Different Heterogeneities of Mouse Hæmoglobin according to Strains (original) (raw)

Nature volume 182, pages 947–948 (1958)Cite this article

Abstract

TWO different electrophoretic hæmoglobin patterns have been demonstrated by paper electrophoresis in inbred strains of mice, and these have been shown to be under genetic control1,2. By means of moving-boundary electrophoresis, four different peaks have been observed in strains of genetically anæmic mice (ref. 3 and Cook, J. (personal communication) has observed three major peaks and two minor ones by chromatography on ‘Amberlite _X_64’). In studies on two different strains of mice by electrophoresis in gelosis, Van Bekkum, D. W., and Welling, W. (personal communication), have demonstrated in one of them the existence of a single hæmoglobin component, and in the other the existence of several components. This communication describes the different patterns obtained by starch gel electrophoresis of hæmoglobins from six inbred strains of mice.

This is a preview of subscription content, access via your institution

Access options

Subscribe to this journal

Receive 51 print issues and online access

$199.00 per year

only $3.90 per issue

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Additional access options:

Similar content being viewed by others

Powder diffraction

Article 18 November 2021

References

  1. Ranney, H. M., and Gluecksohn-Waelsh, S., Ann. Hum. Genet., 19, 269 (1955).
    Article CAS Google Scholar
  2. Gluecksohn-Waelsh, S., Ranney, M., and Sisken, B. F., J. Clin. Invest., 36, 753 (1957).
    Article Google Scholar
  3. Singer, S. J., and Russel, E. S., Proc. U.S. Nat. Acad. Sci., 40, 6 (1954).
    Article ADS CAS Google Scholar
  4. Drabkin, D. L., Arch. Biochem., 21, 224 (1949).
    CAS Google Scholar
  5. Smithies, O., Biochem. J., 61, 629 (1955).
    Article CAS Google Scholar
  6. Grouchy, J. de, Schapira, G., and Dreyfus, J. C., Rev. Franc. Et. Clin. Biol., 3, 377 (1958).
    Google Scholar

Download references

Author information

Authors and Affiliations

  1. Laboratoire de Biochimie, HÔpital des Enfants Malades,
    J. ROSA, G. SCHAPIRA & J. C. DREYFUS
  2. Clinique de Génétique Médicale, HÔpital des Enfants Malades,
    J. DE GROUCHY
  3. Centre de Recherches de l'Association Claude Bernard, Paris
    G. MATHÉ & J. BERNARD

Authors

  1. J. ROSA
    You can also search for this author inPubMed Google Scholar
  2. G. SCHAPIRA
    You can also search for this author inPubMed Google Scholar
  3. J. C. DREYFUS
    You can also search for this author inPubMed Google Scholar
  4. J. DE GROUCHY
    You can also search for this author inPubMed Google Scholar
  5. G. MATHÉ
    You can also search for this author inPubMed Google Scholar
  6. J. BERNARD
    You can also search for this author inPubMed Google Scholar

Rights and permissions

About this article

Cite this article

ROSA, J., SCHAPIRA, G., DREYFUS, J. et al. Different Heterogeneities of Mouse Hæmoglobin according to Strains.Nature 182, 947–948 (1958). https://doi.org/10.1038/182947a0

Download citation

This article is cited by