Effect of high salt concentrations on water structure (original) (raw)

Nature volume 378, pages 364–366 (1995) Cite this article

Abstract

THE characteristic tetrahedral structure of water is known to be disrupted by changes in pressure and temperature1–3. It has been suggested that ions in solution may have a similar perturbing effect4,5. Here we use neutron diffraction to compare the effects of applied pressure and high salt concentrations on the hydrogen-bonded network of water. We find that the ions induce a change in structure equivalent to the application of high pressures, and that the size of the effect is ion-specific. Ionic concentrations of a few moles per litre have equivalent pressures that can exceed a thousand atmospheres. We propose that these changes may be understood in terms of the partial molar volume of the ions, relative to those of water molecules. The equivalent induced pressure of a particular ion species is correlated with its efficacy in precipitating, or salting-out, proteins from solution6.

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References

  1. Postorino, P., Tromp, R. H., Ricci, M.-A., Soper, A. K. & Nielson, G. W. Nature 366, 668–670 (1993).
    Article ADS CAS Google Scholar
  2. Postorino, P., Ricci, M. A. & Soper, A. K. J. chem. Phys. 101, 4123–4132 (1994).
    Article ADS CAS Google Scholar
  3. Tromp, R. H., Posterino, P., Neilson, G. W., Ricci, M. A. & Soper, A. K. J. chem. Phys. 101, 6210–6215 (1994).
    Article ADS CAS Google Scholar
  4. Tromp, R. H., Neilson, G. W. & Soper, A. K. J. chem. Phys. 96, 8460–8469 (1992).
    Article ADS CAS Google Scholar
  5. Enderby, J. E., Howells, W. S. & Howe, R. A. Chem. Phys. Lett. 21, 109–112 (1973).
    Article ADS CAS Google Scholar
  6. Hofmeister, F. Arch. Exp. Path. Pharmakol. 24, 247–260 (1888).
    Article Google Scholar
  7. Zubay, G. Biochemistry 3rd Edn (Brown, Dubuque, IA, 1993).
    Google Scholar
  8. Herdman, G. J. & Neilson, G. W. J. Molec. Liq. 46, 165–179 (1990).
    Article CAS Google Scholar
  9. Soper, A. K., Howells, W. S. & Hannon, A. C. ATLAS: Analysis of Time-of-flight Diffraction Data from Liquid and Amorphous Samples (Rep. No. 89-046, Rutherford Appleton Lab., Chilton, 1989).
    Google Scholar
  10. Soper, A. K. & Luzar, A. J. chem. Phys. 97, 1320–1331 (1993).
    Article ADS Google Scholar
  11. Soper, A. K. & Tumer, J. Z. Int. J. mod. Phys. 7, 3049–3076 (1993).
    Article ADS CAS Google Scholar
  12. Soper, A. K. & Phillips, M. C. Chem. Phys. 107, 47–60 (1993).
    Article Google Scholar
  13. Millero, F. J. Chem. Rev. 72, 147–176 (1971).
    Article Google Scholar
  14. Handbook of Chemistry and Physics 55th Edn D194–D236 (CRC, Cleveland, 1974).

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Authors and Affiliations

  1. European Molecular Biology Laboratory, Grenoble Outstation, BP 156, 38042, Grenoble Cedex, France
    R. Leberman
  2. ISIS Facility, Rutherford Appleton Laboratory, Chilton, Didcot, Oxfordshire, 0X11 OQX, UK
    A. K. Soper

Authors

  1. R. Leberman
  2. A. K. Soper

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Leberman, R., Soper, A. Effect of high salt concentrations on water structure.Nature 378, 364–366 (1995). https://doi.org/10.1038/378364a0

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