Prevalence of Barrett's Esophagus in Hispanics Is Similar to Caucasians (original) (raw)

Abstract

Barrett's esophagus (BE) is considered to be adisease of white males with a prevalence ranging from0.5 to 4.0% in patients undergoing upper endoscopy (EGD)for any indication, and from 12 to 15% in patients with gastroesophageal reflux disease (GERD).The prevalence of BE in Hispanics is not known, but itis assumed to be lower. The aims of this study were todetermine the prevalence of BE in Hispanic patients and to compare demographic and endoscopiccharacteristics with Caucasian patients with BE. Recordsof patients undergoing an EGD between October 1993 andOctober 1996 were retrospectively reviewed. Patients were included in the study only if they hadcolumnar-appearing esophageal mucosa at endoscopy andintestinal metaplasia with Alcian blue-staining gobletcells on biopsy. An extensive chart review was performed in patients with BE. There were 75 new cases ofBE discovered: 60 (80%) were Caucasians, 6 (8%)Hispanics, 1 (1.4%) Native American, and 8 (10.6%)patients with either unknown or unconfirmed ethnicity. Of the 75 patients, 74 male, and the mean agewas 65 ± 11.4 years (range 36-92 years). Theprevalence of BE in Caucasians and Hispanics undergoingEGD for any reason was similar (5.3% and 3.8%,respectively, P = 0.563). The prevalence of BE in patientspresenting with GERD symptoms was also similar betweenCaucasians and Hispanics (25% and 16%, respectively, P= 0.304). The two groups did not differ significantly with respect to age, symptoms, habits, orendoscopic findings. In conclusion, the prevalence of BEamong Hispanic patients is similar to Caucasianpatients, an unexpected finding.

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REFERENCES

  1. Goldman MC, Beckman RC: Barrett syndrome: Case report with discussion about concepts of pathogenesis. Gastroenterology 39:104-111, 1960
    Google Scholar
  2. Mossberg SM: The columnar-lined esophagus (Barrett syndrome) - an acquired condition? Gastroenterology 50:671- 676, 1966
    Google Scholar
  3. Naef AP, Savary M, Ozzello L: Columnar-lined lower esophagus: An acquired lesion with malignant predisposition. J Thorac Cardiovasc Surg 70:825- 835, 1975
    Google Scholar
  4. Gillen P, Keeling P, Byrne PJ, Hennessy TPJ: Barrett's oesophagus: pH profile. Br J Surg 74:774 - 776, 1987
    Google Scholar
  5. Iascone C, De Meester TR, Little AG, Skinner DB: Barrett's esophagus: Functional assessment, proposed pathogenesis, and surgical therapy. Arch Surg 118:543- 549, 1983
    Google Scholar
  6. Kim R, Weissfeld JL, Reynolds JC, Kuller LH: Etiology of Barre tt's metaplasia and esophageal adenocarcinoma. Cancer Epidemiol, Biomarkers Prev 6:369 - 377, 1997
    Google Scholar
  7. Cameron AJ, Zinsmeister AR, Ballard DJ, Carney JA: Prevalence of columnar-lined (Barrett's) esophagus: Comparison of population-based clinical and autopsy findings. Gastroenterology 99:918 - 922, 1990
    Google Scholar
  8. Cameron AJ, Lomboy CT: Barrett's esophagus: Age, prevalence, and extent of columnar epithelium. Gastroenterology 103:1241- 1245, 1992
    Google Scholar
  9. Gruppo Operativo per lo Studio delle Percancerosi dell 'Esofago (GOSPE). Barrett's esophagus: Epidemiological and clinical results of a multicentric survey. Int J Cancer 48:364 - 368, 1991
    Google Scholar
  10. Spechler ST, Goyal RK: Medical progress: Barrett's esophagus. N Engl J Med 315:362- 371, 1985
    Google Scholar
  11. Sarr MG, Hamilton SR, Marrone GC, Cameron JL: Barrett's esophagus: Its prevalence and association with adenocarcinoma in patients with symptoms of gastroesophage al reflux. Am J Surg 149:187- 193, 1985
    Google Scholar
  12. Winters C Jr, Spurling TJ, Chobanian SJ, Curtis DJ, Esposito RL, Hacker JF, Johnson DA, Cruess DF, Cotelingham JD, Gurney MS, Cattau EL: Barre tt's esophagus: A prevalent, occult complication of gastroe sophageal reflux disease. Gastroente rology92:118 - 124, 1987
    Google Scholar
  13. Skinner DB, Walther BC, Riddell RH, Schmidt H, Iascone C, De Meesster TR: Barrett's esophagus: Comparison of benign and malignant cases. Ann Surg 198:554 - 565, 1983
    Google Scholar
  14. Stein HJ, Siewert JR: Barrett's esophagus: Pathogenesis, epidemiology, functional abnormalities, malignant degeneration, and surgical management. Dysphagia 8:276 - 288, 1993
    Google Scholar
  15. Smith RRL, Boitnott JK, Hamilton SR, Rogers EL: The spectrum of carcinoma arising in Barrett's esophagus: A clinicopathologic study of 26 patients. Am J Surg Pathol 8:563- 573, 1984
    Google Scholar
  16. Yeh C, Hsu CT, Ho AS, Sampliner RE, Fass R: Erosive esophagitis and Barrett's esophagus in Taiwan: A higher frequency than expected. Dig Dis Sci42:702- 706, 1997
    Google Scholar
  17. Sharma P, Morales TG, Bhattacharyya A, Garewal HS, Sampliner RE: Dysplasia in short segment Barrett's esophagus- a prospective 3 year follow-up. Am J Gastroenterol 92:2012–2016, 1997
    Google Scholar

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Authors

  1. Korina Bersentes
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  2. Ronnie Fass
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  3. Sukhdeep Padda
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  4. Cynthia Johnson
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  5. Richard E. Sampliner
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Bersentes, K., Fass, R., Padda, S. et al. Prevalence of Barrett's Esophagus in Hispanics Is Similar to Caucasians.Dig Dis Sci 43, 1038–1041 (1998). https://doi.org/10.1023/A:1018834902694

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