PDGF-B gene therapy accelerates bone engineering and oral implant osseointegration (original) (raw)
Wikesjo UM, Sorensen RG, Wozney JM . Augmentation of alveolar bone and dental implant osseointegration: clinical implications of studies with rhBMP-2. J Bone Joint Surg Am 2001; 83-A (Suppl 1): S136–S145. Google Scholar
Lynch SE, de Castilla GR, Williams RC, Kiritsy CP, Howell TH, Reddy MS et al. The effects of short-term application of a combination of platelet-derived and insulin-like growth factors on periodontal wound healing. J Periodontol 1991; 62: 458–467. ArticleCAS Google Scholar
Fang J, Zhu YY, Smiley E, Bonadio J, Rouleau JP, Goldstein SA et al. Stimulation of new bone formation by direct transfer of osteogenic plasmid genes. Proc Natl Acad Sci USA 1996; 93: 5753–5758. ArticleCAS Google Scholar
Ramseier CA, Abramson ZR, Jin Q, Giannobile WV . Gene therapeutics for periodontal regenerative medicine. Dent Clin North Am 2006; 50: 245–263, ix. Article Google Scholar
Ghosh SS, Gopinath P, Ramesh A . Adenoviral vectors: a promising tool for gene therapy. Appl Biochem Biotechnol 2006; 133: 9–29. ArticleCAS Google Scholar
Chang PC, Cirelli JA, Jin Q, Seol YJ, Sugai JV, D'Silva NJ et al. Adenovirus encoding human platelet-derived growth factor-B delivered to alveolar bone defects exhibits safety and biodistribution profiles favorable for clinical use. Hum Gene Ther 2009; 20: 486–496. ArticleCAS Google Scholar
Gu DL, Nguyen T, Gonzalez AM, Printz MA, Pierce GF, Sosnowski BA et al. Adenovirus encoding human platelet-derived growth factor-B delivered in collagen exhibits safety, biodistribution, and immunogenicity profiles favorable for clinical use. Mol Ther 2004; 9: 699–711. ArticleCAS Google Scholar
Barrientos S, Stojadinovic O, Golinko MS, Brem H, Tomic-Canic M . Growth factors and cytokines in wound healing. Wound Repair Regen 2008; 16: 585–601. Article Google Scholar
Anusaksathien O, Jin Q, Zhao M, Somerman MJ, Giannobile WV . Effect of sustained gene delivery of platelet-derived growth factor or its antagonist (PDGF-1308) on tissue-engineered cementum. J Periodontol 2004; 75: 429–440. ArticleCAS Google Scholar
Canalis E, McCarthy TL, Centrella M . Effects of platelet-derived growth factor on bone formation in vitro. J Cell Physiol 1989; 140: 530–537. ArticleCAS Google Scholar
Nevins M, Giannobile WV, McGuire MK, Kao RT, Mellonig JT, Hinrichs JE et al. Platelet-derived growth factor stimulates bone fill and rate of attachment level gain: results of a large multicenter randomized controlled trial. J Periodontol 2005; 76: 2205–2215. ArticleCAS Google Scholar
Uhl E, Rosken F, Sirsjo A, Messmer K . Influence of platelet-derived growth factor on microcirculation during normal and impaired wound healing. Wound Repair Regen 2003; 11: 361–367. Article Google Scholar
Simion M, Rocchietta I, Monforte M, Maschera E . Three-dimensional alveolar bone reconstruction with a combination of recombinant human platelet-derived growth factor BB and guided bone regeneration: a case report. Int J Periodontics Restorative Dent 2008; 28: 239–243. PubMed Google Scholar
Jin Q, Anusaksathien O, Webb SA, Printz MA, Giannobile WV . Engineering of tooth-supporting structures by delivery of PDGF gene therapy vectors. Mol Ther 2004; 9: 519–526. ArticleCAS Google Scholar
Chang PC, Seol YJ, Kikuchi N, Goldstein SA, Giannobile WV . Functional apparent moduli: Indicators to predict dynamics of oral implant osseointegration (in review).
Gabet Y, Müller R, Levy J, Dimarchi R, Chorev M, Bab I et al. Parathyroid hormone 1-34 enhances titanium implant anchorage in low-density trabecular bone: a correlative micro-computed tomographic and biomechanical analysis. Bone 2006; 39: 276–282. ArticleCAS Google Scholar
Ramp LC, Jeffcoat RL . Dynamic behavior of implants as a measure of osseointegration. Int J Oral Maxillofac Implants 2001; 16: 637–645. CASPubMed Google Scholar
Lin Z, Sugai JV, Jin Q, Chandler LA, Giannobile WV . Platelet-derived growth factor-B gene delivery sustains gingival fibroblast signal transduction. J Periodontal Res 2008; 43: 440–449. ArticleCAS Google Scholar
De Donatis A, Comito G, Buricchi F, Vinci MC, Parenti A, Caselli A et al. Proliferation versus migration in platelet-derived growth factor signaling: the key role of endocytosis. J Biol Chem 2008; 283: 19948–19956. ArticleCAS Google Scholar
Hsieh SC, Graves DT . Pulse application of platelet-derived growth factor enhances formation of a mineralizing matrix while continuous application is inhibitory. J Cell Biochem 1998; 69: 169–180. ArticleCAS Google Scholar
Tokunaga A, Oya T, Ishii Y, Motomura H, Nakamura C, Ishizawa S et al. PDGF receptor beta is a potent regulator of mesenchymal stromal cell function. J Bone Miner Res 2008; 23: 1519–1528. ArticleCAS Google Scholar
Kono SJ, Oshima Y, Hoshi K, Bonewald LF, Oda H, Nakamura K et al. Erk pathways negatively regulate matrix mineralization. Bone 2007; 40: 68–74. ArticleCAS Google Scholar
Huang Z, Nelson ER, Smith RL, Goodman SB . The sequential expression profiles of growth factors from osteoprogenitors (correction of osteroprogenitors) to osteoblasts in vitro. Tissue Eng 2007; 13: 2311–2320. ArticleCAS Google Scholar
Ng F, Boucher S, Koh S, Sastry KS, Chase L, Lakshmipathy U et al. PDGF, TGF-beta, and FGF signaling is important for differentiation and growth of mesenchymal stem cells (MSCs): transcriptional profiling can identify markers and signaling pathways important in differentiation of MSCs into adipogenic, chondrogenic, and osteogenic lineages. Blood 2008; 112: 295–307. ArticleCAS Google Scholar
Kratchmarova I, Blagoev B, Haack-Sorensen M, Kassem M, Mann M . Mechanism of divergent growth factor effects in mesenchymal stem cell differentiation. Science 2005; 308: 1472–1477. ArticleCAS Google Scholar
Doukas J, Chandler LA, Gonzalez AM, Gu D, Hoganson DK, Ma C et al. Matrix immobilization enhances the tissue repair activity of growth factor gene therapy vectors. Hum Gene Ther 2001; 12: 783–798. ArticleCAS Google Scholar
Pouton CW, Wagstaff KM, Roth DM, Moseley GW, Jans DA . Targeted delivery to the nucleus. Adv Drug Deliv Rev 2007; 59: 698–717. ArticleCAS Google Scholar
Dunn CA, Jin Q, Taba Jr M, Franceschi RT, Bruce Rutherford R, Giannobile WV . BMP gene delivery for alveolar bone engineering at dental implant defects. Mol Ther 2005; 11: 294–299. ArticleCAS Google Scholar
Andrae J, Gallini R, Betsholtz C . Role of platelet-derived growth factors in physiology and medicine. Genes Dev 2008; 22: 1276–1312. ArticleCAS Google Scholar
Tokuda H, Takai S, Hanai Y, Harada A, Matsushima-Nishiwaki R, Kato H et al. Potentiation by platelet-derived growth factor-BB of FGF-2-stimulated VEGF release in osteoblasts. J Bone Miner Metab 2008; 26: 335–341. ArticleCAS Google Scholar
Zhang J, Cao R, Zhang Y, Jia T, Cao Y, Wahlberg E . Differential roles of PDGFR-{alpha} and PDGFR-{beta} in angiogenesis and vessel stability. FASEB J 2008; 23: 153–163. Article Google Scholar
Douglas JT . Adenoviral vectors for gene therapy. Mol Biotechnol 2007; 36: 71–80. ArticleCAS Google Scholar
Hartman ZC, Appledorn DM, Amalfitano A . Adenovirus vector induced innate immune responses: impact upon efficacy and toxicity in gene therapy and vaccine applications. Virus Res 2008; 132: 1–14. ArticleCAS Google Scholar
Sonobe J, Okubo Y, Kaihara S, Miyatake S, Bessho K . Osteoinduction by bone morphogenetic protein 2-expressing adenoviral vector: application of biomaterial to mask the host immune response. Hum Gene Ther 2004; 15: 659–668. ArticleCAS Google Scholar
Wang Y, Yang Z, Liu S, Kon T, Krol A, Li CY et al. Characterisation of systemic dissemination of nonreplicating adenoviral vectors from tumours in local gene delivery. Br J Cancer 2005; 92: 1414–1420. ArticleCAS Google Scholar
Paleos CM, Tziveleka LA, Sideratou Z, Tsiourvas D . Gene delivery using functional dendritic polymers. Expert Opin Drug Deliv 2009; 6: 27–38. ArticleCAS Google Scholar
Ditto AJ, Shah PN, Gump LR, Yun YH . Nanospheres formulated from l-tyrosine polyphosphate exhibiting sustained release of polyplexes and in vitro controlled transfection properties. Mol Pharm 2009; 6: 986–995. ArticleCAS Google Scholar
Traini T, Degidi M, Iezzi G, Artese L, Piattelli A . Comparative evaluation of the peri-implant bone tissue mineral density around unloaded titanium dental implants. J Dent 2007; 35: 84–92. ArticleCAS Google Scholar
Otsu N . Threshold selection method from gray-level histograms. IEEE Trans Syst Man Cybern 1979; 9: 62–66. Article Google Scholar