Genotype, haplotype and copy-number variation in worldwide human populations (original) (raw)

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Gene Expression Omnibus

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The array data described in this paper are deposited in the Gene Expression Omnibus (http://www.ncbi.nlm.nih.gov/geo) under accession number GSE10331.

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Acknowledgements

We thank the Biological Resource Center at the Fondation Jean Dausset – CEPH for preparing HGDP–CEPH diversity panel DNA samples, and S. Chanock and A. Hutchinson for assistance with the DNAs. This work was supported in part by NIH grants, by a postdoctoral fellowship from the University of Michigan Center for Genetics in Health and Medicine, by grants from the Alfred P. Sloan Foundation and the Burroughs Wellcome Fund, by the National Center for Minority Health and Health Disparities, and by the Intramural Program of the National Institute on Aging. The study used the Biowulf Linux cluster at the National Institutes of Health (http://biowulf.nih.gov).

Author Contributions N.A.R. and A.B.S. wish to be regarded as joint last authors.

Author information

Author notes

1. Mattias Jakobsson, Sonja W. Scholz and Paul Scheet: These authors contributed equally to this work.

Authors and Affiliations

1. Center for Computational Medicine and Biology,,
   Mattias Jakobsson, Paul Scheet, Jenna M. VanLiere, Zachary A. Szpiech, James H. Degnan & Noah A. Rosenberg
2. Department of Human Genetics,,
   Mattias Jakobsson, James H. Degnan & Noah A. Rosenberg
3. Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA,
   Paul Scheet & Noah A. Rosenberg
4. Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA,
   Sonja W. Scholz, J. Raphael Gibbs, Hon-Chung Fung, Rita Guerreiro, Jose M. Bras, Jennifer C. Schymick, Dena G. Hernandez, Bryan J. Traynor, Javier Simon-Sanchez, Mar Matarin, Angela Britton, Joyce van de Leemput, Ian Rafferty & Andrew B. Singleton
5. Department of Molecular Neuroscience and Reta Lila Weston Institute of Neurological Studies, Institute of Neurology, University College London, Queen Square, London WC1N 3BG, UK,
   Sonja W. Scholz, J. Raphael Gibbs, Joyce van de Leemput & John A. Hardy
6. Department of Neurology, Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Taipei 10591, Taiwan
   Hon-Chung Fung
7. Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA,
   Kai Wang & Maja Bucan
8. Center for Neurosciences and Cell Biology, Faculty of Medicine, University of Coimbra, 3004-504 Coimbra, Portugal
   Rita Guerreiro & Jose M. Bras
9. Department of Clinical Neurology, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK
   Jennifer C. Schymick
10. Neurogenetics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA,
    Bryan J. Traynor
11. Departamento de Genómica y Proteómica, Unidad de Genética Molecular, Instituto de Biomedicina de Valencia-CSIC, 46010, Valencia, Spain,
    Javier Simon-Sanchez
12. Fondation Jean Dausset – Centre d’Étude du Polymorphisme Humain (CEPH), 27 rue Juliette Dodu, 75010 Paris, France,
    Howard M. Cann
13. Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia 22908, USA,
    Andrew B. Singleton

Authors

1. Mattias Jakobsson
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2. Sonja W. Scholz
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3. Paul Scheet
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4. J. Raphael Gibbs
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5. Jenna M. VanLiere
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6. Hon-Chung Fung
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7. Zachary A. Szpiech
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8. James H. Degnan
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9. Kai Wang
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10. Rita Guerreiro
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11. Jose M. Bras
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12. Jennifer C. Schymick
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13. Dena G. Hernandez
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14. Bryan J. Traynor
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15. Javier Simon-Sanchez
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16. Mar Matarin
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17. Angela Britton
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18. Joyce van de Leemput
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19. Ian Rafferty
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20. Maja Bucan
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21. Howard M. Cann
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22. John A. Hardy
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23. Noah A. Rosenberg
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24. Andrew B. Singleton
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Corresponding authors

Correspondence toNoah A. Rosenberg or Andrew B. Singleton.

Supplementary information

Supplementary Information

This file contains extensive Supplementary Information with Supplementary Notes, Supplementary Data, Supplementary Tables S1-S17, Supplementary Figures S1-S30 with Legends and additional references. (PDF 10195 kb)

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Jakobsson, M., Scholz, S., Scheet, P. et al. Genotype, haplotype and copy-number variation in worldwide human populations.Nature 451, 998–1003 (2008). https://doi.org/10.1038/nature06742

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• Received: 02 December 2007
• Accepted: 29 January 2008
• Issue Date: 21 February 2008
• DOI: https://doi.org/10.1038/nature06742