Pump up the versatility (original) (raw)

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• Published: 31 August 2000

Bacterial genomics

Nature volume 406, pages 947–948 (2000) Cite this article

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Traditional approaches have not provided us with the tools needed to fight this bacterium effectively. For reasons that are not clear, P. aeruginosa infections resist treatment with antibiotics. Hence the hope that the P. aeruginosa genome sequence1 will reveal new ways of tackling this organism.

The completed sequence, described by Stover and colleagues, is the result of a unique collaboration between a group of academic investigators, a pharmaceutical company and a charitable foundation, the US Cystic Fibrosis Foundation. The project, which began three years ago, was financed jointly by the Cystic Fibrosis Foundation and the company PathoGenesis, and has proven to be a model of scientific integrity and interaction.

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Figure 1: The rod-shaped Pseudomonas aeruginosa on cultured epithelial cells from the human respiratory tract.

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References

1. Stover, C. K. et al. Nature 406, 959–964 (2000).
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3. The Pseudomonas Genome Project. http://www.pseudomonas.com/
4. Nikaido, H. Clin. Infect. Dis. 27, S32–S41 (1998).
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5. Costerton, W. C., Stewart, P. & Greenberg, E. P. Science 284, 1318– 1322 (1999).
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Authors and Affiliations

1. Department of Microbiology College of Medicine, University of Iowa, Iowa City, 52242-1109, Iowa, USA
   E. Peter Greenberg

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1. E. Peter Greenberg

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Correspondence toE. Peter Greenberg.

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Greenberg, E. Pump up the versatility.Nature 406, 947–948 (2000). https://doi.org/10.1038/35023203

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• Issue date: 31 August 2000
• DOI: https://doi.org/10.1038/35023203

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