A major susceptibility locus for atopic dermatitis maps to chromosome 3q21 (original) (raw)

• Hanifin, J.M. Atopic Dermatitis (Mosby, St. Louis, 1998).
  Google Scholar
• Bergmann, R.L. et al. Atopic dermatitis in early infancy predicts allergic airway disease at 5 years. Clin. Exp. Allergy 28, 965–970 (1998).
  Article CAS PubMed Google Scholar
• Cox, H.E. et al. Association of atopic dermatitis to the β subunit of the high affinity immunoglobulin E receptor. Br. J. Dermatol. 138, 182–187 (1998).
  Article CAS PubMed Google Scholar
• Kay, J., Gawkrodger, D.J., Mortimer, M.J. & Jaron, A.G. The prevalence of childhood atopic eczema in a general population. J. Am. Acad. Dermatol. 30, 35–39 (1994).
  Article CAS PubMed Google Scholar
• Taylor, B., Wadsworth, J., Wadsworth, M. & Peckham, C. Changes in the reported prevalence of childhood eczema since the 1939–45 war. Lancet 2, 1255–1257 (1984).
  Article CAS PubMed Google Scholar
• Cookson, W. The alliance of genes and environment in asthma and allergy. Nature 402, B5–11 (1999).
  Article Google Scholar
• Larsen, F.S., Holm, N.V. & Henningsen, K. Atopic dermatitis. A genetic-epidemiologic study in a population-based twin sample. J. Am. Acad. Dermatol. 15, 487–494 (1986).
  Article CAS PubMed Google Scholar
• Hanifin, J.M. & Rajka, G. Diagnostic features of atopic dermatitis. Acta Derm. (Stockh.) 92, 44–47 (1980).
  Google Scholar
• Leung, D.Y. et al. Disease management of atopic dermatitis: a practice parameter. Joint Task Force on Practice Parameters, representing the American Academy of Allergy, Asthma and Immunology, the American College of Allergy, Asthma and Immunology, and the Joint Council of Allergy, Asthma and Immunology. Work Group on Atopic Dermatitis. Ann. Allergy Asthma Immunol. 79, 197–211 (1997).
  Article CAS PubMed Google Scholar
• Daniels, S.E. et al. A genome-wide search for quantitative trait loci underlying asthma. Nature 383, 247–250 (1996).
  Article CAS PubMed Google Scholar
• The Collaborative Study on the Genetics of Asthma (CSGA). A genome-wide search for asthma susceptibility loci in ethnically diverse populations. Nature Genet. 15, 389–392 (1997).
• Ober, C. et al. Genome-wide search for asthma susceptibility loci in a founder population. The Collaborative Study on the Genetics of Asthma. Hum. Mol. Genet. 7, 1393–1398 (1998).
  Article CAS PubMed Google Scholar
• Wjst, M. et al. A genome-wide search for linkage to asthma. German Asthma Genetics Group. Genomics 58, 1–8 (1999).
  Article CAS PubMed Google Scholar
• Kunz, B. et al. Clinical validation and guidelines for the SCORAD index: consensus report of the European Task Force on Atopic Dermatitis. Dermatology 195, 10–19 (1997).
  Article CAS PubMed Google Scholar
• Dold, S., Wjst, M., von Mutius, E., Reitmeir, P. & Stiepel, E. Genetic risk for asthma, allergic rhinitis, and atopic dermatitis. Arch. Dis. Child. 67, 1018–1022 (1992).
  Article CAS PubMed PubMed Central Google Scholar
• Mao, X.Q. et al. Association between genetic variants of mast-cell chymase and eczema. Lancet 348, 581–583 (1996).
  Article CAS PubMed Google Scholar
• Hershey, G.K., Friedrich, M.F., Esswein, L.A., Thomas, M.L. & Chatila, T.A. The association of atopy with a gain-of-function mutation in the α subunit of the interleukin-4 receptor. N. Engl. J. Med. 337, 1720–1725 (1997).
  Article CAS PubMed Google Scholar
• Nickel, R.G. et al. Atopic dermatitis is associated with a functional mutation in the promoter of the C-C chemokine RANTES. J. Immunol. 164, 1612–1616 (2000).
  Article CAS PubMed Google Scholar
• Abreu, P.C., Greenberg, D.A. & Hodge, S.E. Direct power comparisons between simple LOD scores and NPL scores for linkage analysis in complex diseases. Am. J. Hum. Genet. 65, 847–857 (1999).
  Article CAS PubMed PubMed Central Google Scholar
• Moffatt, M.F. & Cookson, W.O. The genetics of asthma. Maternal effects in atopic disease. Clin. Exp. Allergy 28, 56–61 (1998).
  Article PubMed Google Scholar
• Kuchroo, V.K. et al. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell 80, 707–718 (1995).
  Article CAS PubMed Google Scholar
• Lanier, L.L. et al. CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL. J. Immunol. 154, 97–105 (1995).
  CAS PubMed Google Scholar
• Dib, C. et al. A comprehensive genetic map of the human genome based on 5,264 microsatellites. Nature 380, 152–154 (1996).
  Article CAS PubMed Google Scholar
• O'Connell, J.R. & Weeks, D.E. PedCheck: a program for identification of genotype incompatibilities in linkage analysis. Am. J. Hum. Genet. 63, 259–266 (1998).
  Article CAS PubMed PubMed Central Google Scholar
• Kruglyak, L., Daly, M.J., Reeve-Daly, M.P. & Lander, E.S. Parametric and nonparametric linkage analysis: a unified multipoint approach. Am. J. Hum. Genet. 58, 1347–1363 (1996).
  CAS PubMed PubMed Central Google Scholar
• Conneally, P.M. et al. Report of the Committee on Methods of Linkage Analysis and Reporting. Cytogenet. Cell Genet. 40, 356–359 (1985).
  Article CAS PubMed Google Scholar
• Kong, A. & Cox, N.J. Allele-sharing models: LOD scores and accurate linkage tests. Am. J. Hum. Genet. 61, 1179–1188 (1997).
  Article CAS PubMed PubMed Central Google Scholar
• Strauch, K. et al. Parametric and nonparametric multipoint linkage analysis with imprinting and two-locus-trait models: application to mite sensitization. Am. J. Hum. Genet. 66, 1945–1957 (2000).
  Article CAS PubMed PubMed Central Google Scholar
• Gudbjartsson, D.F., Jonasson, K., Frigge, M.L. & Kong, A. Allegro, a new computer program for multipoint linkage analysis. Nature Genet. 25, 12–13 (2000).
  Article CAS PubMed Google Scholar
• Lander, E. & Kruglyak, L. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nature Genet. 11, 241–247 (1995).
  Article CAS PubMed Google Scholar