- Chambers, A. F., Groom, A. C. & MacDonald, I. C. Dissemination and growth of cancer cells in metastatic sites. Nature Rev. Cancer 2, 563–572 (2002)
Article CAS Google Scholar
- Fidler, I. J. The pathogenesis of cancer metastasis: the ‘seed and soil’ hypothesis revisited. Nature Rev. Cancer 3, 453–458 (2003)
Article ADS CAS Google Scholar
- Yokota, J. Tumor progression and metastasis. Carcinogenesis 21, 497–503 (2000)
Article CAS Google Scholar
- Kang, Y. et al. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 3, 537–549 (2003)
Article CAS Google Scholar
- Clark, E. A., Golub, T. R., Lander, E. S. & Hynes, R. O. Genomic analysis of metastasis reveals an essential role for RhoC. Nature 406, 532–535 (2000)
Article ADS CAS Google Scholar
- Yang, J. et al. Twist, a master regulator of morphogenesis, plays an essential role in tumour metastasis. Cell 117, 927–939 (2004)
Article CAS Google Scholar
- Bernards, R. & Weinberg, R. A. A progression puzzle. Nature 418, 823 (2002)
Article ADS CAS Google Scholar
- van de Vijver, M. J. et al. A gene-expression signature as a predictor of survival in breast cancer. N. Engl. J. Med. 347, 1999–2009 (2002)
Article CAS Google Scholar
- van 't Veer, L. J. et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature 415, 530–536 (2002)
Article CAS Google Scholar
- Ramaswamy, S., Ross, K. N., Lander, E. S. & Golub, T. R. A molecular signature of metastasis in primary solid tumors. Nature Genet. 33, 49–54 (2003)
Article CAS Google Scholar
- Solomayer, E. F., Diel, I. J., Meyberg, G. C., Gollan, C. & Bastert, G. Metastatic breast cancer: clinical course, prognosis and therapy related to the first site of metastasis. Breast Cancer Res. Treat. 59, 271–278 (2000)
Article CAS Google Scholar
- Cailleau, R., Olive, M. & Cruciger, Q. V. Long-term human breast carcinoma cell lines of metastatic origin: preliminary characterization. In Vitro 14, 911–915 (1978)
Article CAS Google Scholar
- Minn, A. J. et al. Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors. J. Clin. Invest. 115, 44–55 (2005)
Article CAS Google Scholar
- Shelly, M. et al. Epiregulin is a potent pan-ErbB ligand that preferentially activates heterodimeric receptor complexes. J. Biol. Chem. 273, 10496–10505 (1998)
Article CAS Google Scholar
- Yarden, Y. & Sliwkowski, M. X. Untangling the ErbB signalling network. Nature Rev. Mol. Cell Biol. 2, 127–137 (2001)
Article CAS Google Scholar
- Balkwill, F. Cancer and the chemokine network. Nature Rev. Cancer 4, 540–550 (2004)
Article CAS Google Scholar
- Egeblad, M. & Werb, Z. New functions for the matrix metalloproteinases in cancer progression. Nature Rev. Cancer 2, 161–174 (2002)
Article CAS Google Scholar
- Duffy, M. J., Maguire, T. M., Hill, A., McDermott, E. & O'Higgins, N. Metalloproteinases: role in breast carcinogenesis, invasion and metastasis. Breast Cancer Res. 2, 252–257 (2000)
Article CAS Google Scholar
- Framson, P. E. & Sage, E. H. SPARC and tumour growth: where the seed meets the soil? J. Cell. Biochem. 92, 679–690 (2004)
Article CAS Google Scholar
- Wood, N. et al. Enhanced interleukin (IL)-13 responses in mice lacking IL-13 receptor alpha 2. J. Exp. Med. 197, 703–709 (2003)
Article CAS Google Scholar
- Amatschek, S. et al. Tissue-wide expression profiling using cDNA subtraction and microarrays to identify tumour-specific genes. Cancer Res. 64, 844–856 (2004)
Article CAS Google Scholar
- O'Hanlon, D. M. et al. Soluble adhesion molecules (E-selectin, ICAM-1 and VCAM-1) in breast carcinoma. Eur. J. Cancer 38, 2252–2257 (2002)
Article CAS Google Scholar
- Desprez, P. Y., Sumida, T. & Coppe, J. P. Helix–loop–helix proteins in mammary gland development and breast cancer. J. Mammary Gland Biol. Neoplasia 8, 225–239 (2003)
Article Google Scholar
- Ruzinova, M. B. & Benezra, R. Id proteins in development, cell cycle and cancer. Trends Cell Biol. 13, 410–418 (2003)
Article CAS Google Scholar
- Arun, B. & Goss, P. The role of COX-2 inhibition in breast cancer treatment and prevention. Semin. Oncol. 31, 22–29 (2004)
Article CAS Google Scholar
- Beer, D. G. et al. Gene-expression profiles predict survival of patients with lung adenocarcinoma. Nature Med. 8, 816–824 (2002)
Article CAS Google Scholar
- Perou, C. M. et al. Molecular portraits of human breast tumours. Nature 406, 747–752 (2000)
Article ADS CAS Google Scholar
- Simon, R. Diagnostic and prognostic prediction using gene expression profiles in high-dimensional microarray data. Br. J. Cancer 89, 1599–1604 (2003)
Article CAS Google Scholar
- Hynes, R. O. Metastatic potential: generic predisposition of the primary tumour or rare, metastatic variants-or both? Cell 113, 821–823 (2003)
Article CAS Google Scholar
- Heimann, R. & Hellman, S. Clinical progression of breast cancer malignant behaviour: what to expect and when to expect it. J. Clin. Oncol. 18, 591–599 (2000)
Article CAS Google Scholar
- Schairer, C., Mink, P. J., Carroll, L. & Devesa, S. S. Probabilities of death from breast cancer and other causes among female breast cancer patients. J. Natl. Cancer Inst. 96, 1311–1321 (2004)
Article Google Scholar
- Davidson, B. et al. Altered expression of metastasis-associated and regulatory molecules in effusions from breast cancer patients: a novel model for tumour progression. Clin. Cancer Res. 10, 7335–7346 (2004)
Article ADS CAS Google Scholar
- Ponomarev, V. et al. A novel triple-modality reporter gene for whole-body fluorescent, bioluminescent, and nuclear noninvasive imaging. Eur. J. Nucl. Med. Mol. Imaging 31, 740–751 (2004)
Article CAS Google Scholar