Changes in X-ray Sensitivity of HeLa Cells during the Division Cycle (original) (raw)

Nature volume 190, pages 1210–1211 (1961) Cite this article

Abstract

MEASUREMENT by Puck and Marcus of the reproductive survival of randomly dividing cultures of HeLa _S_3 cells after X-irradiation revealed an exponential response to dose following a shoulder1. However, the possibility was not excluded that these populations are in fact heterogeneous, the cells undergoing small, or large but brief, fluctuations in sensitivity during the division cycle. We have examined this possibility by irradiating synchronously growing populations at various times after mitosis.

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References

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Authors and Affiliations

  1. Edward Mallinckrodt Institute of Radiology, School of Medicine, and Committee on Molecular Biology, Washington University, St. Louis 10, Missouri
    TOYOZO TERASIMA & L. J. TOLMACH
  2. Department of Bacteriology, Chiba University School of Medicine, Chiba, Japan
    TOYOZO TERASIMA

Authors

  1. TOYOZO TERASIMA
  2. L. J. TOLMACH

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TERASIMA, T., TOLMACH, L. Changes in X-ray Sensitivity of HeLa Cells during the Division Cycle.Nature 190, 1210–1211 (1961). https://doi.org/10.1038/1901210a0

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