Response of naïve and memory CD8+ T cells to antigen stimulation in vivo (original) (raw)
Owen, J.A., Allouche, M. & Doherty, P.C. Limiting dilution analysis of the specificity of influenza-immune cytotoxic T cells. Cell. Immunol.67, 49–59 (1982). CASPubMed Google Scholar
Ahmed, R. & Gray, D. Immunological memory and protective immunity: understanding their relation. Science272, 54–60 (1996). CASPubMed Google Scholar
Doherty, P.C., Topham, D.J. & Tripp, R.A. Establishment and persistence of virus-specific CD4+ and CD8+ T cells memory. Immunol. Rev.150, 23–44 (1996). CASPubMed Google Scholar
Flynn, K. J. et al. Virus-specific CD8+ T cells in primary and secondary influenza pneumonia. Immunity8, 683–691 (1998). CAS Google Scholar
Murali-Krishna, K. et al. Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection. Immunity8, 177–187 (1998). CASPubMed Google Scholar
Busch, D.H. & Pamer, E.G. T cell affinity maturation by selective expansion during infection. J. Exp. Med.189, 701–10 (1999). CASPubMed Google Scholar
McHeyzer-Williams, L.J., Panus, J.F., Mikszta, J.A. & McHeyzer-Williams, M.G. Evolution of antigen-specific T cell receptors in vivo: preimmune and antigen-driven selection of preferred complementarity-determining region 3 (CDR3) motifs. J. Exp. Med.189, 1823–38 (1999). CASPubMed Google Scholar
Savage, P.A., Boniface, J.J. & Davis, M.M. A kinetic basis for T cell receptor repertoire selection during an immune response. Immunity10, 485–921 (1999). CASPubMed Google Scholar
Selin, L. K. et al. Attrition of T cell memory: Selective loss of LCMV epitope-specific memory CD8 T cells following infections with heterologous viruses. Immunity11, 733–742 (1999). CASPubMed Google Scholar
Budd, R.C. et al. Distinction of virgin and memory T lymphocytes. Stable acquisition of the Pgp-1 glycoprotein concomitant with antigenic stimulation. J. Immunol.138, 3120–3129 (1987). CASPubMed Google Scholar
Bruno, L., Kirberg, J. & von Boehmer, H. On the cellular basis of immunological T cell memory. Immunity2, 37–43 (1995). CASPubMed Google Scholar
Tanchot, C. et al. Differential requirements for survival and proliferation of CD8 naïve or memory T cells. Science276, 2057–2062 (1997). CASPubMed Google Scholar
Curtsinger, J.M., Lins, D.C. & Mescher, M.F. CD8+ memory T cells (CD44high, Ly-6C+) are more sensitive than naive cells (CD44low, Ly-6C-) to TcR/CD8 signaling in response to antigen. J. Immunol.160, 3236–3243 (1998). CASPubMed Google Scholar
Tanchot, C. et al. Modifications of CD8+ T cell function during in vivo memory or tolerance induction. Immunity8, 581–590 (1998). CASPubMed Google Scholar
Cho, B. K. et al. Functional differences between memory and naive CD8 T cells. Proc. Natl Acad. Sci. USA96, 2976–2981 (1999). CASPubMed Google Scholar
Garcia, S., DiSanto, J. & Stockinger, B. Following the Development of a CD4 T cell response in vivo: from activation to memory formation. Immunity11, 163–171 (1999). CAS Google Scholar
Zimmermann, C., Prevost-Blondel, A., Blaser, C. & Pircher, H. Kinetics of the response of naive and memory CD8 T cells to antigen: similarities and differences. Eur. J. Immunol.29, 284–290 (1999). CASPubMed Google Scholar
Bachmann, M.F., Barner, M., Viola, A. & Kopf, M. Distinct kinetics of cytokine production and cytolysis in effector and memory T cells after viral infection. Eur. J. Immunol.29, 291–299 (1999). CASPubMed Google Scholar
Tanchot, C. & Rocha, B. The organization of mature T cell pools. Immunol. Today19, 575–579 (1998). CASPubMed Google Scholar
Shinkai, Y. et al. RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement. Cell68, 855–867 (1992). CAS Google Scholar
Kisielow, P et al. Tolerance in T cell receptor transgenic mice involves deletion of nonmature CD4+CD8+ thymocytes. Nature333, 742–746 (1988). CASPubMed Google Scholar
Rocha, B., Grandien, A. & Freitas, A.A. Anergy and exhaustion are independent mechanisms of peripheral tolerance. J. Exp. Med.181, 993–1003 (1995). CASPubMed Google Scholar
McLean, A. R. et al. Resourse competition as a mechanism for B cell homeostasis. Proc. Natl Acad. Sci. USA94, 5792–5797 (1997). CASPubMed Google Scholar
Borghans, J.A.M., Taams, L.S., Wauben, M.H.M. & De Boer, R. Competition for antigenic sites during T cell proliferation: a mathematical interpretation of in vitro data. Proc. Natl Acad. Sci. USA96, 10782–10787 (1999). CASPubMed Google Scholar
Tripp, R.A., Lahti, J.M. & Doherty, P.C. Laser light suicide of proliferating virus-specific CD8+ T cells in an in vivo response. J. Immunol.155, 3719–3721 (1995). CASPubMed Google Scholar
Sprent, J., Tough, D.F. & Sun, S. Factors controlling the turnover of T memory cells. Immunol. Rev.156, 79–85 (1997). CAS Google Scholar
Leslie, P.H. Some further notes on the use of matrices in population mathematics. Biometrika35, 213–245 (1948). Google Scholar
De Boer, R.J. & Noest, A.J. T cell renewal rates, telomerase and telomere length shortening. J. Immunol.160, 5832–5837 (1998). CASPubMed Google Scholar
Karulin, A.Y., Hesse, M.D., Tary-Lehmann, M. & Lehmann, P.V. Single-cytokine-producing CD4 memory cells predominate in type 1 and type 2 immunity. J. Immunol.164, 1862–1872 (2000). CASPubMed Google Scholar
Valitutti, S. et al. Serial triggering of many T-cell receptors by a few peptide-MHC complexes. Nature11, 148–151 (1995). Google Scholar
Bachmann, M.F. et al. Developmental regulation of Lck targeting to the CD8 coreceptor controls signaling in naive and memory T cells. J. Exp. Med.189, 1521–1529 (1999). CASPubMed Google Scholar
Mackay, C.R. Migration pathways and immunologic memory among T lymphocytes. Semin. Immunol.4, 51–58 (1992). CASPubMed Google Scholar
Brown, K.E. et al. Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division. Mol. Cell.3, 207–217 (1999). CASPubMed Google Scholar
Agarwal, S. & Rao, A. Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation. Immunity9, 765–775 (1998). CASPubMed Google Scholar
Fitzpatrick, D.R., Shirley, K.M. & Kelso, A. Stable epigenetic inheritance of regional IFN-gamma promoter demethylation in CD44 high CD8+ T lymphocytes. J. Immunol.162, 5053–5057 (1999). CASPubMed Google Scholar
Swain, S.L. et al. From naive to memory T cells. Immunol Rev.150, 143–167 (1996). CASPubMed Google Scholar
Gett, A. & Hodgkin, P.D. Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulation. Proc. Natl Acad. Sci. USA95, 9488–9493 (1998). CASPubMed Google Scholar
Bird, J.J. et al. Helper T cell differentiation is controlled by the cell cycle. Immunity9, 229–237 (1998). CASPubMed Google Scholar
Richter, A., Lohning, M. & Radbruch, A. Instruction for cytokine expression in T helper lymphocytes in relation to proliferation and cell progression. J. Exp. Med.190, 1439–1450 (1999). CASPubMed Google Scholar
Gudmundsdottir, H., Wells, A.D. & Turka, L.A. Dynamics and requirements of T cell clonal expansion in vivo at the single-cell level: effector function is linked to proliferative capacity. J. Immunol.162, 5212–5223 (1999). CASPubMed Google Scholar
Sad, S. & Mosmann, T.R. Single IL-2 secreting precursor CD4 T cell can develop into either Th1 or Th2 cytokine secretion phenotype. J. Immunol.153, 3514–3522 (1994). CASPubMed Google Scholar
Viola, A. & Lanzavecchia, A. T cell activation determined by T cell receptor number and tunable thresholds. Science273, 104–106 (1996). CAS Google Scholar
Itoh, Y. & Germain, R.N. Single cell analysis reveals regulated hierarchical T cell antigen receptor signaling thresholds and intraclonal heterogenety for individual cytokine responses of CD4+ T cells. J. Exp. Med.186, 757–766 (1997). CASPubMed Google Scholar
Waldorp, S.L., Davis, K.A., Maino, V.C. & Picker, L.J. Normal human CD4+ memory cells display broad heterogenety in their activation threshold for cytokine synthesis. J. Immunol.161, 5282–5295 (1998). Google Scholar
Weaver, C.T. Heterogeneity in the clonal T cell response: implications for models of T cell activation and cytokine phenotype development. Immunol. Res.17, 279–302 (1998). CASPubMed Google Scholar
Nutt, S.L., Heavey, B., Rolink, A.G. & Busslinger, M. Commitment to B-lymphoid lineage depends on the transcription factor Pax5. Nature401, 556–562 (1999). CASPubMed Google Scholar
Selin, L.K. & Welsh, R.M. Cytolytically active memory CTL present in lymphocytic choriomeningitis virus-immune mice after clearance of virus infection. J. Immunol.158, 5366–5373 (1997). CASPubMed Google Scholar
Opferman, J.T., Ober, B.T. & Ashton-Rickardt, P.G. Linear differentiation of cytotoxic effectors into memory T lymphocytes. Science283, 1745–1748 (1999). CASPubMed Google Scholar
Naramura, M., Hu, R. & Gu, H. Mice with a fluorescent marker for interleukin 2 gene activation. Immunity9, 209–216 (1998). CAS Google Scholar
Saparov, A. et al. Interleukin-2 expression by a subpopulation of primary T cells is linked to enhanced memory/effector function. Immunity11, 271–280 (1999). CASPubMed Google Scholar
Malissen, M. et al. Altered T cell development in mice with a targeted mutation of the CD3 ɛ gene. EMBO J.14, 4641–4653 (1995). CASPubMed Google Scholar
Teh, H.S. et al. Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells. Nature335, 229–233 (1988). CASPubMed Google Scholar
Lyons, A.B. & Parish, C.R. Determination of lymphocyte division by flow cytometry. J. Immunol. Methods.171, 131–137 (1994). CASPubMed Google Scholar
Tafuri, A. et al. Combination of hematopoietic growth factors containing IL-3 induce acute myeloid leukemia cell sensitization to cycle specific and cycle non-specific drugs. Leukemia8, 749–757 (1994). CASPubMed Google Scholar
Loffert, D., Ehlich, A., Muller, W. & Rajewsky, K. Surrogate light chain expression is required to establish immunoglobulin heavy chain allelic exclusion during early B cell development. Immunity4, 133–144 (1996). CASPubMed Google Scholar
Pannetier, C. et al. Quantitative titration of nucleic acids by enymatic amplification reactions run to saturation. Nucleic Acids Res.21, 577–583 (1993). CASPubMed Google Scholar
Taswell, C. Limiting dilution assays for the determination of immunocompetent cell frequencies. III. Validity tests for the single-hit Poisson model. J. Immunol. Methods72, 29–40 (1984). CASPubMed Google Scholar
Siminovitch, L., McCulloch, E.A. & Till, J E. The distribution of colony forming cells among spleen colonies. J. Cell Comp. Physiol.62, 327–336 (1963). CASPubMed Google Scholar