The Nuclear Membrane as a Barrier to the Free Diffusion of Proteins (original) (raw)

Nature volume 185, pages 250–251 (1960)Cite this article

Abstract

A RECENT investigation of the osmotic properties of the nucleus in intact frog oocytes has indicated that the nuclear membrane of these cells is not freely permeable to large molecules (mol. wt. 40,000 or greater)1. The present investigation was carried out in order to determine whether or not similar results could be obtained for oocytes of an unrelated species.

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References

  1. Harding, C. V., and Feldherr, C. M., J. Gen. Physiol., 42, 1155 (1959).
    Article CAS Google Scholar
  2. Stern, H., and Mirsky, A. E., J. Gen. Physiol., 37, 177 (1953).
    Article CAS Google Scholar

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Author notes

  1. CARL M. FELDHERR
    Present address: College of Physicians and Surgeons, Columbia University, New York

Authors and Affiliations

  1. Division of Biology, Zoological Laboratory, University of Pennsylvania, Philadelphia
    CARL M. FELDHERR & AILENE B. FELDHERR

Authors

  1. CARL M. FELDHERR
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  2. AILENE B. FELDHERR
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FELDHERR, C., FELDHERR, A. The Nuclear Membrane as a Barrier to the Free Diffusion of Proteins.Nature 185, 250–251 (1960). https://doi.org/10.1038/185250a0

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