Guilt by association (original) (raw)

Nature Genetics volume 26, pages 135–137 (2000)Cite this article

Positional cloning of common disease genes is a central but elusive goal of human geneticists. Progress is now reported by Bell and colleagues in their study of NIDDM1, a locus implicated in type 2 diabetes. The complex nature of the reported association illustrates the challenge of implicating a specific gene and mutation in the causation of polygenic disease.

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Authors and Affiliations

  1. Departments of Genetics and Medicine, Harvard Medical School, Boston, Massachusetts, USA
    David Altshuler
  2. Department of Molecular Biology and Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts , USA
    David Altshuler
  3. Whitehead Institute/MIT Center for Genome Research , Cambridge, Massachusetts, USA
    David Altshuler & Mark Daly
  4. Howard Hughes Medical Institute, Program in Genetics, Fred Hutchison Cancer Center, Seattle, Washington, USA
    Leonid Kruglyak
  5. Division of Human Biology, Program in Genetics, Fred Hutchison Cancer Center, Seattle, Washington, USA
    Leonid Kruglyak

Authors

  1. David Altshuler
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  2. Mark Daly
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  3. Leonid Kruglyak
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Altshuler, D., Daly, M. & Kruglyak, L. Guilt by association.Nat Genet 26, 135–137 (2000). https://doi.org/10.1038/79839

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