Transplantability and Life Span of Mammary Gland during Serial Transplantation in Mice (original) (raw)

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• Published: 14 January 1967

Nature volume 213, pages 193–194 (1967)Cite this article

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Abstract

SMALL segments of mammary tissues obtained from a 358 day old virgin female C_57_BL mouse and from a 734 day old virgin female CBA mouse, when transplanted into genetically compatible mice, regenerated glands which appeared normal and which responded to either exogenous or endogenous hormonal stimulation in a manner similar to that of the mammary glands of the host, and secreted milk when the hosts nursed young1,2. The quiescent status of the mammary glands of old mice was attributed to their environment, particularly the hormonal status of the animal rather than to the ageing of mammary tissues themselves.

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References

1. Hoshino, K., J. Nat. Cancer Inst., 29, 835 (1962).
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2. Hoshino, K., Anat. Rec., 150, 221 (1964).
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3. Hoshino, K., J. Nat. Cancer Inst., 30, 585 (1963).
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Authors and Affiliations

1. Department of Anatomy and Cancer Research Laboratory, University of Western Ontario, London, Ontario, Canada
   KAZUMASA HOSHINO
2. Department of Anatomy, Yale University School of Medicine, New Haven, Connecticut
   WILLIAM U. GARDNER

Authors

1. KAZUMASA HOSHINO
2. WILLIAM U. GARDNER

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HOSHINO, K., GARDNER, W. Transplantability and Life Span of Mammary Gland during Serial Transplantation in Mice.Nature 213, 193–194 (1967). https://doi.org/10.1038/213193a0

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• Issue date: 14 January 1967
• DOI: https://doi.org/10.1038/213193a0

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