Structural biology and phylogenetic estimation (original) (raw)

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• Published: 07 August 1997

Nature volume 388, pages 527–528 (1997)Cite this article

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Abstract

When reconstructing evolutionary trees from DNA sequences, it is often assumed that increasing the amount of sequence will improve the phylogenetic estimate1,2. This is based on the notion that historical ‘signal’ will rise above misleading ‘noise’ as more sequence is gathered. Our analysis of mitochondrial genomes fails to support this assumption, but suggests a way to select objectively for data with maximum ‘signal-to-noise’ potential.

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Authors and Affiliations

1. Department of Zoology and Genetics, Iowa State University, Ames, 50011, Iowa, USA
   Gavin J. P. Naylor
2. Department of Biology, University of Michigan, Ann Arbor, 48109-1048, Michigan, USA
   Wesley M. Brown

Authors

1. Gavin J. P. Naylor
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2. Wesley M. Brown
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Naylor, G., Brown, W. Structural biology and phylogenetic estimation.Nature 388, 527–528 (1997). https://doi.org/10.1038/41460

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• Issue Date: 07 August 1997
• DOI: https://doi.org/10.1038/41460

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