Therapy of tuberculosis in mice by DNA vaccination (original) (raw)

References

  1. Kochi, A. Global challenge of tuberculosis. Lancet 44, 608–609 (1994).
    Google Scholar
  2. Bloom, B. R. & Fine, P. E. M. in Tuberculosis: Pathogenesis, Protection, and Control (ed. Bloom, B. R.) 531–557 (American Society for Microbiology, Washington DC, (1994).
    Book Google Scholar
  3. Hong Kong Chest Service & British Medical Research Council. Controlled trial of 4 three-times-weekly regimens and a daily regimen all given for 6 months for pulmonary tuberculosis. Second report: the results up to 24 months. Tubercle 63, 89–98 (1982).
    Article Google Scholar
  4. Young, D. B. & Duncan, K. Prospects for new interventions in the treatment and prevention of mycobacterial disease. Annu. Rev. Microbiol. 49, 641–673 (1995).
    Article CAS Google Scholar
  5. Tascon, R. E. et al. Vaccination against tuberculosis by DNA injection. Nature Med. 2, 888–892 (1996).
    Article CAS Google Scholar
  6. Huygen, K. et al. Immunogenicity and protective efficacy of a tuberculosis DNA vaccine. Nature Med. 2, 893–898 (1996).
    Article ADS CAS Google Scholar
  7. Zhu, X. J. et al. Functions and specificity of T cells following nucleic acid vaccination of mice against Mycobacterium tuberculosis infection. J. Immunol. 158, 5921–5926 (1997).
    CAS PubMed Google Scholar
  8. Bonato, V. L. D., Lima, V. M. F., Tascon, R. E., Lowrie, D. B. & Silva, C. L. Identification and characterization of protective T cells in hsp65 DNA vaccinated and Mycobacterium tuberculosis infected mice. Infect. Immun. 66, 169–175 (1998).
    CAS PubMed PubMed Central Google Scholar
  9. Stenger, S. et al. An antimicrobial activity of cytolytic T cells mediated by granulysin. Science 282, 121–125 (1998).
    Article ADS CAS Google Scholar
  10. Altare, F. et al. Impairment of mycobacterial immunity in human interleukin-12 receptor deficiency. Science 280, 1432–1435 (1998).
    Article ADS CAS Google Scholar
  11. Donnelly, J. J., Ulmer, J. B., Shiver, J. W. & Liu, M. A. DNA vaccines. Annu. Rev. Immunol. 15, 617–648 (1997).
    Article CAS Google Scholar
  12. Orme, I. M., Roberts, A. D., Griffin, J. P. & Abrams, J. S. Cytokine secretion by CD4 T-lymphocytes acquired in response to Mycobacterium tuberculosis infection. J. Immunol. 15, 518–525 (1993).
    Google Scholar
  13. Zhang, M. et al. T-cell cytokine responses in human infection with Mycobacterium tuberculosis. Infect. Immun. 63, 3231–3234 (1995).
    CAS PubMed PubMed Central Google Scholar
  14. Krieg, A. M., LoveHoman, L., Yi, A. K. & Harty, J. T. CpG DNA induces sustained IL-12 expression in vivo and resistance to Listeria monocyto genes challenge. J. Immunol. 161, 2428–2434 (1998).
    CAS PubMed Google Scholar
  15. Lai, W. C., Pakes, S. P., Ren, K., Lu, Y. S. & Bennett, M. Therapeutic effect of DNA immunization of genetically susceptible mice infected with virulent Mycoplasma pulmonis. J. Immunol. 158, 2513–2516 (1997).
    CAS PubMed Google Scholar
  16. Johnston, S. A. & Barry, M. A. Genetic to genomic vaccination. Vaccine 15, 808–809 (1997).
    Article CAS Google Scholar
  17. Lowrie, D. B., Silva, C. L., Colston, M. J., Ragno, S. & Tascon, R. E. Protection against tuberculosis by a plasmid DNA vaccine. Vaccine 15, 834–838 (1997).
    Article CAS Google Scholar
  18. Matsumoto, S. et al. Cloning and sequencing of a unique antigen MPT70 from Mycobacterium tuberculosis H37Rv and expression in BCG using E-coli Mycobacteria shuttle vector. Scand. J. Immunol. 41, 281–287 (1995).
    Article CAS Google Scholar
  19. Hewinson, R. G., Michell, S. L., Russell, W. P., McAdam, R. A. & Jacobs, W. R. Molecular characterization of MPT73: a seroreactive antigen of Mycobacterium tuberculosis with homology to MPT70. Scand. J. Immunol. 43, 490–499 (1996).
    Article CAS Google Scholar
  20. Trinchieri, G. Immunobiology of interleukin-12. Immunol. Res. 17, 269–278 (1998).
    Article CAS Google Scholar
  21. Flynn, J. L. et al. IL-12 increases resistance of BALB/c mice to Mycobacterium tuberculosis infection. J.Immunol. 155, 2515–2524 (1995).
    CAS PubMed Google Scholar
  22. Cooper, A. M., Magram, J., Ferrante, J. & Orme, I. M. Interleukin 12 (IL-12) is crucial to the development of protective immunity in mice intravenously infected with Mycobacterium tuberculosis. J. Exp. Med. 186, 39–45 (1997).
    Article CAS Google Scholar
  23. deJong, R. et al. Severe mycobacterial and Salmonella infections in interleukin-12 receptor-deficient patients. Science 280, 1435–1438 (1998).
    Article ADS CAS Google Scholar
  24. Mitchison, D. A. The action of antituberculosis drugs in short-course chemotherapy. Tubercle 66, 219–225 (1985).
    Article CAS Google Scholar
  25. McCune, R. M., Feldmann, F. M., Lambert, H. P. & McDermott, W. Microbial persistence. I. The capacity of tubercle bacilli to survive sterilization in mouse tissues. J. Exp. Med. 123, 445–468 (1966).
    Article CAS Google Scholar
  26. Wiegeshaus, E., Balasubramanian, V. & Smith, D. W. Immunity to tuberculosis from the perspective of pathogenesis. Infect. Immun. 57, 3671–3676 (1989).
    CAS PubMed PubMed Central Google Scholar
  27. Smith, P. G. & Moss, A. R. in Tuberculosis: Pathogenesis, Protection, and Control (ed. Bloom, B. R.) 47–59 (American Society for Microbiology, Washington DC, (1994).
    Book Google Scholar
  28. Tascon, R. E. et al. in Vaccine Design: The Role of Cytokine Networks (eds Gregoriadis, G., McCormack, B. & Allison, A. C.) 181–185 (Plenum, New York, (1997).
    Book Google Scholar
  29. Chapman, B. S., Thayer, R. M., Vincent, K. A. & Haigwood, N. L. Effect of intron A from human cytomegalovirus (Towne) immediate-early gene on heterologous expression in mammalian cells. Nucleic Acids Res. 19, 3979–3986 (1991).
    Article CAS Google Scholar
  30. Schultz, J., Pavlovic, J., Strack, B., Nawrath, M. & Moelling, K. Long-lasting anti-metastatic efficiency of IL-12-encoding plasmid DNA. Hum. Gene Ther. (in the press).

Download references