Chromosome Marker Studies in the Irradiated Chick Embryo (original) (raw)

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• Published: 02 September 1967

Nature volume 215, pages 1081–1082 (1967)Cite this article

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Abstract

THE repopulation of the irradiated adult animal by injected myeloid cells has provided a considerable amount of qualitative and quantitative data on haemopoietic stem cells1. The work reported here was designed to investigate the capacity of cells of various embryonic organs to populate the haemopoietic tissues of the irradiated embryo. The chick embryo is especially suited to such a study, first because haemopoietic cells can be injected intravenously into it, and second because the sex chromosome difference between male (ZZ) and female (ZW) cells provides a marker method for distinguishing the contributions of host and donor to haemopoietic recovery.

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References

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Authors and Affiliations

1. Department of Human Anatomy, University of Oxford,
   M. A. S. MOORE & J. J. T. OWEN

Authors

1. M. A. S. MOORE
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2. J. J. T. OWEN
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MOORE, M., OWEN, J. Chromosome Marker Studies in the Irradiated Chick Embryo.Nature 215, 1081–1082 (1967). https://doi.org/10.1038/2151081a0

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• Received: 19 June 1967
• Revised: 04 August 1967
• Issue Date: 02 September 1967
• DOI: https://doi.org/10.1038/2151081a0

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