Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia (original) (raw)

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Acknowledgements

We thank C. Lee, IWK Grace Health Centre, Halifax, NS, and E. Separovic, British Columbia Children's Hospital, Vancouver, BC, Canada, for help in identifying leukemia cell samples; J. Skaug and The Centre for Applied Genomics at The Hospital for Sick Children for excellent technical assistance; I. Herrington and V. Audino for manuscript preparation; and J. Downing and J. Dick for comments regarding the manuscript. This research was supported in part by grant CA-87064 (to S.W.M.) and Cancer Center Support (CORE) grant CA-27165, both from the National Cancer Institute, by the American Lebanese Syrian Associated Charities (ALSAC), St Jude Children's Research Hospital, and by The Hospital for Sick Children Foundation. S.W.S. is the recipient of a CIHR Scholar Award.

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Authors and Affiliations

1. Department of Pathology, St Jude Children's Research Hospital, Memphis, 38105, Tennessee, USA
   Zhigui Ma, Stephan W. Morris & Xiaoli Cui
2. Department of Tumor Cell Biology, St Jude Children's Research Hospital, Memphis, 38105, Tennessee, USA
   Virginia Valentine
3. Department of Hematology/Oncology, St Jude Children's Research Hospital, Memphis, 38105, Tennessee, USA
   Stephan W. Morris
4. Hartwell Center for Bioinformatics and Biotechnology, St Jude Children's Research Hospital, Memphis, 38105, Tennessee, USA
   Perdeep K. Mehta
5. Department of Pediatrics, University of Tennessee, College of Medicine, Memphis, 38163, Tennessee, USA
   Stephan W. Morris
6. Centre for Applied Molecular Biology, School of Pharmacy, University of London, WC1N 1AX, UK
   Dean Nizetic
7. Department of Cancer Chemotherapy, Saitama Cancer Center Hospital, Ina, 363-0806, Saitama, Japan
   Yasuhiko Kaneko
8. Department of Paediatrics, Division of Haematology, Queen Mary Hospital, University of Hong Kong, PRC
   Godfrey C.F. Chan
9. Department of Pathology, Division of Haematology, Queen Mary Hospital, University of Hong Kong, PRC
   Li C. Chan
10. Department of Paediatrics, Division of Haematology/Oncology, The Hospital for Sick Children, University of Toronto, Toronto, M5G 1X8, Ontario, Canada
    Johann K. Hitzler
11. Department of Cancer and Blood, The Hospital for Sick Children, University of Toronto, Toronto, M5G 1X8, Ontario, Canada
    Yue Li & Johann K. Hitzler
12. Department of Genetics, The Hospital for Sick Children, University of Toronto, Toronto, M5G 1X8, Ontario, Canada
    Martin L, Jo-Anne Herbrick & Stephen W. Scherer
13. Department of Medical Biophysics, University of Toronto, Toronto, M5S 1A8, Ontario, Canada
    Jeremy Squire
14. Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, M5S 1A8, Ontario, Canada
    Derek Bouman & Jeremy Squire
15. Department of Molecular and Medical Genetics, University of Toronto, Toronto, M5S 1A8, Ontario, Canada
    Stephen W. Scherer

Authors

1. Zhigui Ma
2. Stephan W. Morris
3. Virginia Valentine
4. Martin L
5. Jo-Anne Herbrick
6. Xiaoli Cui
7. Derek Bouman
8. Yue Li
9. Perdeep K. Mehta
10. Dean Nizetic
11. Yasuhiko Kaneko
12. Godfrey C.F. Chan
13. Li C. Chan
14. Jeremy Squire
15. Stephen W. Scherer
16. Johann K. Hitzler

Corresponding authors

Correspondence toStephan W. Morris or Johann K. Hitzler.

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Ma, Z., Morris, S., Valentine, V. et al. Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia.Nat Genet 28, 220–221 (2001). https://doi.org/10.1038/90054

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• Received: 01 May 2001
• Accepted: 01 June 2001
• Issue Date: July 2001
• DOI: https://doi.org/10.1038/90054