Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide (original) (raw)
Bard, F. & Malhotra, V. The formation of TGN-to-plasma-membrane transport carriers. Annu. Rev. Cell Dev. Biol.22, 439–455 (2006) ArticleCAS Google Scholar
Luini, A., Ragnini-Wilson, A., Polishchuk, R. S. & De Matteis, M. A. Large pleiomorphic traffic intermediates in the secretory pathway. Curr. Opin. Cell Biol.17, 353–361 (2005) ArticleCAS Google Scholar
De Matteis, M. A. & Godi, A. Protein–lipid interactions in membrane trafficking at the Golgi complex. Biochim. Biophys. Acta1666, 264–274 (2004) ArticleCAS Google Scholar
Godi, A. et al. FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P. Nature Cell Biol.6, 393–404 (2004) ArticleCAS Google Scholar
Vieira, O. V., Verkade, P., Manninen, A. & Simons, K. FAPP2 is involved in the transport of apical cargo in polarized MDCK cells. J. Cell Biol.170, 521–526 (2005) ArticleCAS Google Scholar
Vieira, O. V. et al. FAPP2, cilium formation, and compartmentalization of the apical membrane in polarized Madin–Darby canine kidney (MDCK) cells. Proc. Natl Acad. Sci. USA103, 18556–18561 (2006) ArticleADSCAS Google Scholar
Levine, T. P. & Munro, S. Targeting of Golgi-specific pleckstrin homology domains involves both PtdIns 4-kinase-dependent and -independent components. Curr. Biol.12, 695–704 (2002) ArticleCAS Google Scholar
Brown, R. E. & Mattjus, P. Glycolipid transfer proteins. Biochim. Biophys. Acta1771, 746–760 (2007) ArticleCAS Google Scholar
Holthuis, J. C., Pomorski, T., Raggers, R. J., Sprong, H. & Van Meer, G. The organizing potential of sphingolipids in intracellular membrane transport. Physiol. Rev.81, 1689–1723 (2001) ArticleCAS Google Scholar
Nylund, M. et al. Molecular features of phospholipids that affect glycolipid transfer protein-mediated galactosylceramide transfer between vesicles. Biochim. Biophys. Acta1758, 807–812 (2006) ArticleCAS Google Scholar
Wiedemann, C., Schafer, T. & Burger, M. M. Chromaffin granule-associated phosphatidylinositol 4-kinase activity is required for stimulated secretion. EMBO J.15, 2094–2101 (1996) ArticleCAS Google Scholar
Brade, L., Vielhaber, G., Heinz, E. & Brade, H. In vitro characterization of anti-glucosylceramide rabbit antisera. Glycobiology10, 629–636 (2000) ArticleCAS Google Scholar
Malinina, L., Malakhova, M. L., Teplov, A., Brown, R. E. & Patel, D. J. Structural basis for glycosphingolipid transfer specificity. Nature430, 1048–1053 (2004) ArticleADSCAS Google Scholar
Klausner, R. D., Donaldson, J. G. & Lippincott-Schwartz, J. Brefeldin A: insights into the control of membrane traffic and organelle structure. J. Cell Biol.116, 1071–1080 (1992) ArticleCAS Google Scholar
Boot, R. G. et al. Identification of the non-lysosomal glucosylceramidase as β-glucosidase 2. J. Biol. Chem.282, 1305–1312 (2007) ArticleCAS Google Scholar
Yildiz, Y. et al. Mutation of β-glucosidase 2 causes glycolipid storage disease and impaired male fertility. J. Clin. Invest.116, 2985–2994 (2006) ArticleCAS Google Scholar
Hanada, K. et al. Molecular machinery for non-vesicular trafficking of ceramide. Nature426, 803–809 (2003) ArticleADSCAS Google Scholar
Mallard, F. et al. Direct pathway from early/recycling endosomes to the Golgi apparatus revealed through the study of Shiga toxin B-fragment transport. J. Cell Biol.143, 973–990 (1998) ArticleCAS Google Scholar
Young, W. W., Lutz, M. S., Mills, S. E. & Lechler-Osborn, S. Use of brefeldin A to define sites of glycosphingolipid synthesis: GA2/GM2/GD2 synthase is trans to the brefeldin A block. Proc. Natl Acad. Sci. USA87, 6838–6842 (1990) ArticleADSCAS Google Scholar
Mironov, A. A. et al. Dicumarol, an inhibitor of ADP-ribosylation of CtBP3/BARS, fragments golgi non-compact tubular zones and inhibits intra-golgi transport. Eur. J. Cell Biol.83, 263–279 (2004) ArticleCAS Google Scholar
Brown, W. J., Chambers, K. & Doody, A. Phospholipase A2 (PLA2) enzymes in membrane trafficking: mediators of membrane shape and function. Traffic4, 214–221 (2003) ArticleCAS Google Scholar
Drecktrah, D. & Brown, W. J. Phospholipase A2 antagonists inhibit nocodazole-induced Golgi ministack formation: evidence of an ER intermediate and constitutive cycling. Mol. Biol. Cell10, 4021–4032 (1999) ArticleCAS Google Scholar
Trucco, A. et al. Secretory traffic triggers the formation of tubular continuities across Golgi sub-compartments. Nature Cell Biol.6, 1071–1081 (2004) ArticleCAS Google Scholar
Yu, S. et al. mBet3p is required for homotypic COPII vesicle tethering in mammalian cells. J. Cell Biol.174, 359–368 (2006) ArticleCAS Google Scholar
Marra, P. et al. The biogenesis of the Golgi ribbon: the roles of membrane input from the ER and of GM130. Mol. Biol. Cell18, 1595–1608 (2007) ArticleCAS Google Scholar
Toth, B. et al. Phosphatidylinositol 4-kinase IIIβ regulates the transport of ceramide between the endoplasmic reticulum and Golgi. J. Biol. Chem.281, 36369–36377 (2006) ArticleCAS Google Scholar
Rosenwald, A. G., Machamer, C. E. & Pagano, R. E. Effects of a sphingolipid synthesis inhibitor on membrane transport through the secretory pathway. Biochemistry31, 3581–3590 (1992) ArticleCAS Google Scholar
Sprong, H. et al. Glycosphingolipids are required for sorting melanosomal proteins in the Golgi complex. J. Cell Biol.155, 369–380 (2001) ArticleCAS Google Scholar
Schwarz, A. & Futerman, A. H. Distinct roles for ceramide and glucosylceramide at different stages of neuronal growth. J. Neurosci.17, 2929–2938 (1997) ArticleCAS Google Scholar
Boldin, S. A. & Futerman, A. H. Up-regulation of glucosylceramide synthesis upon stimulation of axonal growth by basic fibroblast growth factor. Evidence for post-translational modification of glucosylceramide synthase. J. Biol. Chem.275, 9905–9909 (2000) ArticleCAS Google Scholar
Chang, M. C., Wisco, D., Ewers, H., Norden, C. & Winckler, B. Inhibition of sphingolipid synthesis affects kinetics but not fidelity of L1/NgCAM transport along direct but not transcytotic axonal pathways. Mol. Cell. Neurosci.31, 525–538 (2006) ArticleCAS Google Scholar
Tamboli, I. Y. et al. Inhibition of glycosphingolipid biosynthesis reduces secretion of the β-amyloid precursor protein and amyloid β-peptide. J. Biol. Chem.280, 28110–28117 (2005) ArticleCAS Google Scholar
Lannert, H., Gorgas, K., Meissner, I., Wieland, F. T. & Jeckel, D. Functional organization of the Golgi apparatus in glycosphingolipid biosynthesis. Lactosylceramide and subsequent glycosphingolipids are formed in the lumen of the late Golgi. J. Biol. Chem.273, 2939–2946 (1998) ArticleCAS Google Scholar
Raya, A. et al. Goodpasture antigen-binding protein, the kinase that phosphorylates the Goodpasture antigen, is an alternatively spliced variant implicated in autoimmune pathogenesis. J. Biol. Chem.275, 40392–40399 (2000) ArticleCAS Google Scholar
De Matteis, M. A., Di Campli, A. & D’Angelo, G. Lipid-transfer proteins in membrane trafficking at the Golgi complex. Biochim. Biophys. Acta1771, 761–768 (2007) ArticleCAS Google Scholar
De Matteis, M. A. & Godi, A. PI-loting membrane traffic. Nature Cell Biol.6, 487–492 (2004) ArticleCAS Google Scholar
Malakhova, M. L. et al. Point mutational analysis of the liganding site in human glycolipid transfer protein. Functionality of the complex. J. Biol. Chem.280, 26312–26320 (2005) ArticleCAS Google Scholar
Sala, G., Dupre, T., Seta, N., Codogno, P. & Ghidoni, R. Increased biosynthesis of glycosphingolipids in congenital disorder of glycosylation Ia (CDG-Ia) fibroblasts. Pediatr. Res.52, 645–651 (2002) ArticleCAS Google Scholar
Wing, D. R. et al. High-performance liquid chromatography analysis of ganglioside carbohydrates at the picomole level after ceramide glycanase digestion and fluorescent labeling with 2-aminobenzamide. Anal. Biochem.298, 207–217 (2001) ArticleCAS Google Scholar
Bielawski, J., Szulc, Z. M., Hannun, Y. A. & Bielawska, A. Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography–tandem mass spectrometry. Methods39, 82–91 (2006) ArticleCAS Google Scholar
Godi, A. et al. ADP ribosylation factor regulates spectrin binding to the Golgi complex. Proc. Natl Acad. Sci. USA95, 8607–8612 (1998) ArticleADSCAS Google Scholar
Marra, P. et al. The GM130 and GRASP65 Golgi proteins cycle through and define a subdomain of the intermediate compartment. Nature Cell Biol.3, 1101–1113 (2001) ArticleCAS Google Scholar
Lodish, H. F. & Kong, N. Glucose removal from N-linked oligosaccharides is required for efficient maturation of certain secretory glycoproteins from the rough endoplasmic reticulum to the Golgi complex. J. Cell Biol.98, 1720–1729 (1984) ArticleCAS Google Scholar
Watt, S. A., Kular, G., Fleming, I. N., Downes, C. P. & Lucocq, J. M. Subcellular localization of phosphatidylinositol 4,5-bisphosphate using the pleckstrin homology domain of phospholipase Cδ1. Biochem. J.363, 657–666 (2002) ArticleCAS Google Scholar
Polishchuk, E. V., Di Pentima, A., Luini, A. & Polishchuk, R. S. Mechanism of constitutive export from the golgi: bulk flow via the formation, protrusion, and en bloc cleavage of large trans-golgi network tubular domains. Mol. Biol. Cell14, 4470–4485 (2003) ArticleCAS Google Scholar
Millar, C. A. et al. Adipsin and the glucose transporter GLUT4 traffic to the cell surface via independent pathways in adipocytes. Traffic1, 141–151 (2000) ArticleCAS Google Scholar