Coley's toxins in perspective (original) (raw)

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• Published: 07 May 1992

Nature volume 357, pages 11–12 (1992) Cite this article

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Despite initial hopes, the efficacy of tumour necrosis factor in treating cancer patients has been disappointing. But a more careful selection of patients, and more appropriate treatment, might be fruitful.

References

1. Coley, W. B. Practitioner 83, 589–613 (1909).
   Google Scholar
2. Nauts, H. C. et al. Can. Res. 6, 205–216 (1946).
   CAS Google Scholar
3. Harmer, T. W. Boston Med. Surg. J. 171, 253 (1914).
   Article Google Scholar
4. Johnston, B. J. & Novales, E. T. Can. Chem. Rep. No. 21, 43–68 (1962).
5. Axelrod, R. S. et al. Cancer 61, 2219–2230 (1988).
   Article CAS Google Scholar
6. Tichatschek, E. et al. Can. Immun. Immunother. 27, 278–282 (1988).
   CAS Google Scholar
7. Berendt, M. J. et al. J. exp. Med. 148, 1560 (1978).
   Article CAS Google Scholar
8. Demetri, G. D. et al. J. clin. Oncol. 7, 1545 (1989).
   Article CAS Google Scholar
9. Spriggs, D. R. & Yates, S. W. in Tumor Necrosis Factors (ed. Beutler, B.) 394 (Raven, New York, 1992).
   Google Scholar
10. Carswell, E. A. et al. Proc. natn. Acad. Sci. U.S.A. 72, 3666–3670 (1975).
    Article ADS CAS Google Scholar
11. McIntosh, J. K. et al. Can. Res. 49, 1408–1414 (1989).
    CAS Google Scholar

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Authors and Affiliations

1. Amgen, Inc., 1840 Dehavillard Drive, Thousand Oaks, California, 91320–1789, USA
   Charlie O. Starnes

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1. Charlie O. Starnes

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Starnes, C. Coley's toxins in perspective.Nature 357, 11–12 (1992). https://doi.org/10.1038/357011a0

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• Issue date: 07 May 1992
• DOI: https://doi.org/10.1038/357011a0