Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL (original) (raw)

• Sporn, M.B., Roberts, A.B. & Goodman, D.S. The Retinoids: Biology, Chemistry and Medicine. (Raven, New York, 1994).
  Google Scholar
• Kastner, P., Mark, M. & Chambon, P. Nonsteroid nuclear receptors: What are genetic studies telling us about their role in real life? Cell 83, 859–869 (1995).
  Article CAS Google Scholar
• Verma, A.K. Inhibition of both stage I and stage II mouse skin tumour promotion by retinoic acid and the dependence of inhibition of tumor promotion on the duration of retinoic acid treatment. Cancer Res. 47, 5097–5101 (1987).
  CAS PubMed Google Scholar
• Lippman, S.M. et al. 13-_cis_-retinoic acid plus interferon α-2a: highly active systemic therapy for squamous cell carcinoma of the cervix. J. Natl. Cancer Inst. 84, 241–245 (1992).
  Article CAS Google Scholar
• Lippman, S.M. et al. 13-_cis_-retinoic acid and interferon α-2a: effective combination therapy for advanced squamous cell carcinoma of the skin. J. Natl. Cancer Inst. 84, 235–241 (1992).
  Article CAS Google Scholar
• Bonhomme, L. et al. Topical treatment of epidemic Kaposi's sarcoma with all-_trans_-retinoic acid. Ann. Oncol. 2, 234–235 (1991).
  Article CAS Google Scholar
• Fenaux, P. & Degos, L. Differentiation therapy for acute promyelocytic leukemia. N. Engl. J. Med. 337, 1076–1077 (1997).
  Article CAS Google Scholar
• Slack, J.L. & Gallagher, R.E. The molecular biology of acute promyelocytic leukemia. Cancer Treat. Res. 99, 75–124 (1999).
  Article CAS Google Scholar
• Minucci, S. & Pelicci, P.G. Retinoid receptors in health and disease: co-regulators and the chromatin connection. Semin. Cell. Dev. Biol. 10, 215–225 (1999).
  Article CAS Google Scholar
• Lotan, R. Retinoids in cancer chemoprevention. FASEB J. 10, 1031–1039 (1996).
  Article CAS Google Scholar
• Hong, W.K. & Sporn, M.B. Recent advances in chemoprevention of cancer. Science 278, 1073–1077 (1997).
  Article CAS Google Scholar
• International Agency for Research on Cancer. IARC Handbooks of Cancer Prevention Vol. 4: Retinoids. (IARC, Lyon, France, 1999).
• Lanotte, M. et al. NB4, a maturation inducible cell line with t(15;17) marker isolated from a human acute promyelocytic leukemia (M3). Blood 77, 1080–1086 (1991).
  CAS PubMed Google Scholar
• Chen, J.Y. et al. Two distinct actions of retinoid-receptor ligands. Nature 382, 819–822 (1996).
  Article CAS Google Scholar
• Gehin, M. et al. Structural basis for engineering of retinoic acid receptor isotype- selective agonists and antagonists. Chem. Biol. 6, 519–529 (1999).
  Article CAS Google Scholar
• Benoit, G. et al. RAR-independent RXR signaling induces t(15;17) leukemia cell maturation. EMBO J. 18, 7011–7018 (1999).
  Article CAS Google Scholar
• Moreb, J.S. & Schweder, M. Human A1, a Bcl-2-related gene, is induced in leukemic cells by cytokines as well as differentiating factors. Leukemia 11, 998–1004 (1997).
  Article CAS Google Scholar
• Bruel, A., Benoit, G., De Nay, D., Brown, S. & Lanotte, M. Distinct apoptotic responses in maturation sensitive and resistant t(15;17) acute promyelocytic leukemia NB4 cells. 9-cis retinoic acid induces apoptosis independent of maturation and Bcl-2 expression. Leukemia 9, 1173–1184 (1995).
  CAS PubMed Google Scholar
• Deveraux, Q.L. & Reed, J.C. IAP family proteins—suppressors of apoptosis. Genes Dev. 13, 239–52 (1999).
  Article CAS Google Scholar
• Wang, C.Y., Mayo, M.W., Korneluk, R.G., Goeddel, D.V. & Baldwin, A.S. Jr . NF-κB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 281, 1680–1683 (1998).
  Article CAS Google Scholar
• Schneider, P. et al. Conversion of membrane-bound Fas (CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity. J. Exp. Med. 187, 1205–1213 (1998).
  Article CAS Google Scholar
• Ashkenazi, A. & Dixit, V.M. Apoptosis control by death and decoy receptors. Curr. Opin. Cell. Biol. 11, 255–260 (1999).
  Article CAS Google Scholar
• Walczak, H. & Krammer, P.H. The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems. Exp. Cell. Res. 256, 58–66 (2000).
  Article CAS Google Scholar
• Tucker, K.A., Lilly, M.B., Heck, L. & Rado, T.A. Characterization of a new human diploid myeloid leukemia cell line (PLB-985) with granulocytic and monocytic differentiating capacity. Blood 70, 372–378 (1987).
  CAS PubMed Google Scholar
• Bodmer, J.L. et al. TRAIL receptor-2 signals apoptosis through FADD and caspase-8. Nature Cell Biol. 2, 241–243 (2000).
  Article CAS Google Scholar
• Kischkel, F.C. et al. Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5. Immunity 12, 611–620 (2000).
  Article CAS Google Scholar
• Sprick, M.R. et al. FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2. Immunity 12, 599–609 (2000).
  Article CAS Google Scholar
• Wang, J. et al. Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II. Cell 98, 47–58 (1999).
  Article CAS Google Scholar
• Pan, G. et al. The receptor for the cytotoxic ligand TRAIL. Science 276, 111–113 (1997).
  Article CAS Google Scholar
• Nagy, L. et al. Activation of retinoid X receptors induces apoptosis in HL-60 cell lines. Mol. Cell. Biol. 15, 3540–3551 (1995).
  Article CAS Google Scholar
• Wen, J. et al. Antileukemic drugs increase death receptor 5 levels and enhance Apo-2L- induced apoptosis of human acute leukemia cells. Blood 96, 3900–3906 (2000).
  CAS PubMed Google Scholar
• Sun, S.Y., Yue, P., Hong, W.K. & Lotan, R. Augmentation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by the synthetic retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) through up-regulation of TRAIL receptors in human lung cancer cells. Cancer Res. 60, 7149–7155 (2000).
  CAS PubMed Google Scholar
• Raff, M.C. et al. Programmed cell death and the control of cell survival: lessons from the nervous system. Science 262, 695–700 (1993).
  Article CAS Google Scholar
• Zong, W.X., Edelstein, L.C., Chen, C., Bash, J. & Gelinas, C. The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-κB that blocks TNF-α–induced apoptosis. Genes Dev. 13, 382–387 (1999).
  Article CAS Google Scholar
• Grumont, R.J., Rourke, I.J. & Gerondakis, S. Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis. Genes Dev8 13, 400–411 (1999).
  Article CAS Google Scholar
• Chu, Z.L. et al. Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-κB control. Proc. Natl. Acad. Sci. USA 94, 10057–10062 (1997).
  Article CAS Google Scholar
• You, M., Ku, P.T., Hrdlickova, R. & Bose, H.R., Jr . ch-IAP1, a member of the inhibitor-of-apoptosis protein family, is a mediator of the antiapoptotic activity of the v-Rel oncoprotein. Mol. Cell. Biol. 17, 7328–7341 (1997).
  Article CAS Google Scholar
• Pomerantz, J.L. & Baltimore, D. Signal transduction. A cellular rescue team. Nature 406, 26–27 (2000).
  Article CAS Google Scholar
• Gianni, M. et al. Retinoid-dependent growth inhibition, differentiation and apoptosis in acute promyelocytic leukemia cells. Expression and activation of caspases. Cell Death Differ. 7, 447–460 (2000).
  Article CAS Google Scholar
• Sun, S.Y. et al. Dual mechanisms of action of the retinoid CD437: nuclear retinoic acid receptor-mediated suppression of squamous differentiation and receptor- independent induction of apoptosis in UMSCC22B human head and neck squamous cell carcinoma cells. Mol. Pharmacol. 58, 508–514 (2000).
  Article CAS Google Scholar
• Walczak, H. et al. Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nature Med. 5, 157–163 (1999).
  Article CAS Google Scholar
• Ashkenazi, A. et al. Safety and antitumor activity of recombinant soluble Apo2 ligand. J. Clin. Invest. 104, 155–162 (1999).
  Article CAS Google Scholar
• Zamai, L. et al. TNF-related apoptosis-inducing ligand (TRAIL) as a negative regulator of normal human erythropoiesis. Blood 95, 3716–3724 (2000).
  CAS PubMed Google Scholar
• Chomienne, C. et al. All-trans retinoic acid in acute promyelocytic leukemias. II. In vitro studies: structure-function relationship. Blood 76, 1710–1717 (1990).
  CAS PubMed Google Scholar