Fosl1 is a transcriptional target of c-Fos during osteoclast differentiation (original) (raw)
References
Wang, Z.Q. et al. Bone and haematopoietic defects in mice lacking c-fos. Nature360, 741–745 ( 1992). ArticleCAS Google Scholar
Johnson, R.S., Spiegelman, B.M. & Papaioannou, V. Pleiotropic effects of a null mutation in the c- fos proto-oncogene. Cell71, 577– 586 (1992). ArticleCAS Google Scholar
Grigoriadis, A.E. et al. c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling. Science266, 443– 448 (1994). ArticleCAS Google Scholar
Wisdon, R. & Verma, I.M. Transformation by Fos proteins requires a C-terminal transactivation domain. Mol. Cell. Biol.13, 7429–7438 (1993). ArticleCAS Google Scholar
Jooss, K.U., Funk, M. & Müller, R. An autonomous N-terminal transactivation domain in Fos protein plays a crucial role in transformation. EMBO J.13, 1467–1475 (1994). ArticleCAS Google Scholar
Funk, M., Poensgen, B., Graulich, W., Jerome, V. & Müller, R. A novel, transformation-relevant activation domain in Fos proteins. Mol. Cell. Biol.17, 537–544 (1997). ArticleCAS Google Scholar
Bergers, G., Graninger, P., Braselmann, S., Wrighton, C. & Busslinger, M. Transcriptional activation of the fra-1 gene by AP-1 is mediated by regulatory sequences in the first intron . Mol. Cell. Biol.15, 3748– 3758 (1995). ArticleCAS Google Scholar
Wong, B.R. et al. TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor. J. Exp. Med.186, 2075–2080 (1997). ArticleCAS Google Scholar
Anderson, D.M. et al. A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. Nature390, 175–179 (1997). ArticleCAS Google Scholar
Yasuda, H. et al. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc. Natl Acad. Sci. USA95, 3597–3602 ( 1998). ArticleCAS Google Scholar
Lacey, D.L. et al. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell93, 165–176 (1998). ArticleCAS Google Scholar
Kustikova, O. et al. Fra-1 induces morphological transformation and increases in vitro invasiveness and motility of epithelioid adenocarcinoma cells. Mol. Cell. Biol.18, 7095–7105 (1998). ArticleCAS Google Scholar
Grigoriadis, A.E., Schellander, K., Wang, Z.Q. & Wagner, E.F. Osteoblasts are target cells for transformation in c-fos transgenic mice. J. Cell Biol.122, 685–701 (1993). ArticleCAS Google Scholar
Sutherland, J.A., Cook, A., Bannister, A.J. & Kouzarides, T. Conserved motifs in Fos and Jun define a new class of activation domain. Genes Dev.6, 1810–1819 (1992). ArticleCAS Google Scholar
Metz, R. et al. c-Fos-induced activation of a TATA-box-containing promoter involves direct contact with TATA-box-binding protein. Mol. Cell. Biol.14, 6021–6029 ( 1994). ArticleCAS Google Scholar
Metz, R., Kouzarides, T. & Bravo, R. A C-terminal domain in FosB, absent in FosB/SF and Fra-1, which is able to interact with the TATA binding protein, is required for altered cell growth. EMBO J.13, 3832– 3842 (1994). ArticleCAS Google Scholar
Wisdom, R., Yen, J., Rashid, D. & Verma, I.M. Transformation by FosB requires a trans-activation domain missing in FosB2 that can be substituted by heterologous activation domains. Genes Dev.6, 667–675 (1992). ArticleCAS Google Scholar
Oliviero, S., Robinson, G.S., Struhl, K. & Spiegelman, B.M. Yeast GCN4 as a probe for oncogenesis by AP-1 transcription factors: transcriptional activation through AP-1 sites is not sufficient for cellular transformation . Genes Dev.6, 1799–1809 (1992). ArticleCAS Google Scholar
Wrighton, C. & Busslinger, M. Direct transcriptional stimulation of the ornithine decarboxylase gene by Fos in PC12 cells but not in fibroblasts . Mol. Cell. Biol.13, 4657– 4669 (1993). ArticleCAS Google Scholar
Owens, J.M., Matsuo, K., Nicholson, G.C., Wagner, E.F. & Chambers, T.J. Fra-1 potentiates osteoclastic differentiation in osteoclast-macrophage precursor cell lines. J. Cell. Physiol.179, 170–178 (1999). ArticleCAS Google Scholar
Hsu, H. et al. Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand. Proc. Natl Acad. Sci. USA96, 3540– 3545 (1999). ArticleCAS Google Scholar
Russell, R.G.G. & Rogers, M.J. Bisphosphonates: from the laboratory to the clinic and back again. Bone25, 97–106 (1999). ArticleCAS Google Scholar
Schreiber, M. et al. Structure and chromosomal assignment of the mouse fra-1 gene, and its exclusion as a candidate gene for oc (osteosclerosis). Oncogene15, 1171–1178 ( 1997). ArticleCAS Google Scholar
Kong, Y.Y. et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature397 , 315–323 (1999). ArticleCAS Google Scholar
Dougall, W.C. et al. RANK is essential for osteoclast and lymph node development . Genes Dev.13, 2412–2424 (1999). ArticleCAS Google Scholar
Morgenstern, J.P. & Land, H. Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res.18, 3587–3596 (1990). ArticleCAS Google Scholar
Chambers, T.J., Owens, J.M., Hattersley, G., Jat, P.S. & Noble, M.D. Generation of osteoclast-inductive and osteoclastogenic cell lines from the H-2KbtsA58 transgenic mouse. Proc. Natl Acad. Sci. USA90, 5578– 5582 (1993). ArticleCAS Google Scholar
Livak, K.J., Flood, S.J., Marmaro, J., Giusti, W. & Deetz, K. Oligonucleotides with fluorescent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridization. PCR Methods Appl.4, 357–362 (1995). ArticleCAS Google Scholar
Brown, H.J., Sutherland, J.A., Cook, A., Bannister, A.J. & Kouzarides, T. An inhibitor domain in c-Fos regulates activation domains containing the HOB1 motif. EMBO J.14, 124–131 ( 1995). ArticleCAS Google Scholar
Gius, D. et al. Transcriptional activation and repression by Fos are independent functions: the C terminus represses immediate-early gene expression via CArG elements. Mol. Cell. Biol.10, 4243– 4255 (1990). ArticleCAS Google Scholar