Efficient delivery of transgenes to human hair follicle progenitor cells using topical lipoplex (original) (raw)

References

  1. Cotsarelis, G., Sun, T.T. & Lavker, R.M. Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell 61, 1329–1337 (1990).
    Article CAS Google Scholar
  2. Lyle, S. et al. The C8/144B monoclonal antibody recognizes cytokeratin 15 and defines the location of human hair follicle stem cells. J. Cell Sci. 111, 3179–3188 (1998).
    CAS PubMed Google Scholar
  3. Argyris, T. Kinetics of epidermal production during epidermal regeneration following abrasion in mice. Am. J. Pathol. 83, 329–340 (1976).
    CAS PubMed PubMed Central Google Scholar
  4. Paus, R. & Cotsarelis, G. The biology of hair follicles. N. Engl. J. Med. 341, 491–497 (1999).
    Article CAS Google Scholar
  5. Van Scott, E. & Ekel, T. Geometric relationships between the matrix of the hair bulb and its dermal papilla in normal and alopecia scalp. J. Invest. Dermatol. 41, 269–273 (1958).
    Google Scholar
  6. Slominski, A. & Paus, R. Melanogenesis is coupled to murine anagen: toward new concepts for the role of melanocytes and the regulation of melanogenesis in hair growth. J. Invest. Dermatol. 101, 90S–97S (1993).
    Article CAS Google Scholar
  7. Li, L. & Hoffman, R.M. The feasibility of targeted selective gene therapy of the hair follicle. Nat. Med. 1, 705–706 (1995).
    Article Google Scholar
  8. Cotsarelis, G. The hair follicle: dying for attention. Am. J. Pathol. 151, 1505–1509 (1997).
    CAS PubMed PubMed Central Google Scholar
  9. Felgner, P.L. et al. Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proc. Natl. Acad. Sci. USA 84, 7413–7417 (1987).
    Article CAS Google Scholar
  10. Nicolau, C. & Sene, C. Liposome-mediated DNA transfer in eukaryotic cells: dependence of the transfer efficiency on the type of liposome used, and the host cell stage. Biochem. Biophys. Acta 721, 185–190 (1982).
    Article CAS Google Scholar
  11. Wilson, C. et al. Cells within the bulge region of mouse hair follicle transiently proliferate during early anagen: heterogeneity and functional differences of various hair cycles. Differentiation 55, 127–136 (1994).
    Article CAS Google Scholar
  12. Chase, H. Growth of the hair. Physiol. Rev. 34, 113–126 (1954).
    Article CAS Google Scholar
  13. Paus, R., Stenn, R. & Link, R. Telogen skin contains an inhibitor of hair growth. Br. J. Dermatol. 122, 777–784 (1990).
    Article CAS Google Scholar
  14. Alexander, M.Y. & Akhurst, R.J. Liposome-mediated gene transfer and expression via the skin. Hum. Mol. Gen. 4, 2279–2285 (1995).
    Article CAS Google Scholar
  15. Yu, W.H. et al. Topical gene delivery to murine skin. J. Invest. Dermatol. 112, 370–375 (1999).
    Article CAS Google Scholar
  16. Sato, N., Leopold, P.L. & Crystal, R.G. Induction of the hair growth phase in postnatal mice by localized transient expression of Sonic hedgehog. J. Clin. Invest. 104, 855–864 (1999).
    Article CAS Google Scholar
  17. Egilmez, N.K., Iwanuma, Y. & Bankert, R.B. Evaluation and optimization of different cationic liposome formulations for in vivo gene transfer. Biochem. Biophys. Res. Commun. 221, 169–173 (1996).
    Article CAS Google Scholar
  18. Sorgi, F.L., Bhattacharya, S. & Huang, L. Protamine sulfate enhances lipid-mediated gene transfer. Gene Ther. 4, 961–968 (1997).
    Article CAS Google Scholar
  19. Shi, Z., Curiel, D.T. & Tang, D-c. DNA-based non-invasive vaccination onto the skin. Vaccine 17, 2136–2141 (1999).
    Article CAS Google Scholar
  20. Fan, H., Lin, Q., Morrissey, G.R. & Khavari, P.A. Immunization via hair follicles by topical application of naked DNA to normal skin. Nat. Biotechnol. 17, 870–872 (1999).
    Article CAS Google Scholar
  21. Gilhar, A., Ullmann, Y., Berkutzki, T., Assy, B. & Kalish, R.S. Autoimmune hair loss (alopecia areata) transferred by T lymphocytes to human scalp explants on SCID mice. J. Clin. Invest. 101, 62–67 (1998).
    Article CAS Google Scholar
  22. Wrone-Smith, T. & Nickoloff, B.J. Dermal injection of immunocytes induces psoriasis. J. Clin. Invest. 98, 1878–1887 (1996).
    Article CAS Google Scholar
  23. Safavi, K.H., Muller, S.A., Suman, V.J., Moshell, A.N. & Melton, L.J. Incidence of alopecia areata in Olmsted County, Minnesota, 1975 through 1989. Mayo Clin. Proc. 70, 628–633 (1995).
    Article CAS Google Scholar
  24. Van Scott, E.J. Morphologic changes in pilosebaceous units and anagen hairs in alopecia areata. J. Invest. Dermatol. 31, 35–43 (1958).
    Article CAS Google Scholar
  25. Headington, J.T. & Novak, E. Clinical and histologic studies of male pattern baldness treated with topical minoxidil. Curr. Ther. Res. 36, 1098–1106 (1984).
    Google Scholar

Download references