AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1 (original) (raw)

• Tsuda, M. et al. The cell-surface proteoglycan Dally regulates Wingless signalling in Drosophila. Nature 400, 276– 280 (1999).
  Article CAS Google Scholar
• Itoh, K., Krupnik, V.E. & Sokol, S.Y. Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and β-catenin. Curr. Biol. 8, 591–594 ( 1998).
  Article CAS Google Scholar
• Lee, Y.J., Swencki, B., Shoichet, S. & Shivdasani, R.A. A possible role for the high mobility group box transcription factor TCF4 in vertebrate gut epithelial cell differentiation. J. Biol. Chem. 274, 1566–1572 ( 1999).
  Article CAS Google Scholar
• Morin, P.J. et al. Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC. Science 275, 1787–1790 (1997).
  Article CAS Google Scholar
• He, T.C. et al. Identification of c-MYC as a target of the APC pathway. Science. 281, 1509–1512 (1998).
  Article CAS Google Scholar
• Tetsu, O. & McCormick, F. β-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 398, 422–426 (1999).
  Article CAS Google Scholar
• Fukuchi, T. et al. β-catenin mutation in carcinoma of the uterine endometrium . Cancer Res. 58, 3526– 3528 (1998).
  CAS PubMed Google Scholar
• Chan, E.F., Gat, U., McNiff, J.M. & Fuchs, E. A common human skin tumour is caused by activating mutations in β-catenin. Nature Genet. 21, 410–413 ( 1999).
  Article CAS Google Scholar
• Miyoshi, Y. et al. Activation of the β-catenin gene in primary hepatocellular carcinomas by somatic alterations involving exon 3. Cancer Res. 58, 2524–2527 ( 1998).
  CAS PubMed Google Scholar
• Voeller, H.J., Truica, C.I. & Gelmann, E.P. β-catenin mutations in human prostate cancer . Cancer Res. 58, 2520– 2523 (1998).
  CAS PubMed Google Scholar
• Zurawel, R.H., Chiappa, S.A., Allen, C. & Raffel, C. Sporadic medulloblastomas contain oncogenic β-catenin mutations. Cancer Res. 58, 896–899 (1998).
  CAS PubMed Google Scholar
• Iwao, K. et al. Activation of the β-catenin gene by interstitial deletions involving exon 3 in primary colorectal carcinomas without adenomatous polyposis coli mutations. Cancer Res. 58, 1021– 1026 (1998).
  CAS PubMed Google Scholar
• de La Coste, A. et al. Somatic mutations of the β-catenin gene are frequent in mouse and human hepatocellular carcinomas. Proc. Natl Acad. Sci. USA 95, 8847–8851 ( 1998).
  Article CAS Google Scholar
• Ihara, A., Koizumi, H., Hashizume, R. & Uchikoshi, T. Expression of epithelial cadherin and α- and β-catenins in nontumoral livers and hepatocellular carcinomas. Hepatology 23 , 1441–1447 (1996).
  CAS PubMed Google Scholar
• Ding, S.F. et al. The putative tumor suppressor gene on chromosome 5q for hepatocellular carcinoma is distinct from the MCC and APC genes. Cancer Detect. Prev. 17, 405–409 ( 1993).
  CAS PubMed Google Scholar
• Smalley, M.J. et al. Interaction of axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription. EMBO J. 18, 2823–2835 (1999).
  Article CAS Google Scholar
• Hart, M.J., de los Santos, R., Albert, I.N., Rubinfeld, B. & Polakis, P. Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK3β. Curr. Biol. 8, 573– 581 (1998).
  Article CAS Google Scholar
• Nakamura, T. et al. Axin, an inhibitor of the Wnt signalling pathway, interacts with β-catenin, GSK-3β and APC and reduces the β-catenin level . Genes Cells 3, 395–403 (1998).
  Article CAS Google Scholar
• Korinek, V. et al. Constitutive transcriptional activation by a β-catenin-Tcf complex in APC−/− colon carcinoma. Science 275, 1784–1787 (1997).
  Article CAS Google Scholar
• Nakamura, Y. Cleaning up on β-catenin. Nature Med. 3, 499–500 (1997).
  Article CAS Google Scholar
• Orford, K., Orford, C.C. & Byers, S.W. Exogenous expression of β-catenin regulates contact inhibition, anchorage-independent growth, anoikis, and radiation-induced cell cycle arrest. J. Cell Biol. 146, 855– 868 (1999).
  Article CAS Google Scholar
• Zhang, Z. et al. Destabilization of β-catenin by mutations in presenilin-1 potentiates neuronal apoptosis. Nature 395, 698–702 (1998).
  Article CAS Google Scholar
• Morin, P.J., Vogelstein, B. & Kinzler, K.W. Apoptosis and APC in colorectal tumorigenesis. Proc. Natl Acad. Sci. USA 93, 7950– 7954 (1996).
  Article CAS Google Scholar
• Nagai, H. et al. Comprehensive allelotyping of human hepatocellular carcinoma . Oncogene 14, 2927–2933 (1997)
  Article CAS Google Scholar
• Polakis, P. The adenomatous polyposis coli (APC) tumor suppressor. Biochim. Biophys. Acta 1332, F127–F147 (1997).
  CAS Google Scholar
• Takahashi, M. et al. Long term correction of bilirubin-UDP-glucuronosyltransferase deficiency in Gunn rats by administration of a recombinant adenovirus during the neonatal period. J. Biol. Chem. 271, 26536–26542 (1996).
  Article CAS Google Scholar
• McGrory, W.J., Bautista, D.S. & Graham, F.L. A simple technique for the rescue of early region I mutations into infectious human adenovirus type 5. Virology 163, 614–617 (1988).
  Article CAS Google Scholar
• Van de Wetering, M., Castrop, J., Korinek, V. & Clevers, H. Extensive alternative splicing and dual promoter usage generate Tcf-1 protein isoforms with differential transcription control properties. Mol. Cell. Biol. 16, 745–752 (1996).
  Article CAS Google Scholar