Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene (original ) (raw ) References
White, M. F., Maron, R. & Kahn, C. R. Nature 318 , 183–186 (1985).Article ADS CAS PubMed Google Scholar
White, M. F. & Kahn, C. R. J. biol. Chem. 269 , 1–5 (1994).CAS PubMed Google Scholar
Keller, S. R., Kitagawa, K., Aebersold, R., Lienhard, G. E. & Garner, C. W. J. biol. Chem. 266 , 12817–12820 (1991).CAS PubMed Google Scholar
Sun, X. J. et al. Nature 352 , 73–77 (1991).Article ADS CAS PubMed Google Scholar
Araki, E., Haag, B. L. & Kahn, C. R. Biochim. biophys. Acta 1221 , 353–356 (1994).Article CAS PubMed Google Scholar
Araki, E. et al. Diabetes 42 , 1041–1054 (1993).Article CAS PubMed Google Scholar
Beguinot, F., Kahn, C. R., Moses, A. C., White, M. F. & Smith, R. J. Endocrinology 125 , 1599–1605 (1989).Article CAS PubMed Google Scholar
Ruderman, N., Kapeller, R., White, M. F. & Cantley, L. C. Proc. natn. Acad. Sci. U.S.A. 87 , 1411–1415 (1990).Article ADS CAS Google Scholar
Sun, X. J. et al. J. biol. Chem. 267 , 22662–22672 (1992).CAS PubMed Google Scholar
Giorgetti, S., Ballotti, R., Kowalski-Chauvel, A., Tartare, S. & Van Obberghen, E. J. biol. Chem. 268 , 7358–7364 (1993).CAS PubMed Google Scholar
Folli, F., Saad, M. J. A., Backer, J. M. & Kahn, C. R. J. biol. Chem. 267 , 22171–22177 (1992).CAS PubMed Google Scholar
Skolnik, E. Y. et al. Science 260 , 1953–1955 (1993).Article ADS CAS PubMed Google Scholar
Chuang, L. M. et al. Molec. cell. Biol. 13 , 6653–6660 (1993).Article CAS PubMed PubMed Central Google Scholar
Kuhne, M. R., Pawson, T., Lienhard, G. E. & Feng, G.-S. J. biol. Chem. 268 , 11479–11481 (1993).CAS PubMed Google Scholar
Saad, M. J. A. et al. J. clin. Invest. 90 , 1839–1849 (1992).Article CAS PubMed PubMed Central Google Scholar
Sung, C. K., Sanchez-Margalet, V. & Goldfine, I. D. J. biol. Chem. 269 , 12503–12507 (1994).CAS PubMed Google Scholar
Kovacina, K. S. & Roth, R. A. Biochem. biophys. Res. Commun. 192 , 1303–1311 (1993).Article CAS PubMed Google Scholar
Van Horn, D. J., Myers, M. G. Jr & Backer, J. M. J. Biochem. 269 , 29–32 (1994).CAS Google Scholar
Waters, S. B., Yamauchi, K. & Pessin, J. E. J. biol. Chem. 268 , 22231–22234 (1993).CAS PubMed Google Scholar
Myers, M. G. Jr. et al. Endocrinology 132 , 1421–1430 (1993).Article CAS PubMed Google Scholar
White, M. F. et al. Cell 54 , 641–649 (1988).Article CAS PubMed Google Scholar
Rose, D. W., Saltiel, A. R., Majumdar, M., Decker, S. J. & Olefsky, J. M. Proc. natn. Acad. Sci. U.S.A. 91 , 797–801 (1994).Article ADS CAS Google Scholar
Tamemoto, H. et al. Nature 372 , 182–186 (1994).Article ADS CAS PubMed Google Scholar
Liu, J. P., Baker, J., Perkins, J. A., Robertson, E. J. & Efstratiadis, A. Cell 75 , 59–72 (1993).CAS PubMed Google Scholar
Miralpeix, M. et al. Biochemistry 31 , 9031–9039 (1992).Article CAS PubMed Google Scholar
Wang, L.-M. et al. Proc. natn. Acad. Sci. U.S.A. 90 , 4032–4036 (1993).Article ADS CAS Google Scholar
Keegan, A. D. et al. Cell 76 , 811–820 (1994).Article CAS PubMed Google Scholar
Wang, L. M. et al. Science 261 , 1591–1594 (1993).Article ADS CAS PubMed Google Scholar
Papaioannou, V. & Johnson, R. in Gene Targeting: A Practical Approach (ed. Joyner, A.) Oxford University Press. Oxford, 1993). Google Scholar
Lipes, M. A. et al. Science 259 , 1165–1169 (1993).Article ADS CAS PubMed Google Scholar
Shepherd, P. R. et al. J. biol. Chem. 269 , 22232–22248 (1993). Google Scholar
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