Short-range control of cell differentiation in the Arabidopsis root meristem (original) (raw)

Nature volume 390, pages 287–289 (1997)Cite this article

Abstract

Meristems are distinctive regions of plants that have capacity for continuous growth. Their developmental activity generates the majority of plant organs1. It is currently unknown how cell division and cell differentiation are orchestrated in meristems, although genetic studies have demonstrated the relevance of a proper balance between the two processes2,3,4,5,6. Root meristems contain a distinct central region of mitotically inactive cells, the quiescent centre7, the function of which has remained elusive until now. Here we present laser ablation and genetic data that show that in Arabidopsis thaliana the quiescent centre inhibits differentiation of surrounding cells. Differentiation regulation occurs within the range of a single cell, in a manner strikingly similar to examples in animal development, such as during delamination of Drosophila neuroblasts8. Our data indicate that pattern formation in the root meristem is controlled by a balance between short-range signals inhibiting differentiation and signals that reinforce cell fate decisions9.

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Acknowledgements

We thank W. Hage for assistance with the confocal microscope; P. Westers for statistical analysis; D. Smit, F. Kuyer and B. Landman for artwork; F. Kindt, R. Leitho, W. Veenendaal and P. Brouwer for photography; and H. I. McKhann and P. Benfey for useful suggestions on the manuscript. C.v.d.B. was sponsored by a grant from the Dutch Organisation of Life Sciences (SLW).

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Authors and Affiliations

  1. Department of Molecular Cell Biology, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
    Claudia van den Berg, Viola Willemsen, Giel Hendriks, Peter Weisbeek & Ben Scheres

Authors

  1. Claudia van den Berg
  2. Viola Willemsen
  3. Giel Hendriks
  4. Peter Weisbeek
  5. Ben Scheres

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Correspondence toBen Scheres.

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van den Berg, C., Willemsen, V., Hendriks, G. et al. Short-range control of cell differentiation in the Arabidopsis root meristem.Nature 390, 287–289 (1997). https://doi.org/10.1038/36856

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