The proteins of linked genes evolve at similar rates (original) (raw)

• Wolfe, K. H. & Sharp, P. M. Mammalian gene evolution: nucleotide sequence divergence between mouse and rat. J. Mol. Evol. 37, 441–456 (1993).
  Article ADS CAS Google Scholar
• Wilson, A. C., Carlson, S. S. & White, T. J. Biochemical evolution. Ann. Rev. Biochem. 46, 573–639 ( 1977).
  Article CAS Google Scholar
• Hurst, L. D. & Smith, N. G. C. Do essential genes evolve slowly? Curr. Biol. 9, 747–750 (1999).
  Article CAS Google Scholar
• Graur, D. Amino-acid composition and the evolutionary rates of protein-coding genes. J. Mol. Evol. 22, 53–62 (1985).
  Article ADS CAS Google Scholar
• Tourasse, N. J. & Li, W. -H. Selective constraints, amino acid composition, and the rate of protein evolution. Mol. Biol. Evol. 17, 656–664 (2000).
  Article CAS Google Scholar
• Kuma, K., Iwabe, N. & Miyata, T. Functional constraints against variations on molecules from the tissue-level—slowly evolving brain-specific genes demonstrated by protein-kinase and immunoglobulin supergene families. Mol. Biol. Evol. 12, 123–130 ( 1995).
  Article CAS Google Scholar
• Hughes, A. L. Circumsporozoite protein genes of malaria parasites (Plasmodium spp.): evidence for positive selection on immunogenic regions. Genetics 127, 345–353 ( 1991).
  CAS PubMed PubMed Central Google Scholar
• Tsaur, S. C. & Wu, C. I. Positive selection and the molecular evolution of a gene of male reproduction, Acp26Aa of Drosophila. Mol. Biol. Evol. 14, 544–549 (1997).
  Article CAS Google Scholar
• Hurst, L. D. & McVean, G. T. Do we understand the evolution of genomic imprinting? Curr. Opin. Genet. Dev. 8, 701–708 (1998).
  Article CAS Google Scholar
• Wyckoff, G. J., Wang, W. & Wu, C. I. Rapid evolution of male reproductive genes in the descent of man. Nature 403, 304–309 ( 2000).
  Article ADS CAS Google Scholar
• Makalowski, W. & Boguski, M. S. Synonymous and nonsynonymous substitution distances are correlated in mouse and rat genes. J. Mol. Evol. 47, 119– 121 (1998).
  Article ADS CAS Google Scholar
• Smith, N. G. C. & Hurst, L. D. The effect of tandem substitutions on the correlation between synonymous and nonsynonymous rates in rodents. Genetics 153, 1395– 1402 (1999).
  CAS PubMed PubMed Central Google Scholar
• Matassi, G., Sharp, P. M. & Gautier, C. Chromosomal location effects on gene sequence evolution in mammals. Curr. Biol. 9, 786– 791 (1999).
  Article CAS Google Scholar
• Silver, L. M. Mouse Genetics (Oxford Univ. Press, Oxford, 1995).
  Google Scholar
• Casane, D., Boissinot, S., Chang, B. H. J., Shimmin, L. C. & Li, W. H. Mutation pattern variation among regions of the primate genome. J. Mol. Evol. 45, 216–226 (1997).
  Article ADS CAS Google Scholar
• Averof, M., Rokas, A., Wolfe, K. & Sharp, P. M. Evidence for a high frequency of double-nucleotide substitutions. Science 287, 1283–1286 (2000).
  Article ADS CAS Google Scholar
• Caccio, S. et al. Methylation patterns in the isochores of vertebrate genomes. Gene 205, 119–124 (1997).
  Article CAS Google Scholar
• Cargill, M. et al. Characterization of single-nucleotide polymorphisms in coding regions of human genes. Nature Genet. 22, 231–238 (1999).
  Article CAS Google Scholar
• Nordborg, M., Charlesworth, B. & Charlesworth, D. The effect of recombination on background selection. Genet. Res. 67, 159–174 (1996).
  Article CAS Google Scholar
• Nachman, M. W. & Churchill, G. A. Heterogeneity in rates of recombination across the mouse genome. Genetics 142, 537–548 (1996).
  CAS PubMed PubMed Central Google Scholar
• Eyre-Walker, A. Recombination and mammalian genome evolution. Proc. R. Soc. London Ser. B 252, 237–243 ( 1993).
  Article ADS CAS Google Scholar
• Bernardi, G. The human genome: organization and evolutionary history. Annu. Rev. Genet. 29, 445–476 (1995).
  Article CAS Google Scholar
• Drouin, R., Holmquist, J. P. & Richer, C. L. High-resolution replication bands compared with morphologic G- and R-bands. Adv. Hum. Genet. 22, 47– 115 (1994).
  Article CAS Google Scholar
• Bernardi, G. et al. The mosaic genome of warm-blooded vertebrates. Science 228, 953–958 ( 1985).
  Article ADS CAS Google Scholar
• Galtier, N. & Mouchiroud, D. Isochore evolution in mammals: A human-like ancestral structure. Genetics 150, 1577–1584 (1998).
  CAS PubMed PubMed Central Google Scholar
• Duret, L., Mouchiroud, D. & Gouy, M. HOVERGEN—a database of homologous vertebrate genes. Nucleic Acid Res. 22, 2360– 2365 (1994).
  Article CAS Google Scholar
• Smith, N. G. C. & Hurst, L. D. The causes of synonymous rate variation in the rodent genome: Can substitution rates be used to estimate the sex bias in mutation rate? Genetics 152, 661–673 (1999).
  CAS PubMed PubMed Central Google Scholar
• Li, W. -H. Unbiased estimation of the rates of synonymous and nonsynonymous substitution. J. Mol. Evol. 36, 96–99 (1993).
  Article ADS CAS Google Scholar
• Pamilo, P. & Bianchi, N. O. Evolution of the Zfx and Zfy genes: rates and interdependence between the genes. Mol. Biol. Evol. 10, 271–281 ( 1993).
  CAS PubMed Google Scholar