Functional genomic analysis of C. elegans chromosome I by systematic RNA interference (original) (raw)
References
The C. elegans Sequencing Consortium. Genome sequence of the nematode C. elegans: a platform for investigating biology. Science282, 2012– 2018 (1998). ArticleADS Google Scholar
Adams, M. D. et al. The genome sequence of Drosophila melanogaster. Science287, 2185–2195 ( 2000). Article Google Scholar
Rubin, G. M. et al. Comparative genomics of the eukaryotes. Science287, 2204–2215 ( 2000). ArticleCAS Google Scholar
Fire, A. et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature391, 806–811 (1998). ArticleADSCAS Google Scholar
Tabara, H., Grishok, A. & Mello, C. C. RNAi in C. elegans: soaking in the genome sequence. Science282, 430– 431 (1998). ArticleCAS Google Scholar
Timmons, L. & Fire, A. Specific interference by ingested dsRNA. Nature395, 854 ( 1998). ArticleADSCAS Google Scholar
Kamath, R. S., Martinez-Campos, M., Zipperlen, P., Fraser, A. G. & Ahringer, J. Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in C. elegans. Genome Biol. (in the press).
Lefebvre, S. et al. Identification and characterization of a spinal muscular atrophy-determining gene. Cell80, 155–165 (1995). ArticleCAS Google Scholar
Bowerman, B. & Shelton, C. A. Cell polarity in the early Caenorhabditis elegans embryo. Curr. Opin. Genet. Dev.9, 390–395 (1999). ArticleCAS Google Scholar
Bargmann, C. I. Neurobiology of the Caenorhabditis elegans genome. Science282, 2028–2033 ( 1998). ArticleADSCAS Google Scholar
Kim, J. G. & Hudson, L. D. Novel member of the zinc finger superfamily: A C2-HC finger that recognizes a glia-specific gene. Mol. Cell Biol.12, 5632–5639 (1992). ArticleCAS Google Scholar
Armstrong, R. C., Kim, J. G. & Hudson, L. D. Expression of myelin transcription factor I (MyTI), a “zinc-finger” DNA- binding protein, in developing oligodendrocytes. Glia14, 303–321 (1995). ArticleCAS Google Scholar
Kim, J. G. et al. Myelin transcription factor 1 (Myt1) of the oligodendrocyte lineage, along with a closely related CCHC zinc finger, is expressed in developing neurons in the mammalian central nervous system. J. Neurosci. Res.50, 272–290 ( 1997). ArticleCAS Google Scholar
Strumpf, D. & Volk, T. Kakapo, a novel cytoskeletal-associated protein is essential for the restricted localization of the neuregulin-like factor, vein, at the muscle-tendon junction site. J. Cell Biol.143, 1259–1270 ( 1998). ArticleCAS Google Scholar
Gregory, S. L. & Brown, N. H. kakapo, a gene required for adhesion between and within cell layers in Drosophila , encodes a large cytoskeletal linker protein related to plectin and dystrophin. J. Cell Biol.143, 1271– 1282 (1998). ArticleCAS Google Scholar
Lee, S., Harris, K. L., Whitington, P. M. & Kolodziej, P. A. short stop is allelic to kakapo, and encodes rod-like cytoskeletal-associated proteins required for axon extension. J. Neurosci.20, 1096–1108 (2000). ArticleCAS Google Scholar
Prokop, A., Uhler, J., Roote, J. & Bate, M. The kakapo mutation affects terminal arborization and central dendritic sprouting of Drosophila motorneurons. J. Cell Biol.143, 1283–1294 (1998). ArticleCAS Google Scholar
Burridge, K. & Connell, L. Talin: a cytoskeletal component concentrated in adhesion plaques and other sites of actin-membrane interaction. Cell Motil.3, 405–417 (1983). ArticleCAS Google Scholar
Hodgkin, J. Sex, cell death, and the genome of C. elegans. Cell98, 277–280 (1999). ArticleCAS Google Scholar
McNally, F. J. & Vale, R. D. Identification of katanin, an ATPase that severs and disassembles stable microtubules. Cell75, 419–429 ( 1993). ArticleCAS Google Scholar
Srayko, M., Buster, D. W., Bazirgan, O. A., McNally, F. J. & Mains, P. E. MEI-1/MEI-2 katanin-like microtubule severing activity is required for Caenorhabditis elegans meiosis. Genes Dev.14, 1072–1084 (2000). CASPubMedPubMed Central Google Scholar
Altschul, S. F., Gish, W., Miller, W., Myers, E. W. & Lipman, D. J. Basic local alignment search tool. J. Mol. Biol.215, 403–410 ( 1990). ArticleCAS Google Scholar
Barnes, T. M., Kohara, Y., Coulson, A. & Hekimi, S. Meiotic recombination, noncoding DNA and genomic organization in Caenorhabditis elegans. Genetics141, 159–179 ( 1995). CASPubMedPubMed Central Google Scholar
Goffeau, A. et al. Life with 6000 genes. Science274, 563–567 (1996). Article Google Scholar
Mewes, H. W. et al. MIPS: a database for genomes and protein sequences. Nucleic Acids Res.28, 37–40 (2000). ArticleADSCAS Google Scholar
Svetlov, V. V. & Cooper, T. G. Review: compilation and characteristics of dedicated transcription factors in Saccharomyces cerevisiae. Yeast11, 1439– 1484 (1995). ArticleCAS Google Scholar
Hodgkin, J. & Herman, R. K. Changing styles in C. elegans genetics. Trends Genet.14, 352– 357 (1998). ArticleCAS Google Scholar
Chen, J. J. et al. Profiling expression patterns and isolating differentially expressed genes by cDNA microarray system with colorimetry detection. Genomics51, 313–324 ( 1998). ArticleCAS Google Scholar
Walhout, A. J. et al. Protein interaction mapping in C. elegans using proteins involved in vulval development. Science287, 116–122 (2000). ArticleADSCAS Google Scholar
Schuler, G. D. Sequence mapping by electronic PCR. Genome Res.7, 541–550 (1997). ArticleCAS Google Scholar
Altschul, S. F. et al. Gapped BLAST and PSI–BLAST: a new generation of protein database search programs. Nucleic Acids Res.25, 3389–3402 (1997). ArticleCAS Google Scholar