Different lateral amygdala outputs mediate reactions and actions elicited by a fear-arousing stimulus (original) (raw)

References

  1. Blanchard, R. J. & Blanchard, D. C. Defensive reactions in the albino rat. Learn. Motivat. 2, 351–362 (1971).
    Article Google Scholar
  2. Bolles, R. C. Reinforcement, expectancy, and learning. Psychol. Rev. 79, 394–409 (1972).
    Article Google Scholar
  3. McAllister, W. R. & McAllister, D. E. in Aversive Conditioning and Learning (ed. Brush, F. R.) 105– 179 (Academic, New York, 1971).
    Book Google Scholar
  4. Miller, N. E. Studies of fear as an acquirable drive: I. Fear as motivation and fear reduction as reinforcement in the learning of new responses. J. Exp. Psychol. 38, 89–101 ( 1948).
    Article CAS Google Scholar
  5. LeDoux, J. E. Emotion circuits in the brain. Annu. Rev. Neurosci. 23 155–184 (2000).
  6. Davis, M. The role of the amygdala in emotional learning. Int. Rev. Neurobiol. 36, 225–266 ( 1994).
    Article CAS Google Scholar
  7. Maren, S. & Fanselow, M. S. The amygdala and fear conditioning: has the nut been cracked? Neuron 16, 237 –240 (1996).
    Article CAS Google Scholar
  8. LeDoux, J. E., Cicchetti, P., Xagoraris, A. & Romanski, L. M. The lateral amygdaloid nucleus: Sensory interface of the amygdala in fear conditioning. J. Neurosci. 10, 1062– 1069 (1990).
    Article CAS Google Scholar
  9. LeDoux, J. E., Iwata, J., Cicchetti, P. & Reis, D. J. Different projections of the central amygdaloid nucleus mediate autonomic and behavioral correlates of conditioned fear. J. Neurosci. 8, 2517 –2529 (1988).
    Article CAS Google Scholar
  10. Walker, D. L. & Davis, M. Double dissociation between the involvement of the bed nucleus of the stria terminalis and the central nucleus of the amygdala in startle increases produced by conditioned versus unconditioned fear. J. Neurosci. 17, 9375– 9383 (1997).
    Article CAS Google Scholar
  11. Campeau, S. & Davis, M. Involvement of the central nucleus and basolateral complex of the amygdala in fear conditioning measured with fear-potentiated startle in rats trained concurrently with auditory and visual conditioned stimuli. J. Neurosci. 15, 2301 –2311 (1995).
    Article CAS Google Scholar
  12. Roozendaal, B., Koolhaas, J. M. & Bohus, B. Central amygdala lesions affect behavioral and autonomic balance during stress in rats. Physiol. Behav. 50, 777–781 (1991).
    Article CAS Google Scholar
  13. Kapp, B. S., Frysinger, R. C., Gallagher, M. & Haselton, J. Amygdala central nucleus lesions: effect on heart rate conditioning in the rabbit. Physiol. Behav. 23, 1109– 1117 (1979).
    Article CAS Google Scholar
  14. Everitt, B. J. & Robbins, T. W. in The Amygdala: Neurobiological Aspects of Emotion, Memory and Mental Dysfunction (ed. Aggleton, J. P.) 401–430 (Wiley, New York, 1992).
    Google Scholar
  15. Killcross, S., Robbins, T. W. & Everitt, B. J. Different types of fear-conditioned behavior mediated by separate nuclei within amygdala. Nature 388, 377–380 (1997).
    Article CAS Google Scholar
  16. Pitkänen, A., Savander, V. & LeDoux, J. L. Organization of intra-amygdaloid circuitries: an emerging framework for understanding functions of the amygdala. Trends Neurosci. 20, 517–523 (1997).
    Article Google Scholar
  17. Amaral, D. G., Price, J. L., Pitkänen, A. & Carmichael, S. T. in The Amygdala: Neurobiological Aspects of Emotion, Memory, and Mental Dysfunction (ed. Aggleton, J. P.) 1–66 (Wiley-Liss, New York, 1992).
    Google Scholar
  18. McDonald, A. J. Cortical pathways to the mammalian amygdala. Prog. Neurobiol. 55, 257–332 (1998).
    Article CAS Google Scholar
  19. Turner, B. & Herkenham, M. Thalamoamygdaloid projections in the rat: a test of the amygdala's role in sensory processing. J. Comp. Neurol. 313, 295–325 (1991).
    Article CAS Google Scholar
  20. Mascagni, F., McDonald, A. J. & Coleman, J. R. Corticoamygdaloid and corticocortical projections of the rat temporal cortex: a phaseolus vulgaris leucoagglutinin study. Neuroscience 57, 697–715 (1993).
    Article CAS Google Scholar
  21. Romanski, L. M., LeDoux, J. E., Clugnet, M. C. & Bordi, F. Somatosensory and auditory convergence in the lateral nucleus of the amygdala. Behav. Neurosci. 107, 444– 450 (1993).
    Article CAS Google Scholar
  22. Helmstetter, F. The amygdala is essential for the expression of conditioned hypoalgesia. Behav. Neurosci. 106, 518–528 (1992).
    Article CAS Google Scholar
  23. Mackintosh, N. J. Conditioning and Associative Learning (eds. Broadbent, D. E. et al. ) (Oxford Univ. Press, New York, 1983).
    Google Scholar
  24. Hatfield, T., Han, J.-S., Conley, M., Gallagher, M. & Holland, P. Neurotoxic lesions of basolateral, but not central, amygdala interfere with Pavlovian second-order conditioning and reinforcer devaluation effects. J. Neurosci. 16, 5256 –5265 (1996).
    Article CAS Google Scholar
  25. Robbins, T. W., Cador, M., Taylor, J. R. & Everitt, B. J. Limbic-striatal interactions in reward-related processes. Neurosci. Biobehav. Rev. 13, 155–162 ( 1989).
    Article CAS Google Scholar
  26. Paré, D., Smith, Y. & Pare, J. F. Intra-amygdaloid projections of the basolateral and basomedial nuclei in the cat: phaseolus vulgaris-leucoagglutinin anterograde tracing at the light and electron microscopic level. Neuroscience 69, 567–583 (1995).
    Article Google Scholar
  27. Maren, S. Overtraining does not mitigate contextual fear conditioning deficits produced by neurotoxic lesions of the basolateral amygdala. J. Neurosci. 18, 3088–3097 ( 1998).
    Article CAS Google Scholar
  28. Bolles, R. C. & Fanselow, M. S. A perceptual-defensive-recuperative model of fear and pain. Behav. Brain Sci. 3, 291–323 (1980).
    Article Google Scholar
  29. Fanselow, M. S. Conditional and unconditional components of post-shock freezing. Pavl. J. Biol. Sci. 15, 177–182 (1980).
    CAS Google Scholar
  30. Fanselow, M. S. & Lester, L. S. in Evolution and Learning (eds. Bolles, R. C. & Beecher, M. D.) 185– 211 (Erlbaum, Hillsdale, New Jersey, 1987).
    Google Scholar
  31. Nader, K. & LeDoux, J. E. Is it time in invoke multiple fear learning system? Trends Cog. Sci. 1, 241–244 (1997).
    Article CAS Google Scholar
  32. Killcross, A. S., Robbins, T. W. & Everitt, B. J. Response from Killcross, Robbins and Everitt. Trends Cog. Sci. 1, 244–246 (1997).
    Article CAS Google Scholar
  33. Fanselow, M. S. & LeDoux, J. E. Why we think plasticity underlying Pavlovian fear conditioning occurs in the basolateral amygdala. Neuron 23, 229– 232 (1999).
    Article CAS Google Scholar
  34. Cahill, L., Weinberger, N. M., Roozendaal, B. & McGaugh, J. L. Is the amygdala a locus of "conditioned fear"? Some questions and caveats. Neuron 23, 227–228 (1999).
    Article CAS Google Scholar
  35. Cahill, L. & McGaugh, J. L. Mechanisms of emotional arousal and lasting declarative memory. Trends Neurosci. 21 , 294–299 (1998).
    Article CAS Google Scholar
  36. Mowrer, O. H. & Lamoreaux, R. R. Fear as an intervening variable in avoidance conditioning. J. Comp. Psychol. 39, 29–50 (1946).
    Article CAS Google Scholar
  37. Mowrer, O. H. Learning Theory and Behavior (Wiley, New York, 1960 ).
    Book Google Scholar
  38. Miller, N. E. in Handbook of Experimental Psychology (ed. Stevens, S. S.) 435– 472 (Wiley, New York, 1951).
    Google Scholar

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