Possibility of Incomplete Sex Linkage in Mammals (original) (raw)

• Letter
• Published: 17 March 1934

Nature volume 133, page 417 (1934)Cite this article

• 733 Accesses
• 14 Citations
• Metrics details

Abstract

IN a paper shortly to be published, Roller and Darlington find that, in the first meiotic division of Rattus norvegicus males, one or two chiasmata are formed between the X and _Y_-chromosomes. If chiasma formation corresponds with the crossing-over of genes, it follows that where the chiasma lies between the locus of a gene and the region in which X and _Y_-chromosomes differ, such a gene will exhibit crossing-over with sex. On the basis of the cytological observations, genes in a certain region of the chromosome should show about 5 per cent crossing-over with sex, in another about 45 per cent. These latter genes would behave in very nearly the same manner as autosomal genes. It thus follows that some genes regarded as autosomal may in reality be incompletely sex-linked. Such linkage would show up in a pedigree of the following type:

Similar content being viewed by others

Article PDF

Author information

Authors and Affiliations

1. John Innes Horticultural Institution, London, S.W.19
   C. D. DARLINGTON, J. B. S. HALDANE & P. CH. ROLLER

Authors

1. C. D. DARLINGTON
   You can also search for this author inPubMed Google Scholar
2. J. B. S. HALDANE
   You can also search for this author inPubMed Google Scholar
3. P. CH. ROLLER
   You can also search for this author inPubMed Google Scholar

Rights and permissions

About this article

Cite this article

DARLINGTON, C., HALDANE, J. & ROLLER, P. Possibility of Incomplete Sex Linkage in Mammals.Nature 133, 417 (1934). https://doi.org/10.1038/133417b0

Download citation

• Issue Date: 17 March 1934
• DOI: https://doi.org/10.1038/133417b0

This article is cited by