Hayashi Y, Ueki K, Waha A, Wiestler OD, Louis DN, von Deimling A: Association of EGFR gene amplification and CDKN2 (p16/MTS1) gene deletion in glioblastoma multiforme. Brain Pathol 7: 871-875, 1997 Google Scholar
Kleihues P, Burger PC, Scheithauer BW: Histological typing of tumors of the central nervous system. In: Kleihues P, Burger PC, Scheithauer BW (eds) International Histological Classification of Tumors. World Health Organization, Geneva, 1993 Google Scholar
Kraus JA, Bolln C, Wolf HK, Neumann J, Kindermann D, Fimmers R, Forster F, Baumann A, Schlegel U: TP53 alterations and clinical outcome in low grade astrocytomas. Genes Chromosomes Cancer 10: 143-149, 1994 Google Scholar
Kraus JA, Koopmann J, Kaskel P, Maintz D, Brandner S, Schramm J, Louis DN, Wiestler OD, von Deimling A: Shared allelic losses on chromosomes 1p and 19q suggest a common origin of oligodendroglioma and oligoastrocytoma. J Neuropathol Exp Neurol 54: 91-95, 1995 Google Scholar
Riemenschneider MJ, Büschges R, Wolter M, Reifenberger J, Boström J, Kraus JA, Schlegel U, Reifenberger G: Amplification and overexpression of the MDM4 (MDMX) gene from 1q32 in a subset of malignant gliomas without TP53 mutation or MDM2 amplification. Cancer Res 59: 6091-6096, 1999 Google Scholar
Waha A, Baumann A, Wolf HK, Fimmers R, Neumann J, Kindermann D, Astrahantseff K, Blümcke I, von Deimling A, Schlegel U: Lack of prognostic relevance of alterations in the epidermal growth factor receptor-transforming growth factor-alpha pathway in human astrocytic gliomas. J Neurosurg 85: 634-641, 1996 Google Scholar
DeAngelis LM, Burger PC, Green SB, Cairncross JG: Malignant glioma: who benefit from adjuvant chemotherapy? Ann Neurol 44: 691-695, 1998 Google Scholar
Vertosick FT, Selker RG: Long-term survival after the diagnosis of malignant glioma: a series of 22 patients surviving more than 4 years after diagnosis. Surg Neurol 38: 359-363, 1992 Google Scholar
Salcman M, Scholtz H, Kaplan RS, Kulik S: Long-term survival in patients with malignant astrocytoma. Neurosurgery 34: 213-220, 1994 Google Scholar
Olivera C, Bartley M, Ferrall S, Phuphanich S: Long-term malignant glioma survivors over ten years: prognostic factors. Proceedings of ASCO16: 407a, 1997 (Abstr)
Chang CH, Horton J, Schoenfeld D, Salazer O, Perez-Tamayo R, Kramer S, Weinstein A, Nelson JS, Tsukada Y: Comparison of postoperative radiotherapy and combined postoperative radiotherapy and chemotherapy in the multidisciplinary management of malignant gliomas. A joint Radiation Therapy Oncology Group and Eastern Cooperation Oncology Group study. Cancer 52: 997-1007, 1983 Google Scholar
Coffey RJ, Lunsford LD, Taylor FH: Survival after stereotactic biopsy of malignant gliomas. Neurosurgery 22: 465-473, 1988 Google Scholar
Shapiro WR, Green SB, Burger PC, Mahaley MS, Selker RG, van Gilder JC, Robertson JT, Ransohoff J, Mealey J, Strike TA, Pistenmaa DA: Randomized trial of three chemotherapy regimens and two radiotherapy regimens in postoperative treatment of malignant glioma. J Neurosurg 71: 1-9, 1989 Google Scholar
Albert FK, Forsting M, Sartor K, Adams HP, Kunze S: Early postoperative magnetic resonance imaging after resection of malignant glioma: objective evaluation of residual tumor and its influence on regrowth and prognosis. Neurosurgery 34: 45-60, 1994 Google Scholar
Weber RG, Sommer C, Albert FK, Kiessling M, Cremer T: Clinically distinct subgroups of glioblastoma multiforme studied by comparative genomic hybridization. Lab Invest 74: 108-119, 1996 Google Scholar
Galanis E, Buckner J, Kimmel D, Jenkins R, Alderete B, O'Fallon J, Wang CH, Scheithauer BW, James CD: Gene amplification as a prognostic factor in primary and secondary high-grade malignant gliomas. Int J Oncol 13: 717-724, 1998 Google Scholar
James CD, Galanis E, Frederick L, Kimmel DW, Cunningham JM, Atherton-Skaff PJ, O'Fallon JR, Jenkins RB, Buckner JC, Hunter SB, Olson JJ, Scheithauer BW: Tumor suppressor gene alterations in malignant gliomas: histopathological associations and prognostic evaluation. Int J Oncol 15: 547-553, 1999 Google Scholar
Rasheed BKA, Stenzel TT, McLendon RE, Parsons R, Friedman AH, Friedman HS, Bigner DD, Bigner SH: PTEN gene mutations are seen in high-grade but not in low-grade gliomas. Cancer Res 57: 4187-4190, 1997 Google Scholar
Wang SI, Puc J, Li J, Bruce JN, Cairns P, Sidransky D, Parsons R: Somatic mutations ofPTEN in glioblastoma multiforme Cancer Res 57: 4183-4186, 1997 Google Scholar
Boström J, Cobbers JMJL, Wolter M, Tabatabai G, Weber RG, Lichter P, Collins VP, Reifenberger G: Mutation of the PTEN (MMAC1) tumor suppressor gene in a subset of glioblastomas but not in meningiomas with loss of chromosome arm 10q. Cancer Res 58: 29-33, 1998 Google Scholar
Schmidt EE, Ichimura K, Goike HM, Moshref A, Liu L, Collins VP: Mutational profile of the PTEN gene in primary human astrocytic tumors and cultivated xenografts. J Neuropathol Exp Neurol 58: 1170-1183, 1999 Google Scholar
Pardo FS, Hsu DW, Hedley-Whyte ET, Efird J, Schmidt EV: High p53 expression is prognostic of overall survival in adult supratentorial astrocytoma patients. J Neuro-Oncol 15 (Suppl): S19, 1993 Google Scholar
Louis DN: The p53 gene and protein in human brain tumors. J Neuropathol Exp Neurol 53: 11-21, 1994 Google Scholar
Rasheed BKA, McLendon RE, Herndon JE, Friedman HS, Friedman AH, Bigner DD, Bigner SH: Alterations of the TP53 gene in human gliomas. Cancer Res 54: 1324-1330, 1994 Google Scholar
Leenstra S, Oskam NT, Bijleveld EH, Bosch DA, Troost D, Hulsebos TJ: Genetic sub-types of human malignant astrocytoma correlate with survival. Int J Cancer 79: 159-165, 1998 Google Scholar
Kleihues P, Ohgaki H: Primary and secondary glioblastomas: from concept to clinical diagnosis. Neuro-Oncology 1: 44-51, 1999 Google Scholar
Schmidt EE, Ichimura K, Reifenberger G, Collins VP: CDKN2 (p16/MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas. Cancer Res 54: 6321-6324, 1995 Google Scholar
Ueki K, Onon Y, Henson JW, von Deimling A, Louis DN: CDKN2 or RB alterations occur in the majority of glioblastomas and are inversely related. Cancer Res 56: 150-153, 1996 Google Scholar