Fine-tuned amplification in cells (original) (raw)

Gene regulation

Nature volume 511, pages 417–418 (2014)Cite this article

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The transcription factor Myc has been posited to cause a cell-wide increase in gene expression. But two studies show that Myc, when modulated by other transcription factors, can amplify select targets. See Letters p.483 and p.488

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Figure 1: Models of Myc function.

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Authors and Affiliations

  1. Chi V. Dang is at the Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.,
    Chi V. Dang

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Correspondence toChi V. Dang.

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Dang, C. Fine-tuned amplification in cells.Nature 511, 417–418 (2014). https://doi.org/10.1038/nature13518

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