At the interfaces of epidemiology, genetics and genomics (original) (raw)
Doll, R. & Hill, A. B. A study of the aetiology of carcinoma of the lung. Br. Med. J.2, 1271– 1286 (1952). ArticleCAS Google Scholar
Beaty, T. H. & Khoury, M. J. Interface of genetics and epidemiology . Epidemiol. Rev.22, 120– 125 (2000). ArticleCAS Google Scholar
Holtzman, N. A. & Martineau, T. M. Will genetics revolutionize medicine? N. Engl. J. Med.343, 141–144 (2000). ArticleCAS Google Scholar
Perou, C. M. et al. Molecular portraits of human breast tumours. Nature406, 747–752 ( 2000). ArticleCAS Google Scholar
Vogelstein, B. et al. Allelotype of colorectal carcinomas. Science244, 207–211 (1989). ArticleCAS Google Scholar
Alon, U. et al. Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays. Proc. Natl Acad. Sci. USA96, 6745– 6750 (1999). ArticleCAS Google Scholar
Prevo, L. J., Sanchez, C. A., Galipeau, P. C. & Reid, B. J. _p53_-mutant clones and field effects in Barrett's esophagus. Cancer Res.59, 4784–4787 (1999). CASPubMed Google Scholar
Golub, T. R. et al. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science286 , 531–536 (1999). ArticleCAS Google Scholar
Hopper, J. L. et al. Population-based estimate of the average age-specific cumulative risk of breast cancer for a defined set of protein-truncating mutations in BRCA1 and BRCA2. Cancer Epidemiol. Biomarkers Prev.8, 741–747 ( 1999). CASPubMed Google Scholar
Friedman, L. et al. The search for BRCA1. Cancer Res.54, 6374–6382 (1994). CASPubMed Google Scholar
Struewing, J. et al. The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews. N. Engl. J. Med.336, 1401–1408 ( 1997). ArticleCAS Google Scholar
Warner, E. et al. Prevalence and penetrance of BRCA1 and BRCA2 gene mutations in unselected Ashkenazi Jewish women with breast cancer. J. Natl Cancer Instit.91, 1241–1247 (1999). PubMed ArticleCAS Google Scholar
Peto, J. et al. Prevalence of BRCA1 and BRCA2 gene mutations in patients with early-onset breast cancer. J. Natl Cancer Inst.91, 943–949 (1999). ArticleCAS Google Scholar
Malone, K. E. et al. Frequency of BRCA1/BRCA2 mutations in a population-based sample of young breast carcinoma cases. Cancer88, 1393–1402 (2000). ArticleCAS Google Scholar
Newman, B. et al. Frequency of breast cancer attributable to BRCA1 in a population-based series of American women. J. Am. Med. Assoc.279, 915–921 ( 1998). PubMed ArticleCAS Google Scholar
Hansen, M. F. et al. Osteosarcoma and retinoblastoma: a shared chromosomal mechanism reveals recessive predisposition. Proc. Natl Acad. Sci. USA82, 6216–6220 (1985). ArticleCAS Google Scholar
Onadim, Z., Hogg, A., Baird, P. N. & Cowell, J. K. Oncogenic point mutations in exon 20 of the RB1 gene in families showing incomplete penetrance and mild expression of the retinoblastoma phenotype. Proc. Natl Acad. Sci. USA89, 6177– 6181 (1992). ArticleCAS Google Scholar
Otterson, G. A., Chen, W. -d., Coxon, A. B., Khleif, S. N. & Kaye, F. J. Incomplete penetrance of familial retinoblastoma linked to germ-line mutations that result in partial loss of RB function. Proc. Natl Acad. Sci. USA94, 12036–12040 (1997). ArticleCAS Google Scholar
MacPhee, M. et al. The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of APC Min-induced intestinal neoplasia. Cell81, 957–966 ( 1995). ArticleCAS Google Scholar
Takaku, K. et al. Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes. Cell92, 645–656 (1998). ArticleCAS Google Scholar
Laird, P. W. et al. Suppression of intestinal neoplasia by DNA hypomethylation . Cell81, 197–205 (1995). ArticleCAS Google Scholar
Lynch, H. & de la Chapelle, A. Cancer susceptibility to non-polyposis colorectal cancer. J. Med. Genet.36, 801–818 (1999). CASPubMedPubMed Central Google Scholar
Yan, H. et al. Conversion of diploidy to haploidy. Nature403, 723–724 (2000). ArticleCAS Google Scholar
Warthin, A. S. Heredity with reference to carcinoma. Arch. Int. Med.12, 546–555 (1913). Article Google Scholar
Lynch, H. T., Lynch, P. M., Albana, W. A. & Lynch, J. F. The cancer syndrome: a status report. Dis. Col. Rect.24, 311–322 (1981). ArticleCAS Google Scholar
Coleman, M. P., Esteve, J., Damiecki, P., Arslan, A. & Renard, H. Trends in Cancer Incidence and Mortality (Oxford Univ. Press, Lyon, 1993). Google Scholar
Potter, J. D. Colorectal cancer: molecules and populations. J. Natl Cancer Inst.91, 916–932 ( 1999). ArticleCAS Google Scholar
Taylor, J. et al. The role of _N_-acetylation polymorphisms in smoking-associated bladder cancer: evidence of a gene-gene-exposure three-way interaction. Cancer Res.58, 3603–3610 (1998). CASPubMed Google Scholar
Potter, J. D. et al. Colorectal adenomatous and hyperplastic polyps: smoking and _N_-Acetyltransferase 2 polymorphisms. Cancer Epidemiol. Biomarkers Prev.8, 69–75 ( 1999). CASPubMed Google Scholar
Ulrich, C. et al. Colorectal adenomas and the C677T MTHFR polymorphism: Evidence for gene-environment interaction? Cancer Epidemiol. Biomarkers Prev.8, 659–668 ( 1999). CASPubMed Google Scholar
Marcus, P. M. et al. Cigarette smoking, _N_-acetyltransferase 2 acetylation status, and bladder cancer risk: a case-series meta-analysis of a gene-environment interaction. Cancer Epidemiol. Biomarkers Prev.9, 461–467 (2000). CASPubMed Google Scholar
Jarvik, G. Genetic predictors of common disease: apolipoprotein E genotype as a paradigm . Ann. Epidemiol.7, 357– 362 (1997). ArticleCAS Google Scholar
Altshuler, D. et al. The common PPARγ pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nature Genet.26, 76–79 (2000). ArticleCAS Google Scholar
Sing, C. F. & Davignon, J. Role of the apolipoprotein E polymorphism in determining normal plasma lipid and lipoprotein variation. Am. J.Hum. Genet.37, 268–285 (1985). CASPubMedPubMed Central Google Scholar