Neurite growth inhibitors restrict plasticity and functional recovery following corticospinal tract lesions (original) (raw)

• Schwab, M.E. Bartholdi, D. Degeneration and regeneration of axons in the lesioned spinal cord. Physiol. Rev. 76, 319–370 (1996).
  Article CAS Google Scholar
• Schnell, L. Schwab, M.E. Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors . Nature 343, 269–272 (1990).
  Article CAS Google Scholar
• Schnell, L. Schwab, M.E. Sprouting and regeneration of lesioned corticospinal tract fibres in the adult rat spinal cord. Eur. J. Neurosci. 5, 1156–1171 ( 1993).
  Article CAS Google Scholar
• Bregman, B.S. et al. Recovery from spinal cord injury mediated by antibodies to neurite growth inhibitors. Nature 378, 498– 501 (1995).
  Article CAS Google Scholar
• Whishaw, I.Q. Kolb, B. Sparing of skilled forelimb reaching and corticospinal projections after neonatal motor cortex removal or hemidecortication in the rat: support for the Kennard doctrine. Brain Res. 451, 97–114 (1988).
  Article CAS Google Scholar
• Reh, T. Kalil, K. Functional role of regrowing pyramidal tract fibers . J. Comp. Neurol. 211, 276– 283 (1982).
  Article CAS Google Scholar
• Barth, T.M. Stanfield, B.B. The recovery of forelimb-placing behavior in rats with neonatal unilateral cortical damage involves the remaining hemisphere . J. Neurosci. 10, 3449– 3459 (1990).
  Article CAS Google Scholar
• Kennard, M.A. Age and other factors in motor recovery from precentral lesions in monkeys. Am. J. Physiol. 115, 138–146 (1936).
  Article Google Scholar
• Farmer, S.F. Harrison, L.M. Ingram, D.A. Stephens, J.A. Plasticity of central motor pathways in children with hemiplegic cerebral palsy. Neurology 41, 1505–1510 (1991).
  Article CAS Google Scholar
• Carr, L.J. Harrison, L.M. Evans, A.L. Stephens, J.A. Patterns of central motor reorganization in hemiplegic cerebral palsy. Brain 116, 1223–1247 (1993).
  Article Google Scholar
• Kalil, K. Reh, T. Regrowth of severed axons in the neonatal central nervous system: establishment of normal connections. Science 205, 1158–1161 (1979).
  Article CAS Google Scholar
• Kuang, R.Z. Kalil, K. Specificity of corticospinal axon arbors sprouting into denervated contralateral spinal cord. J. Comp. Neurol. 302, 461–472 ( 1990).
  Article CAS Google Scholar
• Kapfhammer, J.P. Schwab, M.E. Inverse patterns of myelination and GAP-43 expression in the adult CNS: neurite growth inhibitors as regulators of neuronal plasticity? J. Comp. Neurol. 340, 194–206 (1994).
  Article CAS Google Scholar
• Vanek, P. Thallmair, M. Schwab, M.E. Kapfhammer, J.P. Increased lesion-induced sprouting in the myelin-free rat spinal cord. Eur. J. Neurosci. 10, 45–56 (1998).
  Article CAS Google Scholar
• Hicks, S.P. D'Amato, C.J. Motor-sensory and visual behavior after hemispherectomy in newborn and mature rats. Exp. Neurol. 29, 416–438 (1970).
  Article CAS Google Scholar
• Kalil, K. Reh, T. A light and electron microscopic study of regrowing pyramidal tract fibers. J. Comp. Neurol. 211, 265–275 (1982).
  Article CAS Google Scholar
• Valverde, F. The pyramidal tract in rodents. A study of its relations with the posterior column nuclei, dorsolateral reticular formation of the medulla oblongata, and cervical spinal cord (Golgi and electron microsopic observations). J. Zellforsch. 71, 297–363 ( 1966).
  Article Google Scholar
• Casale, E.J. Light, A.R. Rustioni, A. Direct projection of the corticospinal tract to the superficial laminae of the spinal cord in the rat. J. Comp. Neurol. 278, 275–286 (1988).
  Article CAS Google Scholar
• Kuang, R.Z. Kalil, K. Branching patterns of corticospinal axon arbors in the rodent. J. Comp. Neurol. 292, 585–598 (1990).
  Article CAS Google Scholar
• Liang, F.Y. Moret, V. Wiesendanger, M. Rouiller, E.M. Corticomotoneuronal connections in the rat: evidence from double-labeling of motoneurons and corticospinal axon arborizations. J. Comp. Neurol. 311, 356–366 (1991).
  Article CAS Google Scholar
• Brösamle, C. Schwab, M.E. Cells Of Origin, Course, and Termination Patterns Of the Ventral, Uncrossed Component Of the Mature Rat Corticospinal Tract. J. Comp. Neurol. 386, 293– 303 (1997).
  Article Google Scholar
• Flumerfelt, B.A. An ultrastructural investigation of afferent connections of the red nucleus in the rat. J. Anat. 131, 621–633 ( 1980).
  CAS PubMed PubMed Central Google Scholar
• Naus, C.G. Flumerfelt, B.A. Hrycyshyn, A.W. An HRP-TMB ultrastructural study of rubral afferents in the rat. J. Comp. Neurol. 239, 453–465 (1985).
  Article CAS Google Scholar
• Mihailoff, G.A. Burne, R.A. Woodward, D.J. Projections of the sensorimotor cortex to the basilar pontine nuclei in the rat: an autoradiographic study. Brain Res. 145, 347–354 ( 1978).
  Article CAS Google Scholar
• Wiesendanger, R. Wiesendanger, M. The corticopontine system in the rat. II. The projection pattern. J. Comp. Neurol. 208, 227–238 (1982).
  Article CAS Google Scholar
• Rouiller, E.M. Moret, V. Liang, F. Comparison of the connectional properties of the two forelimb areas of the rat sensorimotor cortex: support for the presence of a premotor or supplementary motor cortical area. Somatosens. Mot. Res. 10, 269–289 (1993).
  Article CAS Google Scholar
• Panto, M.R. Cicirata, F. Angaut, P. Parenti, R. Serapide, F. The projection from the primary motor and somatic sensory cortex to the basilar pontine nuclei. A detailed electrophysiological and anatomical study in the rat. J. Hirnforsch. 36, 7– 19 (1995).
  CAS PubMed Google Scholar
• Whishaw, I.Q. Pellis, S.M. Gorny, B. Kolb, B. Tetzlaff, W. Proximal and distal impairments in rat forelimb use in reaching follow unilateral pyramidal tract lesion. Behav. Brain Res. 56, 59–76 (1993).
  Article CAS Google Scholar
• Spillmann, A.A. Amberger, V.R. Schwab, M.E. High molecular weight protein of human central nervous system myelin inhibits neuriite outgrowth: An effect which can be neutralized by the monoclonal antibody IN-1. Eur. J. Neurosci. 9, 549–555 (1997).
  Article CAS Google Scholar
• Rubin, B.P. Dusart, I. Schwab, M.E. A monoclonal antibody (IN-1) which neutralizes neurite growth inhibitory proteins in the rat CNS recognizes antigens localized in CNS myelin. J. Neurocytol. 23, 209–217 (1994).
  Article CAS Google Scholar
• Rouiller, E.M. Liang, F.Y. Moret, V. Wiesendanger, M. Trajectory of redirected corticospinal axons after unilateral lesion of the sensorimotor cortex in neonatal rat; a phaseolus vulgaris-leucoagglutinin (PHA-L) tracing study. Exp. Neurol. 114, 53–65 ( 1991).
  Article CAS Google Scholar
• Bandtlow, C. Schiweck, W. Tai, H.H. Schwab, M.E. Skerra, A. The Escherichia coli-derived Fab fragment of the IgM/kappa antibody IN-1 recognizes and neutralizes myelin-associated inhibitors of neurite growth. Eur. J. Biochem. 241, 468–475 (1996).
  Article CAS Google Scholar
• Akintunde, A. Buxton, D.F. Origins and collateralization of corticospinal, corticopontine, corticorubral and corticostriatal tracts: a multiple retrograde fluorescent tracing study. Brain Res. 586, 208–218 (1992).
  Article CAS Google Scholar
• Antal, M. Termination areas of corticobulbar and corticospinal fibres in the rat. J. Hirnforsch. 25, 647–659 ( 1984).
  CAS PubMed Google Scholar
• Castro, A.J. Motor performance in rats. The effects of pyramidal tract section. Brain Res. 44, 313–23 (1972).
  Article CAS Google Scholar
• Caroni, P. Schwab, M.E. Antibody against myelin-associated inhibitor of neurite growth neutralizes nonpermissive substrate properties of CNS white matter. Neuron 1, 85–96 (1988).
  Article CAS Google Scholar
• Leong, S.K. Lund, R.D. Anomalous bilateral corticofugal pathways in albino rats after neonatal lesions. Brain Res. 62 , 218–221 (1973).
  Article CAS Google Scholar
• Naus, C.G. Flumerfelt, B.A. Hrycyshyn, A.W. An anterograde HRP-WGA study of aberrant corticorubral projections following neonatal lesions of rat sensorimotor cortex. Exp. Brain Res. 59, 365–371 (1985).
  Article CAS Google Scholar
• Castro, A.J. Mihailoff, G.A. Corticopontine remodelling after cortical and/or cerebellar lesions in newborn rats. J. Comp. Neurol. 219, 112–123 (1983).
  Article CAS Google Scholar
• Fagan, A.M. et al. Endogenous FGF-2 is important for cholinergic sprouting in the denervated hippocampus. J. Neurosci. 17, 2499– 2511 (1997).
  Article CAS Google Scholar
• Thoenen, H. Neurotrophins and neuronal plasticity. Science 270, 593 –598 (1995).
  Article CAS Google Scholar
• Kalil, K. Schneider, G.E. Motor performance following unilateral pyramidal tract lesions in the hamster. Brain Res. 100, 170–174 (1975).
  Article CAS Google Scholar
• Castro, A.J. The effects of cortical ablations on digital usage in the rat. Brain Res. 37, 173–85 (1972).
  Article CAS Google Scholar
• Endo, K. Araki, T. Yagi, N. The distribution and pattern of axon branching of pyramidal tract cells. Brain Res. 57, 484–491 ( 1973).
  Article CAS Google Scholar
• Cao, Y. Vikingstad, E.M. Huttenlocher, P.R. Towle, V.L. Levin, D.N. Functional magnetic resonance studies of the reorganization of the human hand sensorimotor area after unilateral brain injury in the perinatal period. Proc. Natl Acad. Sci.U.S.A. 91, 9612–9616 ( 1994).
  Article CAS Google Scholar
• Herzog, A. Brösamle, C. Semifree-floating treatment - a simple and fast method to process consecutive sections for immunohistochemistry and neuronal tracing. J. Neurosci. Methods 72, 57–63 (1997).
  Article CAS Google Scholar
• Kartje-Tillotson, G. Castro, A.J. Limb preference after unilateral pyramidotomy in adult and neonatal rats. Physiol. Behav. 24, 293–296 (1980).
  Article CAS Google Scholar
• Carlini, E.A. Teresa, M. Silva, A. Cesare, L.C. Endo, R.M. Effects of administration of B-(3,4-dimethoxyphenyl)-ethylamine and B-(3,4,5-trimethoxyphenyl)-ethylamine on the climbing rope performance of rats. Med. Pharmacol. Exp. 17, 534–542 ( 1967).
  CAS Google Scholar
• Hernandez, T.D. Schallert, T. Seizures and recovery from experimental brain damage. Exp. Neurol. 102, 318– 324 (1988).
  Article CAS Google Scholar
• de Medinaceli, L. Freed, W.J. Wyatt, R.J. An index of the functional condition of rat sciatic nerve based on measurements made from walking tracks. Exp. Neurol. 77, 634–643 (1982).
  Article CAS Google Scholar