An Enzyme from Bacteria able to Destroy Penicillin (original) (raw)

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• Published: 28 December 1940

Nature volume 146, page 837 (1940)Cite this article

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Abstract

FLEMING1 noted that the growth of B. coli and a number of other bacteria belonging to the colityphoid group was not inhibited by penicillin. This observation has been confirmed. Further work has been done to find the cause of the resistance of these organisms to the action of penicillin.

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References

1. Fleming, A., Brit. J. Exp. Path., 10, 226 (1929).
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2. Booth, V. H., and Green, D. E., Biochem. J., 32, 855 (1938).
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3. Chain, E., Florey, H. W., Gardner, A. D., Heatley, N. G., Jennings, M. A., Orr-Ewing, J., and Sanders, A. G., Lancet, 226 (1940).
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Authors and Affiliations

1. Sir William Dunn School of Pathology, Oxford
   E. P. ABRAHAM & E. CHAIN

Authors

1. E. P. ABRAHAM
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2. E. CHAIN
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ABRAHAM, E., CHAIN, E. An Enzyme from Bacteria able to Destroy Penicillin.Nature 146, 837 (1940). https://doi.org/10.1038/146837a0

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• Issue Date: 28 December 1940
• DOI: https://doi.org/10.1038/146837a0

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