Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia (original) (raw)
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Acknowledgements
We thank C. Lee, IWK Grace Health Centre, Halifax, NS, and E. Separovic, British Columbia Children's Hospital, Vancouver, BC, Canada, for help in identifying leukemia cell samples; J. Skaug and The Centre for Applied Genomics at The Hospital for Sick Children for excellent technical assistance; I. Herrington and V. Audino for manuscript preparation; and J. Downing and J. Dick for comments regarding the manuscript. This research was supported in part by grant CA-87064 (to S.W.M.) and Cancer Center Support (CORE) grant CA-27165, both from the National Cancer Institute, by the American Lebanese Syrian Associated Charities (ALSAC), St Jude Children's Research Hospital, and by The Hospital for Sick Children Foundation. S.W.S. is the recipient of a CIHR Scholar Award.
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Authors and Affiliations
- Department of Pathology, St Jude Children's Research Hospital, Memphis, 38105, Tennessee, USA
Zhigui Ma, Stephan W. Morris & Xiaoli Cui - Department of Tumor Cell Biology, St Jude Children's Research Hospital, Memphis, 38105, Tennessee, USA
Virginia Valentine - Department of Hematology/Oncology, St Jude Children's Research Hospital, Memphis, 38105, Tennessee, USA
Stephan W. Morris - Hartwell Center for Bioinformatics and Biotechnology, St Jude Children's Research Hospital, Memphis, 38105, Tennessee, USA
Perdeep K. Mehta - Department of Pediatrics, University of Tennessee, College of Medicine, Memphis, 38163, Tennessee, USA
Stephan W. Morris - Centre for Applied Molecular Biology, School of Pharmacy, University of London, WC1N 1AX, UK
Dean Nizetic - Department of Cancer Chemotherapy, Saitama Cancer Center Hospital, Ina, 363-0806, Saitama, Japan
Yasuhiko Kaneko - Department of Paediatrics, Division of Haematology, Queen Mary Hospital, University of Hong Kong, PRC
Godfrey C.F. Chan - Department of Pathology, Division of Haematology, Queen Mary Hospital, University of Hong Kong, PRC
Li C. Chan - Department of Paediatrics, Division of Haematology/Oncology, The Hospital for Sick Children, University of Toronto, Toronto, M5G 1X8, Ontario, Canada
Johann K. Hitzler - Department of Cancer and Blood, The Hospital for Sick Children, University of Toronto, Toronto, M5G 1X8, Ontario, Canada
Yue Li & Johann K. Hitzler - Department of Genetics, The Hospital for Sick Children, University of Toronto, Toronto, M5G 1X8, Ontario, Canada
Martin L, Jo-Anne Herbrick & Stephen W. Scherer - Department of Medical Biophysics, University of Toronto, Toronto, M5S 1A8, Ontario, Canada
Jeremy Squire - Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, M5S 1A8, Ontario, Canada
Derek Bouman & Jeremy Squire - Department of Molecular and Medical Genetics, University of Toronto, Toronto, M5S 1A8, Ontario, Canada
Stephen W. Scherer
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- Zhigui Ma
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Correspondence toStephan W. Morris or Johann K. Hitzler.
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Ma, Z., Morris, S., Valentine, V. et al. Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia.Nat Genet 28, 220–221 (2001). https://doi.org/10.1038/90054
- Received: 01 May 2001
- Accepted: 01 June 2001
- Issue Date: July 2001
- DOI: https://doi.org/10.1038/90054