The 3D structure of human chromosomes in cell nuclei (original) (raw)
Bártová E, Kozubek S, Jirsová P et al. (2001) Higher-order chromatin structure of human granulocytes. Chromosoma110: 360-370. PubMed Google Scholar
Bártová E, Kozubek S, Jirsová P et al. (2002) Nuclear structure and gene activity in human differentiated cells. J Struct Biol (in press).
Belmont AS, Bruce K (1994) Visualization of G1 chromosomes, A folded, twisted, supercoiled chromonema model of interphase chromatide structure. J Cell Biol127: 287-302. ArticlePubMedCAS Google Scholar
Belmont AS, Dietzel S, Nye AC, Strukov YG, Tumbar T (1999) Large scale chromatin structure and function. Curr Opin Cell Biol11: 307-311. ArticlePubMedCAS Google Scholar
Boyle S, Gilchrist S, Bridger JM, Mahy NL, Ellis JA, Bickmore WA (2001) The spatial organization of human chromosomes within the nuclei of normal and emerin-mutant cells. Hum Mol Genet10: 211-219. ArticlePubMedCAS Google Scholar
Brown KE, Guest SS, Smale ST, Hahm K, Merkenschlager M, Fisher AG(1997) Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin. Cell91: 845-854. ArticlePubMedCAS Google Scholar
Brown KE, Baxter J, Graf D, Merkenschlager M, Fisher AG (1999) Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division. Mol Cell3: 207-217. ArticlePubMedCAS Google Scholar
Caron H, Van Schaik B, Van der Mee M et al. (2001) The human transcriptom map, Clustering of highly expressed genes in chromosomal domains. Science291: 1289-1292. ArticlePubMedCAS Google Scholar
Carvalho C, Pereira HM, Ferreira J et al. (2001) Chromosomal G-dark bands determine the spatial organization of centromeric heterochromatin in the nucleus. Mol Biol Cell12: 3563-3572. PubMedCAS Google Scholar
Chevret E, Volpi EV, Sheer D (2000) Mini review: Form and function in the human interphase chromosome. Cytogenet Cell Genet90: 13-21. ArticlePubMedCAS Google Scholar
Cockel M, Gasser, S (1999) Nuclear compartments and gene regulation. Curr Opin Genet Dev9: 199-205. Article Google Scholar
Cremer T, Cremer C (2001) Chromosome territories nuclear architecture and gene regulation in mammalian cells. Nature Rev Genet2: 292-301. ArticleCAS Google Scholar
Cremer T, Lichter P, Borden J, Ward DC, Manuelidis L (1988) Detection of chromosome aberrations in metaphase and interphase tumor cells by in situ hybridization using chromosome specific library probes. Hum Genet80: 235-246. ArticlePubMedCAS Google Scholar
Cremer T, Kreth G, Koester H et al. (2000) Chromosome territories, interchromatin domain compartment and nuclear matrix. An integrated view of the functional nuclear architecture. Crit Rev Eucar Gene Expres10: 179-212. CAS Google Scholar
Croft JA, Bridger JM, Boyle S, Perry P, Teague P, Bickmore WA (1999) Differences in the localization and morphology of chromosomes in the human nucleus. J Cell Biol145: 1119-1131. ArticlePubMedCAS Google Scholar
Ferguson M, Ward DC (1992) Cell cycle dependent chromosomal movement in premitotic human T-lymphocyte nuclei. Chromosoma101: 557-565. ArticlePubMedCAS Google Scholar
Ferreira J, Paolella G, Ramos C, Lamond AL (1997) Spatial organization of large-scale chromatin domains in the nucleus A magnified view of single chromosome territories. J Cell Biol139: 1597-1610. ArticlePubMedCAS Google Scholar
Koutná I, Kozubek S, Žaloudík J et al. (2000) Topography of genetic loci in tissue samples: towards new diagnostic tool using interphase FISH and high-resolution image analysis techniques. Anal Cell Pathol20: 173-185. Google Scholar
Kozubek M, Kozubek S, Lukášová E et al. (1999) High-resolution cytometry of FISH dots in interphase cell nuclei. Cytometry36: 279-293. Google Scholar
Kozubek M, Kozubek S, Lukášová E et al. (2001) Combined confocal and wide-field high-resolution cytometry of FISH stained cells. Cytometry45: 1-12. Google Scholar
Kozubek S, Lukášová E, Rýznar L et al. (1997) Distribution of ABL and BCR genes in cell nuclei of normal and irradiated lymphocytes. Blood89: 4537-4545. Google Scholar
Kozubek S, Lukášová E, Marečková A et al. (1999) The topological organization of chromosomes 9 and 22 in cell nuclei has a determinative role in the induction of t(9,22) translocations and in the pathogenesis of t(9,22) leukemias. Chromosoma108: 426-435. Google Scholar
Kozubek S, Lukášová E, Jirsová P et al. (2002) 3D structure of the human genome: Order in randomness. Chromosoma (in press).
Kurz A, Lampel S, Nickolenko JE et al. (1996) Active and inactive genes localize preferentially in the periphery of chromosome territories. J Cell Biol135: 1195-1205. ArticlePubMedCAS Google Scholar
Lichter P, Cremer T, Borden J, Manuelidis L, Ward DC (1988) Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries. Hum Genet80: 224-234. ArticlePubMedCAS Google Scholar
Nagele R, Freeman T, McMorrow L, Lee H (1995) Precise spatial positioning of chromosomes during metaphase: evidence for chromosomal order. Science270: 1831-1835. PubMedCAS Google Scholar
Nagele RG, Valesco AQ, Anderson WJ et al. (2000) Telomere associations in interphase nuclei: possible role inmaintenance of interphase chromosome topology. J Cell Sci114: 377-388. Google Scholar
Neves H, Ramos C, Gomez da Silva M, Parreira A, Parreira L (1999) The nuclear topography of ABL, BCR, PML and RARa genes: Evidence for gene proximity in specific phases of the cell cycle and stages of hematopoietic differentiation. Blood93: 1197-1207. PubMedCAS Google Scholar
Nikiforova MN, Stringer JR, Blough R, Medvedovic M, Fagin JA, Nikiforov YE (2000) Proximity of chromosomal loci that participate in radiation-induced rearrangements in human cells. Science290: 138-142. ArticlePubMedCAS Google Scholar
Nogami M, Nogami O, Kagotani K et al. (2000) Intranuclear arrangement of human chromosome 12 correlates to largescale replication domains. Chromosoma108: 514-522. ArticlePubMedCAS Google Scholar
Pinkel D, Landegent J, Collins C et al. (1988) Fluorescence in situ hybridization with human chromosome-specific libraries: detection of trisomy 21 and translocations of chromosomes 4. Proc Natl Acad Sci USA85: 9138-9142. ArticlePubMedCAS Google Scholar
Sachs RK, van den Engh G, Trask B, Yokota H, Hearst JE (1995) A random-walk/giant-loop model for interphase chromosomes. Proc Natl Acad Sci USA92: 2710-2714. ArticlePubMedCAS Google Scholar
Sadoni N, Langer S, Fauth C et al. (1999) Nuclear organization of mammalian genomes: polar chromosome territories build up functionally distinct higher order compartments. J Cell Biol146: 1211-1226. ArticlePubMedCAS Google Scholar
Sadoni N, Sullivan KF, Weinzierl P, Stelzer EHK, Zink D (2001) Large-scale chromatin fibres of living cells display a discontinuous functional organization. Chromosoma110: 39-51. PubMedCAS Google Scholar
Skalníková M, Kozubek S, Lukášová E et al. (2000) Spatial arrangement of genes, centromeres and chromosomes in human blood cell nuclei and its changes during the cell cycle, differentiation and after irradiation. Chromosome Res8: 487-499. Google Scholar
Trask BJ, Massa H, Kenwrick S, Gitschier J (1991)Mapping of human chromosome Xq28 by two-color fluorescence situ hybridization of DNA sequences to interphase cell nuclei. Am J Hum Genet48: 1-15. PubMedCAS Google Scholar
Verschure PJ, van der Kraan I, Manders EMM, van Driel R (1999) Spatial relationship between transcription sites and chromosome domains. J Cell Biol147: 13-24. ArticlePubMedCAS Google Scholar
Volpi EV, Chevret E, Jones T et al. (2000) Large-scale chromatin organization of the major histocompatibility complex and other regions of human chromosome 6 and its response to interferon in interphase nuclei. J Cell Sci113: 1565-1576. PubMedCAS Google Scholar
Yokota, H, van den Engh G, Hearst JE, Sachs RK, Trask BJ (1995) Evidence for the organization of chromatin in megabase pair-sized loops arranged along a random walk path in human G0/G1 interphase nucleus. J Cell Biol130: 1239-1249. ArticlePubMedCAS Google Scholar
Zink D, Cremer T, Saffrich R et al. (1998) Structure and dynamics of human interphase chromosome territories in vivo. Hum Genet102: 241-251. ArticlePubMedCAS Google Scholar