Conservative Mutations in Homologous Proteins (original) (raw)

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• Published: 23 May 1970

Nature volume 226, pages 753–754 (1970) Cite this article

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Abstract

IT has been argued that most of the evolutionary changes observed in homologous proteins are the result of chance fixation of selectively neutral mutations1,2. This hypothesis would be clarified by a more detailed analysis of observed patterns of amino-acid substitutions in related proteins than has been attempted previously3.

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References

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Authors and Affiliations

1. College of Physicians and Surgeons, Columbia University, Institute of Cancer Research, Francis Delafield Hospital, 99 Fort Washington Avenue, New York, 10032
   KARL W. LANKS & F. DAVID KITCHIN

Authors

1. KARL W. LANKS
2. F. DAVID KITCHIN

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LANKS, K., KITCHIN, F. Conservative Mutations in Homologous Proteins.Nature 226, 753–754 (1970). https://doi.org/10.1038/226753a0

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• Received: 08 September 1969
• Revised: 16 December 1969
• Issue date: 23 May 1970
• DOI: https://doi.org/10.1038/226753a0

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