Axon guidance mechanisms: semaphorins as simultaneous repellents and anti-repellents (original) (raw)

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• Published: October 1998

Nature Neuroscience volume 1, pages 436–439 (1998)Cite this article

Abstract

Semaphorins A and E are known to potently repel sympathetic axons. New work indicates that they can also antagonize the repellent action of semaphorin D at sensory axons.

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References

1. Tessier-Lavigne, M. & Goodman, C. S. Science 274, 1123–1133 (1996).
   Article CAS Google Scholar
2. Takahashi, T., Nakamura, F., Jin, Z., Kalb, R. G. & Strittmatter, S. M. Nature Neurosci. 1, 487– 493 (1998).
   Article CAS Google Scholar
3. Kolodkin, A. L. et al. Neuron 9, 831–845 (1992).
   Article CAS Google Scholar
4. Luo, Y.-L., Raible, D. & Raper, J. A. Cell 75, 217– 227 (1993).
   Article CAS Google Scholar
5. Kolodkin, A. L., Matthes, D. J. & Goodman, C. S. Cell 75, 1389– 1399 (1993).
   Article CAS Google Scholar
6. Mark, M. D., Lohrum, M. & Puschel, A. W. Cell Tissue Res. 290, 299– 306 (1997).
   Article CAS Google Scholar
7. Messersmith, E. K. et al. Neuron 14, 949–959 (1995).
   Article CAS Google Scholar
8. Taniguchi, M. et al. Neuron 19, 519–530 (1997).
   Article CAS Google Scholar
9. Takagi, S. et al. Neuron 7, 295–307 (1991).
   Article CAS Google Scholar
10. He, Z. & Tessier-Lavigne, M. Cell 90, 739–751 (1997).
    Article CAS Google Scholar
11. Kolodkin, A. L. et al. Cell 90, 753–762 (1997).
    Article CAS Google Scholar
12. Kitsukawa, T. et al. Neuron 19, 995–1005 (1997).
    Article CAS Google Scholar
13. Chen, H., Chedotal, A., He, Z., Goodman, C. S. & Tessier-Lavigne, M. Neuron 19, 547– 559 (1997).
14. Feiner, L., Koppel, A. M., Kobayashi, H. & Raper, J. A. Neuron 19, 539–545 (1997).
    Article CAS Google Scholar
15. Soker, S., Takashima, S., Miao, H. Q., Neufeld, G. & Klagsbrun, M. Cell 92, 735–745 (1998).
    Article CAS Google Scholar
16. Comeau, M. R. et al. Immunity 8, 473–482 (1998).
    Article CAS Google Scholar
17. Ohta, K. et al. Neuron 14, 1189–1199 (1995).
    Article CAS Google Scholar
18. Maestrini, E. Proc. Natl. Acad. Sci. USA 93, 674– 678 (1996).
    Article CAS Google Scholar
19. Xu, X. et al. J. Biol. Chem. 273, 22428– 22434 (1998).
    Article CAS Google Scholar

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Authors and Affiliations

1. Departments of Anatomy of Biochemistry and Biophysics, Howard Hughes Medical Institute, University of California, San Francisco, 94143-0452, California, USA
   Hang Chen, Zhigang He & Marc Tessier-Lavigne

Authors

1. Hang Chen
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2. Zhigang He
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3. Marc Tessier-Lavigne
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Chen, H., He, Z. & Tessier-Lavigne, M. Axon guidance mechanisms: semaphorins as simultaneous repellents and anti-repellents.Nat Neurosci 1, 436–439 (1998). https://doi.org/10.1038/2154

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• Issue Date: October 1998
• DOI: https://doi.org/10.1038/2154

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