Isolation and Characterization of a Compound from the Urine of Schizophrenics (original) (raw)
- Letter
- Published: 02 June 1962
Nature volume 194, pages 897–898 (1962)Cite this article
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Abstract
THE systematic screening of schizophrenic and normal urine in this laboratory has led to the identification of a biologically active compound in urine of schizophrenics. This compound is of particular interest since it does not have the usual sympathomimetic actions of the closely related catecholamines, but does have a depressant effect on the central nervous system1.
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References
- Epstein, D., Gunn, J. A., and Virden, C. J., J. Physiol., 76, 224 (1932).
Article CAS PubMed PubMed Central Google Scholar - Friedhoff, A. J., and Van Winkle, E. (unpublished results).
- Goldstein, M., Friedhoff, A. J., Simmons, C., and Prochoroff, N. N., Experientia, 15, 7, 254 (1959).
Google Scholar - Senoh, S., Daly, J., Axelrod, J., and Witkop, B., J. Amer. Chem. Soc., 81, 6240 (1959).
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Authors and Affiliations
- Psychopharmacology Research Unit, Department of Psychiatry and Neurology, New York University School of Medicine,
ARNOLD J. FRIEDHOFF & ELNORA VAN WINKLE
Authors
- ARNOLD J. FRIEDHOFF
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FRIEDHOFF, A., WINKLE, E. Isolation and Characterization of a Compound from the Urine of Schizophrenics.Nature 194, 897–898 (1962). https://doi.org/10.1038/194897b0
- Issue Date: 02 June 1962
- DOI: https://doi.org/10.1038/194897b0