Albumin systematics of the extinct mammoth and Tasmanian wolf (original) (raw)

Nature volume 291, pages 409–411 (1981) Cite this article

Abstract

Knowledge of the molecular systematics of living species1–3 has provided a framework, independent of morphology, for evaluating the genetic relationships of living forms. Although amino acids have been found in many animal and plant fossils4, genetic information has generally not been obtained from the small amounts of surviving, chemically degraded protein. However, Westbroek _et al._5 have described immunological reactions to material from 60-Myr-old molluscs, and Lowenstein6,7 has reported the identification by radioimmunoassay (RIA) of species-specific collagen and serum factors in primate and bovine fossils. We report here the use of RIA to detect and characterize albumin in the soft tissues of two recently extinct species, the Siberian mammoth (Mammuthus primigenius) and the Tasmanian wolf (Thylacinus cynocephalus). Mammoth albumin was found to be very similar to, and immunologically equidistant from, the albumins of the two living species of elephants, Indian (Elephas maximus) and African (Loxodonta africana). Tasmanian wolf albumin stands in the same relationship to those of the two Australian marsupial dasyurids, Dasyurus and Dasyuroides.

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References

  1. Ayala, F. J. (ed.) Molecular Evolution (Sinauer, Sunderland, Massachusetts, 1976).
  2. Dayhoff, M. O. Atlas of Protein Sequence and Structure Vol. 5, Suppl. 3, (National Biomedical Research Foundation, Washington DC, 1978).
    Google Scholar
  3. Wilson, A. C., Carlson, S. S. & White, T. J. A. Rev. Biochem. 46, 573–639.
  4. Wyckoff, R. W. G. The Biochemistry of Animal Fossils (Scientechnica, Bristol, 1972).
    Google Scholar
  5. Westbroek, P. H. et al. Paleobiology 5, 151–167 (1979).
    Article CAS Google Scholar
  6. Lowenstein, J. M. in Biogeochemistry of Amino Acids (ed. Hare, P. E.) 41–52 (Wiley, New York, 1980).
    Google Scholar
  7. Lowenstein, J. M. Naturwissenschaften 67, 343–346 (1980).
    Article ADS CAS Google Scholar
  8. Tsu, T. T. & Herzenberg, L. A. in Selected Methods in Cellular Immunology (eds Mishell, B. B. & Shiigi, S. M.) Ch. 18 (Freeman, San Francisco, 1980).
    Google Scholar
  9. Sarich, V. M. Syst. Zool. 18, 286–295 (1969).
    Article CAS Google Scholar
  10. Sarich, V. M. & Cronin, J. E. in Molecular Anthropology (eds Goodman, M. & Tashian, R. E.) 141–170 (Plenum, New York, 1976).
    Book Google Scholar
  11. Sarich, V. M. Nature 265, 24–28 (1977).
    Article ADS CAS Google Scholar
  12. Sarich, V. M. Nature 245, 218–220 (1973).
    Article ADS Google Scholar
  13. Prager, E. M., Wilson, A. C., Lowenstein, J. M. & Sarich, V. M. Science 209, 287–289 (1980).
    Article ADS CAS Google Scholar
  14. Coppens, Y., Maglio, V. J., Madden, C. T. & Beden, M. in Evolution of African Mammals (eds Maglio, V. J. & Cooke, H. B. S.) 336–367 (Harvard University Press, 1978).
    Google Scholar
  15. Bensley, B. A. Trans. Linn. Soc. London (Zool.) 9, 83–217 (1903).
    Article Google Scholar
  16. Sinclair, W. J. Rep. Princeton Univ. exped. Patagonia 4, 333–460 (1906).
    Google Scholar
  17. Archer, M. J. Linn. Soc. 59(3), 217–322 (1976).
    Article Google Scholar
  18. Archer, M. Aust. J. Zool. Suppl. Ser. 39, 1–34 (1976).
    Article Google Scholar
  19. Simpson, G. G. Am. Mus. Novit. 1118, 1–6 (1941).
    Google Scholar
  20. Marshall, L. G. Syst. Zool. 26, 410–425 (1977).
    Article Google Scholar
  21. Maxson, L. R., Sarich, V. M. & Wilson, A. C. Nature 255, 397–400 (1975).
    Article ADS Google Scholar

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Authors and Affiliations

  1. Department of Medicine (122 MR2), University of California, San Francisco, California, 94143, USA
    Jerold M. Lowenstein
  2. Departments of Anthropology and Biochemistry, University of California, Berkeley, California, 94720, USA
    Vincent M. Sarich
  3. Department of Population Biology, The Australian National University, Canberra City, ACT, 2600, Australia
    Barry J. Richardson

Authors

  1. Jerold M. Lowenstein
  2. Vincent M. Sarich
  3. Barry J. Richardson

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Lowenstein, J., Sarich, V. & Richardson, B. Albumin systematics of the extinct mammoth and Tasmanian wolf.Nature 291, 409–411 (1981). https://doi.org/10.1038/291409a0

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