Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer (original) (raw)

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Acknowledgements

We thank A. Rajput and H. Hampel. This work was supported by PHS grants KO8 CA77676 (W.M.G.), RO1 CA67409, RO1 CA72160 (S.M.), P30 CA43703, P30CA16058, CA8485 and DK20593, and by the Health Research Council of New Zealand (P.J.G.). S.M. is an associate investigator of the Howard Hughes Medical Institute.

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Authors and Affiliations

  1. Department of Medicine, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Cleveland , Ohio, USA
    William M. Grady & Sanford Markowitz
  2. Department of Pathology, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Cleveland , Ohio, USA
    Joseph Willis & Kelly Ferguson
  3. Department of Human Genetics, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Cleveland, Ohio, USA
    Georgia Wiesner
  4. Ireland Cancer Center, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Cleveland , Ohio, USA
    Georgia Wiesner & Sanford Markowitz
  5. Department of Biochemistry, Cancer Genetics Laboratory, University of Otago, Dunedin, New Zealand
    Parry J. Guilford, Anita K. Dunbier & Tumi T. Toro
  6. Department of Preventive Medicine, Creighton University Medical School, Omaha, Nebraska, USA
    Henry Lynch
  7. Clinical Cancer Genetics and Human Cancer Genetics Programs, Comprehensive Cancer Center, and Division of Human Genetics, Department of Internal Medicine, Ohio State University Medical School, Columbus , Ohio, USA
    Charis Eng
  8. Department of Surgery, Seoul National University Hospital, Seoul, Korea
    Jae-Gahb Park
  9. Laboratory of Cell Regulation and Carcinogenesis, National Cancer Institute, NIH, Bethesda, Maryland, USA
    Seong-Jin Kim
  10. Howard Hughes Medical Institute, Cleveland , Ohio, USA
    Sanford Markowitz

Authors

  1. William M. Grady
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  2. Joseph Willis
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  3. Parry J. Guilford
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  4. Anita K. Dunbier
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  5. Tumi T. Toro
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  6. Henry Lynch
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  7. Georgia Wiesner
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  8. Kelly Ferguson
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  9. Charis Eng
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  10. Jae-Gahb Park
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  11. Seong-Jin Kim
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  12. Sanford Markowitz
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Corresponding author

Correspondence toSanford Markowitz.

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Grady, W., Willis, J., Guilford, P. et al. Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer.Nat Genet 26, 16–17 (2000). https://doi.org/10.1038/79120

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