Cell-fate conversion of lymphoid-committed progenitors by instructive actions of cytokines (original) (raw)

References

  1. Fairbairn, L. J., Cowling, G. J., Reipert, B. M. & Dexter, T. M. Suppression of apoptosis allows differentiation and development of a multipotent hemopoietic cell line in the absence of added growth factors. Cell 74, 823–832 ( 1993).
    Article CAS Google Scholar
  2. Ogawa, M. Differentiation and proliferation of hematopoietic stem cells. Blood 81, 2844–2853 ( 1993).
    CAS PubMed Google Scholar
  3. Watowich, S. S. et al. Cytokine receptor signal transduction and the control of hematopoietic cell development. Annu. Rev. Cell Dev. Biol. 12, 91–128 (1996).
    Article CAS Google Scholar
  4. Metcalf, D. Stem cells, pre-progenitor cells and lineage-committed cells: are our dogmas correct? Ann. NY Acad. Sci. 872, 289– 303 (1999); discussion 872, 303–304 (1999).
    Article ADS CAS Google Scholar
  5. Kondo, M., Weissman, I. L. & Akashi, K. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 91, 661– 672 (1997).
    Article CAS Google Scholar
  6. Ogasawara, K. et al. Requirement for IRF-1 in the microenvironment supporting development of natural killer cells. Nature 391, 700 –703 (1998); erratum 392, 843 (1998).
    Article ADS CAS Google Scholar
  7. Lodolce, J. P. et al. IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. Immunity 9, 669–676 (1998).
    Article CAS Google Scholar
  8. Kennedy, M. K. et al. Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. J. Exp. Med. 191, 771–780 (2000).
    Article CAS Google Scholar
  9. Giri, J. G. et al. Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15. EMBO J. 13, 2822–2830 (1994).
    Article CAS Google Scholar
  10. Sugamura, K. et al. The interleukin-2 receptor gamma chain: its role in the multiple cytokine receptor complexes and T cell development in XSCID. Annu. Rev. Immunol. 14, 179–205 (1996).
    Article CAS Google Scholar
  11. Kondo, M. et al. Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4. Science 262, 1874–1877 (1993).
    Article ADS CAS Google Scholar
  12. Nemoto, T. et al. Differences in the interleukin-2 (IL-2) receptor system in human and mouse: alpha chain is required for formation of the functional mouse IL-2 receptor. Eur. J. Immunol. 25, 3001 –3005 (1995).
    Article CAS Google Scholar
  13. Asano, M. et al. IL-2 can support growth of CD8+ T cells but not CD4+ T cells of human IL-2 receptor beta-chain transgenic mice. J. Immunol. 153, 5373–5381 ( 1994).
    CAS PubMed Google Scholar
  14. Nakano, T., Kodama, H. & Honjo, T. Generation of lymphohematopoietic cells from embryonic stem cells in culture. Science 265, 1098 –1101 (1994).
    Article ADS CAS Google Scholar
  15. Domen, J., Gandy, K. L. & Weissman, I. L. Systemic overexpression of BCL-2 in the hematopoietic system protects transgenic mice from the consequences of lethal irradiation. Blood 91, 2272–2282 (1998).
    CAS PubMed Google Scholar
  16. Henry, C., Marbrook, J., Vann, D. C., Kodlin, D. & Wofsy, C. in Selected Methods in Cellular Immunology (eds Mishell, B. B. & Shiigi, S. M.) 138– 152 (WH Freeman, San Francisco, 1981).
    Google Scholar
  17. Schlissel, M. S. & Stanhope-Baker, P. Accessibility and the developmental regulation of V(D)J recombination. Semin. Immunol. 9, 161–170 ( 1997).
    Article CAS Google Scholar
  18. Hatakeyama, M., Mori, H., Doi, T. & Taniguchi, T. A restricted cytoplasmic region of IL-2 receptor beta chain is essential for growth signal transduction but not for ligand binding and internalization. Cell 59, 837–845 ( 1989).
    Article CAS Google Scholar
  19. Nelson, B. H. & Willerford, D. M. Biology of the interleukin-2 receptor. Adv. Immunol. 70, 1– 81 (1998).
    Article CAS Google Scholar
  20. Constantinescu, S. N., Ghaffari, S. & Lodish, H. F. The erythropoietin receptor: structure, activation and intracellular signal transduction. Trends Endocrinol. Metab. 10, 18–23 ( 1999).
    Article CAS Google Scholar
  21. Watanabe, S. et al. Reconstituted human granulocyte-macrophage colony-stimulating factor receptor transduces growth-promoting signals in mouse NIH 3T3 cells: comparison with signalling in BA/F3 pro-B cells. Mol. Cell. Biol. 13, 1440–1448 ( 1993).
    Article CAS Google Scholar
  22. Ha, K., Minden, M., Hozumi, N. & Gelfand, E. W. Immunoglobulin gene rearrangement in acute myelogenous leukemia. Cancer Res. 44, 4658–4660 (1984).
    CAS PubMed Google Scholar
  23. Palumbo, A., Minowada, J., Erikson, J., Croce, C. M. & Rovera, G. Lineage infidelity of a human myelogenous leukemia cell line. Blood 64, 1059– 1063 (1984).
    CAS PubMed Google Scholar
  24. Cheng, G. Y., Minden, M. D., Toyonaga, B., Mak, T. W. & McCulloch, E. A. T cell receptor and immunoglobulin gene rearrangements in acute myeloblastic leukemia. J. Exp. Med. 163, 414–424 ( 1986).
    Article CAS Google Scholar
  25. Godfrey, D. I., Kennedy, J., Mombaerts, P., Tonegawa, S. & Zlotnik, A. Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8- thymocyte differentiation. J. Immunol. 152 , 4783–4792 (1994).
    CAS PubMed Google Scholar
  26. Hardy, R. R., Carmack, C. E., Shinton, S. A., Kemp, J. D. & Hayakawa, K. Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow. J. Exp. Med. 173, 1213–1225 (1991).
    Article CAS Google Scholar
  27. Rolink, A. et al. A subpopulation of B220+ cells in murine bone marrow does not express CD19 and contains natural killer cell progenitors. J. Exp. Med. 183, 187–194 (1996).
    Article CAS Google Scholar
  28. Ghaffari, S. et al. BCR-ABL and v-SRC tyrosine kinase oncoproteins support normal erythroid development in erythropoietin receptor-deficient progenitor cells. Proc. Natl Acad. Sci. USA 96, 13186– 13190 (1999).
    Article ADS CAS Google Scholar

Download references