Fine-tuned amplification in cells (original) (raw)
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- Published: 09 July 2014
Gene regulation
Nature volume 511, pages 417–418 (2014)Cite this article
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The transcription factor Myc has been posited to cause a cell-wide increase in gene expression. But two studies show that Myc, when modulated by other transcription factors, can amplify select targets. See Letters p.483 and p.488
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Figure 1: Models of Myc function.

References
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Authors and Affiliations
- Chi V. Dang is at the Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.,
Chi V. Dang
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Correspondence toChi V. Dang.
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Dang, C. Fine-tuned amplification in cells.Nature 511, 417–418 (2014). https://doi.org/10.1038/nature13518
- Published: 09 July 2014
- Issue date: 24 July 2014
- DOI: https://doi.org/10.1038/nature13518