Evolution of genetic redundancy (original) (raw)

• Brookfield, J. F. Y. Genetic redundancy. Adv. Genet. 36, 137–155 (1997).
  Article CAS Google Scholar
• Brookfield, J. F. Y. Can genes be truly redundant? Curr. Biol. 2, 553–554 (1992).
  Article CAS Google Scholar
• Tautz, D. Redundancies, development and the flow of information. BioEssays 14, 263–266 (1992).
  Article CAS Google Scholar
• Goldstein, D. B. & Holsinger, K. E. Maintenance of polygenic variation in spatially structured populations. Evolution 46, 412–429 (1992).
  Article Google Scholar
• Thomas, J. H. Thinking about genetic redundancy. Trends Genet. 9, 395–399 (1993).
  Article CAS Google Scholar
• Dover, G. A. Evolution of genetic redundancy for advanced players. Curr. Opin. Genet. Dev. 3, 902–910 (1993).
  Article CAS Google Scholar
• Pickett, F. B. & Meeks-Wagner, D. R. Seeing double: appreciating genetic redundancy. Plant Cell 7, 1347–1356 (1995).
  Article CAS Google Scholar
• Bird, A. P. Gene number, noise reduction and biological complexity. Trends Genet. 11, 94–100 (1995).
  Article CAS Google Scholar
• O'Brien, S. J. On estimating function gene number in eukaryotes. Nature New Biol. 242, 52–54 (1973).
  Article CAS Google Scholar
• Kastner, P. et al. Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life? Cell 83, 859–869 (1995).
  Article CAS Google Scholar
• Rudnicki, M. A. et al. Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development. Cell 71, 383–390 (1992).
  Article CAS Google Scholar
• Saga, Y. et al. Mice develop normally without tenascin. Genes Dev. 6, 1821–1831 (1992).
  Article CAS Google Scholar
• Yang, Y. et al. Functional redundancy of the muscle-specific transcription factors Myf5 and myogenin. Nature 379, 823–825 (1996).
  Article ADS Google Scholar
• Joyner, A. L. et al. Subtle cerebellar phenotype in mice homozygous for a targeted deletion of the En-2 homeobox. Science 251, 1239–1243 (1991).
  Article ADS CAS Google Scholar
• Laney, J. D. & Biggin, M. D. Redundant control of Ultrabithorax by zeste involves functional levels of zeste protein binding at the Ultrabithorax promoter. Development 122, 2303–2311 (1996).
  CAS PubMed Google Scholar
• Schorle, H. et al. Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting. Nature 352, 621–624 (1991).
  Article ADS CAS Google Scholar
• Taniguchi, T. Cytokine signaling through nonreceptor protein tyrosine kinases. Science 268, 251–255 (1995).
  Article ADS CAS Google Scholar
• Steindler, D. A. et al. Tenascin Knockout Mice: Barrels, Boundary Molecules, and Glial Scars. J. Neurosci. 15, 1971–1983 (1995).
  Article CAS Google Scholar
• Pekny, M. et al. Mice lacking glial fibrallary acidic protein display astrocytes devoid of intermediate filaments but develop and reproduce normally. EMBO J. 14, 1590–1598 (1995).
  Article CAS Google Scholar
• Reed, S. I. G1-specific cyclins in search of an S-phase promoting factor. Trends Genet. 7, 95–99 (1991).
  Article CAS Google Scholar
• Roche, S. et al. Requirement for Src family protein tyrosine kinases in G-2 for fibroblast cell division. Science 269, 1567–1569 (1995).
  Article ADS CAS Google Scholar
• Fisher, R. A. The sheltering of lethals. Am. Nat. 69, 446–455 (1935).
  Article Google Scholar
• Christiansen, F. B. & Frydenberg, O. Selection-mutation balance for two nonallelic recessives producing an inferior double homozygote. Am. J. Hum. Genet. 29, 195–207 (1977).
  CAS PubMed PubMed Central Google Scholar
• Bailey, G. S. et al. Gene duplication in tetraploid fish: model for gene silencing at unlinked loci. Proc. Natl Acad. Sci. USA 75, 5575–5579 (1978).
  Article ADS CAS Google Scholar
• Allendorf, F. W. Protein polymorphism and the rate of loss of duplicate gene expression. Nature 272, 76–78 (1978).
  Article ADS CAS Google Scholar
• Kimura, M. & King, J. L. Fixation of a deleterious allele at one of two duplicate loci by mutation pressure and random drift. Proc. Natl Acad. Sci. USA 76, 2858–2861 (1979).
  Article ADS CAS Google Scholar
• Li, W.-H. Rate of gene silencing at duplicate loci: a theoretical study and interpretation of data from tetraploid fish. Genetics 95, 237–258 (1980).
  CAS PubMed PubMed Central Google Scholar
• Ohta, T. Time for spreading of compensatory mutations under gene duplication. Genetics 123, 579–584 (1989).
  CAS PubMed PubMed Central Google Scholar
• Li, X. & Noll, M. Evolution of distinct developmental functions of three Drosophila genes by acquisition of different _cis_-regulatory regions. Nature 367, 83–87 (1994).
  Article ADS CAS Google Scholar
• Krakauer, D. C. & Pagel, M. Selection by somatic signals. Phil. Trans. R. Soc. Lond. B 351, 647–658 (1996).
  Article ADS CAS Google Scholar