CASE REPORT: Fatal Progressive Hepatic Necrosis Associated with Lamotrigine Treatment: A Case Report and Literature Review (original) (raw)

• 226 Accesses
• 59 Citations
• Explore all metrics

Access this article

Log in via an institution

Subscribe and save

• Starting from 10 chapters or articles per month
• Access and download chapters and articles from more than 300k books and 2,500 journals
• Cancel anytime View plans

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

REFERENCES

1. Brodie MJ: Lamotrigine. The Lancet 339:1397–1400, 1992
   Google Scholar
2. Messenheimer: Lamotrigine in children. Drug Safety 22:303–312, 2000
   Google Scholar
3. Schaub N, Bircher AJ: Severe Hypersensitivity syndrome to lamotrigine confirmed by lymphocyte stimulation in vitro. Allergy 55:191–193, 2000
   Google Scholar
4. Schaub J, Williamson P, Barnes E, Trewby P: Multisystem adverse reaction to lamotrigine. The Lancet 344:481, 1994
   Google Scholar
5. Makin AJ, Fitt S, Williams R, Duncan JS: Fulminant hepatic failure induced by lamotrigine. BMJ 311:292, 1995
   Google Scholar
6. Fayad M, Choueiri R, Mikati M: Potential hepatotoxicity of lamotrigine. Pediatr Neurol 22:49–52, 2000
   Google Scholar
7. Arnon R, DeVivo D, Defelice AR, Kazlow PG: Acute hepatic failure in a child treated with lamotrigine. Pediatr Neurol 18:251–252, 1998
   Google Scholar
8. Yuen AWC, Bihari DJ: Multiorgan failure and disseminated intravascular coagulation in severe convulsive seizures. The Lancet 340:618, 1992
   Google Scholar

Download references

Author information

Authors and Affiliations

1. Department of Pathology, University of California San Diego, La Jolla, California, USA
   Kerith Overstreet, Cynthia Behling & Eliezer Masliah
2. Department of Medicine, Gastroenterology/Hepatology Division, University of California, San Diego Medical Center, San Diego, California, USA
   Christopher Costanza & Tarrek Hassanin

Authors

1. Kerith Overstreet
2. Christopher Costanza
3. Cynthia Behling
4. Tarrek Hassanin
5. Eliezer Masliah

Rights and permissions

About this article

Cite this article

Overstreet, K., Costanza, C., Behling, C. et al. CASE REPORT: Fatal Progressive Hepatic Necrosis Associated with Lamotrigine Treatment: A Case Report and Literature Review.Dig Dis Sci 47, 1921–1925 (2002). https://doi.org/10.1023/A:1019627618972

Download citation

• Issue date: September 2002
• DOI: https://doi.org/10.1023/A:1019627618972