Y chromosome effect on adult testis size (original) (raw)

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• Published: 09 August 1974

Nature volume 250, pages 499–500 (1974)Cite this article

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Abstract

DURING the development of mammals with X and Y chromosomes the Y chromosome brings about the differentiation of the gonad primordia into testes1. But apart from carrying the genetic determinants of maleness, little is known about its genetic constitution. In man, the gene for hairy tips to the ears shows Y linkage in at least some pedigrees2. In mice there is evidence for a Y-linked histocompatibility locus3,4, and for effects of the Y chromosome on the frequency of spermatozoa with abnormal heads5. Here we show that the size of the testes of adult mice is affected by factors on the Y chromosome.

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Authors and Affiliations

1. Applied Research of Cambridge, Ltd, 5 Jesus Lane, Cambridge, CB5 8BA, UK
   PETER HAYWARD
2. Institute of Genetics, University of Glasgow, Glasgow, G11 5JS, UK
   JOHN G. M. SHIRE

Authors

1. PETER HAYWARD
2. JOHN G. M. SHIRE

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HAYWARD, P., SHIRE, J. Y chromosome effect on adult testis size.Nature 250, 499–500 (1974). https://doi.org/10.1038/250499a0

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• Received: 29 April 1974
• Issue date: 09 August 1974
• DOI: https://doi.org/10.1038/250499a0

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