Angiogenesis Sustains Tumor Dormancy in Patients with Breast Cancer Treated with Adjuvant Chemotherapy (original) (raw)

References

  1. Demicheli R, Abbattista A, Miceli R, Valagussa P, Bonadonna G: Time distribution of the reccurrence risk for breast cancer patients undergoing mastectomy: further support about the concept of tumor dormancy. Breast Cancer Res Treat 41: 177-185, 1996
    Google Scholar
  2. Saphner T, Tormey DC, Gray R: Annual hazard rates of recurrence for breast cancer after primary therapy. J Clin Oncol 14: 2738-2746, 1996
    Google Scholar
  3. Karrison TG, Ferguson DJ, and Meier P: Dormancy of mammary carcinoma after mastectomy. J Natl Cancer Inst 91: 80-85, 1999
    Google Scholar
  4. Uhr JW, Scheuermann RH, Street NE, Vitetta ES: Cancer dormancy: opportunities for new therapeutic approaches. Nature Med 3: 505-509, 1997
    Google Scholar
  5. O'Reilly MS, Holmgren L, Shing Y, Chen C, Rosenthal RA, Moses M, Lane WS, Cao Y, Sage EH, Folkman J: Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 79: 315-328, 1994
    Google Scholar
  6. Holmgren L, O'Reilly MS, Folkman J: Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression. Nature Med 1: 149-153, 1995
    Google Scholar
  7. O'Reilly MS, Holmgren L, Chen C, Folkman J: Angiostat in induces and sustains dormancy of human primary tumors in mice. Nature Med 2: 689-692, 1996
    Google Scholar
  8. Greenberg PD: Adoptive T cell therapy of tumors: Mechanisms operative in the recognition and elimination of tumor cells. Adv Immunol 49: 281-355, 1991
    Google Scholar
  9. Wheelock EF, Weinhold KJ, Levich J: The tumor dormant state. Adv Cancer Res 34: 107-140, 1981
    Google Scholar
  10. Marches R, Racila E, Tucker TF, Picker L, Mongini P, Vitetta ES, Scheuermann RH: Tumor dormancy and cell signaling-III: Role of hypercrosslinking of IgM and CD40 on the induction of cell cycle arrest and apoptosis in B lymphoma cells. Ther Immunol 2: 125-136, 1995
    Google Scholar
  11. Albelda SM: Role of integrins and other cell adhesion molecules in tumor progression and metastasis. Lab Invest 68: 4-17, 1993
    Google Scholar
  12. Rounov-Jessen L, Peterson OW, Bissell MJ: Cellular changes involved in conversion of normal to malignant breast: Importance of the stromal reaction. Physiol Rev 76: 69-125, 1996
    Google Scholar
  13. Weidner N, Semple JP, Welch WR, Folkman J: Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma. N Engl J Med 324: 1-8, 1991
    Google Scholar
  14. Gasparini G, Weidner N, Bevilacqua P, Maluta S, Dalla Palma P, Caffo O, Barbareschi M, Boracchi P, Marubini E, Pozza F: Tumor microvessel density, p53 expression, tumor size and peritumoral lymphatic vessel invasion are relevant prognostic markers in node-negative breast carcinoma. J Clin Oncol 12: 454-466, 1994
    Google Scholar
  15. Efron B: Logistic regression, survival analysis, and the Kaplan-Meier curve. J Am Stat Assoc 83: 414-425, 1988
    Google Scholar
  16. Akaike H: Information theory and an extension of the maximum likelihood principle. In: Patrov BN Csaki F (eds) Proceedings of the 2nd International Symposium on Information Theory. Akademia Kiado, Budapest, 1973, pp 267-281.
  17. Gasparini, G: Clinical significance of determination of surrogate markers of angiogenesis in breast cancer. Crit Rev Oncol/Hematol 33: in press 2000
  18. Gasparini G, Barbareschi M, Boracchi P, Verderio P, Caffo O, Meli S, Dalla Palma P, Marubini E, Bevilacqua P: Tumor angiogenesis predicts clinical outcome of nodepositive breast cancer patients treated with adjuvant hormone therapy or chemotherapy. Cancer J Sci Am 1: 131-141, 1995
    Google Scholar
  19. Gasparini G, Toi M, Miceli R, Vermeulen PB, Dittadi R, Biganzoli E, Morabito A, Fanelli M, Gatti C, Suzuki H, Tominaga T, Dirix LY, Gion M: Clinical relevance of vascular endothelial growth factor (VEGF) and thymidine phosphorylase (TP) in patients with node-positive breast cancer treated either with adjuvant chemotherapy or hormonetherapy. Cancer J Sci Am 5: 101-111, 1999
    Google Scholar
  20. Toi M, Kondo S, Suzuki H, Yamamoto Y, Inada K, Imazawa T, Taniguchi T, Tominaga T: Quantitative analysis of vascular endothelial growth factor in primary breast cancer. Cancer 77: 1101-1106, 1996
    Google Scholar
  21. Folkman J: Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1: 27-31, 1995
    Google Scholar
  22. Hamada J, Cavanaugh PG, Lotan A, Nicolson GL: Separable growth and migration factors from large-cell lymphoma cells secreted by microvascular endothelial cells derived from target organs for metastasis. Br J Cancer 66: 349-354, 1992
    Google Scholar
  23. Fidler IJ, Rodinsky R: Search for genes that suppress cancer metastasis. J Natl Cancer Inst 83: 1700-1703, 1996
    Google Scholar
  24. Gasparini G: The rationale and future potential of angiogenesis inhibitors in neoplasia. Drugs 58: 17-38, 1999
    Google Scholar
  25. Gasparini G, Gion M: Molecular-targeted anticancer treatments to biological targets. Challanges related to studydesign and choice of proper end-points. Cancer J 6: 117-131, 2000
    Google Scholar

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