The function of a stem-loop in telomerase RNA is linked to the DNA repair protein Ku (original) (raw)
Bryan, T.M. & Cech, T.R. Telomerase and the maintenance of chromosome ends. Curr. Opin. Cell Biol.11, 318–324 (1999). ArticleCASPubMed Google Scholar
Singer, M.S. & Gottschling, D.E. TLC1 : template RNA component of Saccharomyces cerevisiae telomerase. Science266, 404–409 ( 1994). ArticleCASPubMed Google Scholar
Singer, M.S. et al. Identification of high copy disruptors of telomeric silencing in Saccharomyces cerevisiae. Genetics150, 613–632 (1998). CASPubMedPubMed Central Google Scholar
Tuteja, R. & Tuteja, N. Ku autoantigen: a multifunctional DNA-binding protein. Crit. Rev. Biochem. Mol. Biol.35, 1–33 (2000). ArticleCASPubMed Google Scholar
Singer, M.S. Genetic Studies of Telomere Position Effect and the Identification of the Telomerase Template RNA in Saccharomyces cerevisiae Thesis, Univ. Chicago (1997). Google Scholar
Lingner, J. et al. Reverse transcriptase motifs in the catalytic subunit of telomerase . Science276, 561–567 (1997). ArticleCASPubMed Google Scholar
Lin, J.J. & Zakian, V.A. An in vitro assay for Saccharomyces telomerase requires EST1. Cell81, 1127–1135 (1995). ArticleCASPubMed Google Scholar
Steiner, B.R., Hidaka, K. & Futcher, B. Association of the Est1 protein with telomerase activity in yeast. Proc. Natl. Acad. Sci. USA93, 2817–2821 (1996). ArticleCASPubMedPubMed Central Google Scholar
Evans, S.K. & Lundblad, V. Est1 and Cdc13 as comediators of telomerase access. Science286, 117– 120 (1999). ArticleCASPubMed Google Scholar
Nugent, C.I. et al. Telomere maintenance is dependent on activities required for end repair of double-strand breaks. Curr. Biol.8, 657–660 (1998). ArticleCASPubMed Google Scholar
Polotnianka, R.M., Li, J. & Lustig, A.J. The yeast Ku heterodimer is essential for protection of the telomere against nucleolytic and recombinational activities. Curr. Biol.8, 831–834 ( 1998). ArticleCASPubMed Google Scholar
Critchlow, S.E. & Jackson, S.P. DNA end-joining: from yeast to man. Trends Biochem. Sci.23, 394–398 (1998). ArticleCASPubMed Google Scholar
Palladino, F. et al. SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres. Cell75, 543 –555 (1993). ArticleCASPubMed Google Scholar
Muniyappa, K. & Kironmai, K.M. Telomere structure, replication and length maintenance. Crit. Rev. Biochem. Mol. Biol.33, 297–336 (1998). ArticleCASPubMed Google Scholar
Feldmann, H. et al. HDF2, the second subunit of the Ku homologue from Saccharomyces cerevisiae. J. Biol. Chem.271, 27765 –27769 (1996). ArticleCASPubMed Google Scholar
Gravel, S., Larrivee, M., Labrecque, P. & Wellinger, R.J. Yeast Ku as a regulator of chromosomal DNA end structure. Science280, 741–744 ( 1998). ArticleCASPubMed Google Scholar
Dynan, W.S. & Yoo, S. Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids. Nucleic Acids Res.26, 1551–1559 ( 1998). ArticleCASPubMedPubMed Central Google Scholar
Haber, J.E. & Thorburn, P.C. Healing of broken linear dicentric chromosomes in yeast. Genetics106, 207– 226 (1984). CASPubMedPubMed Central Google Scholar
Costanzo, M.C. et al. The yeast proteome database (YPD) and Caenorhabditis elegans proteome database (WormPD): comprehensive resources for the organization and comparison of model organism protein information. Nucleic Acids Res.28, 73–76 ( 2000). ArticleCASPubMedPubMed Central Google Scholar
Sikorski, R.S. & Hieter, P. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics122, 19–27 (1989). CASPubMedPubMed Central Google Scholar
Potter, P.M. Directional PCR cloning of multiple repeat sequences. Biotechniques21, 198–200 ( 1996). ArticleCASPubMed Google Scholar
Diede, S.J. & Gottschling, D.E. Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases α and δ . Cell99, 723–733 (1999). ArticleCASPubMed Google Scholar
Rothstein, R. Targeting, disruption, replacement, and allele rescue: integrative DNA transformation in yeast. Methods Enzymol.194, 281– 301 (1991). ArticleCASPubMed Google Scholar
Runge, K.W. & Zakian, V.A. TEL2, an essential gene required for telomere length regulation and telomere position effect in Saccharomyces cerevisiae. Mol. Cell. Biol.16, 3094–3105 (1996). ArticleCASPubMedPubMed Central Google Scholar
Mumberg, D., Muller, R. & Funk, M. Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds. Gene156 , 119–122 (1995). ArticleCASPubMed Google Scholar
Brachmann, C.B. et al. Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications. Yeast14, 115– 132 (1998). ArticleCASPubMed Google Scholar
Sikorski, R.S. & Boeke, J.D. In vitro mutagenesis and plasmid shuffling: from cloned gene to mutant yeast. Methods Enzymol.194, 302–318 (1991). ArticleCASPubMed Google Scholar
Dionne, I. & Wellinger, R.J. Cell cycle-regulated generation of single-stranded G-rich DNA in the absence of telomerase. Proc. Natl. Acad. Sci. USA93, 13902–13907 (1996). ArticleCASPubMedPubMed Central Google Scholar
Friedman, K.L. & Cech, T.R. Essential functions of amino-terminal domains in the yeast telomerase catalytic subunit revealed by selection for viable mutants. Genes Dev.13, 2863–2874 (1999). ArticleCASPubMedPubMed Central Google Scholar
Mathews, D.H., Sabina, J., Zuker, M. & Turner, D.H. Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure. J. Mol. Biol.288, 911– 940 (1999). ArticleCASPubMed Google Scholar