The zinc-finger protein Zelda is a key activator of the early zygotic genome in Drosophila (original) (raw)

References

1. Newport, J. & Kirschner, M. A major developmental transition in early Xenopus embryos: II. Control of the onset of transcription. Cell 30, 687–696 (1982)
   Article CAS PubMed Google Scholar
2. Giraldez, A. J. et al. Zebrafish miR-430 promotes deadenylation and clearance of maternal mRNAs. Science 312, 75–79 (2006)
   Article ADS CAS PubMed Google Scholar
3. Bushati, N., Stark, A., Brennecke, J. & Cohen, S. Temporal reciprocity of miRNAs and their targets during the maternal-to-zygotic transition in Drosophila . Curr. Biol. 18, 501–506 (2008)
   Article CAS PubMed Google Scholar
4. Tadros, W. et al. SMAUG is a major regulator of maternal mRNA destabilization in Drosophila and its translation is activated by the PAN GU kinase. Dev. Cell 12, 143–155 (2007)
   Article CAS PubMed Google Scholar
5. ten Bosch, J. R., Benavides, J. A. & Cline, T. W. The TAGteam DNA motif controls the timing of Drosophila pre-blastoderm transcription. Development 133, 1967–1977 (2006)
   Article CAS PubMed Google Scholar
6. De Renzis, S. D., Elemento, O., Tavazoie, S. & Wieschaus, E. F. Unmasking activation of the zygotic genome using chromosomal deletions in the Drosophila embryo. PLoS Biol. 5, 1036–1051 (2007)
   Article CAS Google Scholar
7. Li, X. et al. Transcription factors bind thousands of active and inactive regions in the Drosophila blastoderm. PLoS Biol. 6, 365–388 (2008)
   CAS Google Scholar
8. Jiang, J., Rushlow, C. A., Zhou, Q., Small, S. & Levine, M. Individual Dorsal morphogen binding sites mediate activation and repression in the Drosophila embryo. EMBO J. 11, 3147–3154 (1992)
   Article CAS PubMed PubMed Central Google Scholar
9. Kirov, N., Zhelnin, L., Shah, J. & Rushlow, C. Conversion of a silencer into an enhancer: evidence for a co-repressor in dorsal-mediated repression in Drosophila . EMBO J. 12, 3193–3199 (1993)
   Article CAS PubMed PubMed Central Google Scholar
10. Staudt, N., Fellert, S., Chung, H., Jäckle, H. & Vorbrüggen, G. Mutations of the Drosophila zinc finger-encoding gene vielfältig impair mitotic cell divisions and cause improper chromosome segregation. Mol. Biol. Cell 17, 2356–2365 (2006)
    Article CAS PubMed PubMed Central Google Scholar
11. Bourbon, H. M. et al. A P-insertion screen identifying novel X-linked essential genes in Drosophila . Mech. Dev. 110, 71–83 (2002)
    Article CAS PubMed Google Scholar
12. Simpson, L. & Wieschaus, E. F. Zygotic activity of the nullo locus is required to stabilize the actin-myosin network during cellularizatiron in Drosophila . Development 110, 851–863 (1990)
    CAS PubMed Google Scholar
13. Schweisguth, F., Lepesant, J. A. & Vincent, A. The serendipity alpha gene encodes a membrane-associated protein required for the cellularization of the Drosophila embryo. Genes Dev. 4, 922–931 (1990)
    Article CAS PubMed Google Scholar
14. Lecuit, T., Samanta, R. & Wieschaus, E. slam encodes a developmental regulator of polarized membrane growth during cleavage of the Drosophila embryo. Dev. Cell 2, 425–436 (2002)
    Article CAS PubMed Google Scholar
15. Stein, J. A., Broihier, H. T., Moor, L. A. & Lehmann, R. Slow as molasses is required for polarized membrane growth and germ cell migration in Drosophila . Development 129, 3925–3934 (2002)
    CAS PubMed Google Scholar
16. Grosshans, J., Müller, H. & Wieschaus, E. Control of cleavage cycles in Drosophila embryos by frühstart . Dev. Cell 5, 285–294 (2003)
    Article CAS PubMed Google Scholar
17. Robinson, D. N. & Cooley, L. Examination of the function of two kelch proteins generated by stop codon suppression. Development 124, 1405–1417 (1997)
    CAS PubMed Google Scholar
18. Stathopoulos, A. & Levine, M. Genomic regulatory networks and animal development. Dev. Cell 9, 449–462 (2005)
    Article CAS PubMed Google Scholar
19. Markstein, M., Markstein, P., Markstein, V. & Levine, M. S. Genome-wide analysis of clustered Dorsal binding sites identifies putative target genes in the Drosophila embryo. Proc. Natl Acad. Sci. USA 99, 763–768 (2002)
    Article ADS CAS PubMed Google Scholar
20. Gross, S. P., Guo, Y., Martinez, J. E. & Welte, M. A. A determinant for directionality of organelle transport in Drosophila embryos. Curr. Biol. 13, 1660–1668 (2003)
    Article CAS PubMed Google Scholar
21. Pilot, F., Philippe, J. M., Lemmers, C., Chauvin, J. P. & Lecuit, T. Developmental control of nuclear morphogenesis and anchoring by charleston, identified in a functional genomic screen of Drosophila cellularization. Development 133, 711–723 (2006)
    Article CAS PubMed Google Scholar
22. Biemar, F. et al. Spatial regulation of microRNA gene expression in the Drosophila embryo. Proc. Natl Acad. Sci. USA 102, 15907–15911 (2005)
    Article ADS CAS PubMed PubMed Central Google Scholar
23. Gunsalus, K. C. et al. Predictive models of molecular machines involved in Caenorhabditis elegans early embryogenesis. Nature 436, 861–865 (2005)
    Article ADS CAS PubMed Google Scholar
24. Ryder, E. et al. The DrosDel collection: a set of P-element insertions for generating custom chromosomal aberrations in Drosophila melanogaster . Genetics 167, 797–813 (2004)
    Article CAS PubMed PubMed Central Google Scholar
25. Chou, T. B., Noll, E. & Perrimon, N. Autosomal P[ovo _D1_] dominant female-sterile insertions in Drosophila and their use in generating germ-line chimeras. Development 119, 1359–1369 (1993)
    CAS PubMed Google Scholar
26. Chou, T. B. & Perrimon, N. The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster . Genetics 144, 1673–1679 (1996)
    CAS PubMed PubMed Central Google Scholar
27. Yu, Y. et al. The nuclear hormone receptor Ftz-F1 is a cofactor for the Drosophila homeodomain protein. Nature 385, 552–555 (1997)
    Article ADS CAS PubMed Google Scholar
28. Kirkpatrick, H., Johnson, K. & Laughon, A. Repression of dpp targets by binding of brinker to mad sites. J. Biol. Chem. 276, 18216–18222 (2001)
    Article CAS PubMed Google Scholar

Download references